Fig. 1.
Ion chromatograms of A – a blank sow’s milk sample; B – a milk sample fortified with tylosin (TYL) at 50 μg/L; C – a milk sample at the concentration of 883 μg/L obtained one day after tylosin injection. cps – counts per s; IS – internal standard
Table 1.
Validation parameters of the method for the analysis of tylosin in sow’s milk
| Analyte | Fortification level (μg/L) | Repeatability (%) | Reproducibility (%) | Recovery (%) |
|---|---|---|---|---|
| Tylosin | 5.0 | 9.2 | 13.8 | 98.2 |
| 50.0 | 7.0 | 6.7 | 105.8 | |
| 100.0 | 4.7 | 4.1 | 100.6 |
Fig. 2.
The tylosin concentration–time profile in sow’s milk (n = 5) following treatment consisting of three injectable daily doses of 10 mg of the antibiotic per kg of body weight. SE – standard error; SD – standard deviation
Table 2.
Tylosin residues in milk samples (μg/L) after the intramuscular administration of the antibiotic