Phytotherapeutic potential of Artemisia ludoviciana and Cordia boissieri extracts against the dermatophyte Microsporum canis Cover

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Phytotherapeutic potential of Artemisia ludoviciana and Cordia boissieri extracts against the dermatophyte Microsporum canis

Journal of Veterinary Research

Volume 68 (2024): Issue 3 (September 2024)

By: José Pablo Villarreal Villarreal , Beatriz A. Medina Soto , Michel Stéphane Heya , Sergio A. Galindo-Rodríguez , Uziel Castillo Velázquez , Kevin A. Cárdenas Noriega and Romario García-Ponce

Open Access

|Aug 2024

Figures & Tables

Cell viability of HaCaT human keratinocyte cells exposed to different concentration of extracts of Artemisia ludoviciana and Cordia boissieri. Determination of viability was by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay (A) and trypan blue dye (B) Control – DMSO; P-value ≤ 0.05

Phytochemical characterisation of methanolic extracts of Artemisia ludoviciana and Cordia boissieri

Phytochemical group	A. ludoviciana	C. boissieri
Sterols and triterpenes	+	+
Sesquiterpene lactones	+	+
Coumarins	+	−
Saponins	+	+
Flavonoids	+	+
Alkaloids	−	−
Aromatics	+	+
Carbonyls	−	−
Phenolic oxides	+	+

Inhibition activity of methanolic extracts of Artemisia ludoviciana and Cordia boissieri against Microsporum canis

Extract	Concentration	% H
	1,250 μg/mL	85.92 ± 7.34^a
A. ludoviciana	2,500 μg/mL	94.30 ± 5.84^a
	5,000 μg/mL	99.63 ± 1.24^a
	625 μg/mL	77.11 ± 4.32^b
C. boissieri	1,250 μg/mL	94.12 ± 3.56^a
	2,500 μg/mL	100.00 ± 0.00^a
Imidazole	1,000 μg/mL	90.25 ± 3.44^a

Minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) of methanolic extracts of Artemisia ludoviciana and Cordia boissieri against Microsporum canis

Extract	MIC	MFC
A. ludoviciana	2,500 μg/mL	5,000 μg/mL
C. boissieri	1,250 μg/mL	2,500 μg/mL

DOI: https://doi.org/10.2478/jvetres-2024-0046 | Journal eISSN: 2450-8608

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Language: English

Page range: 389 - 394

Submitted on: Jan 12, 2024

Accepted on: Aug 1, 2024

Published on: Aug 7, 2024

Published by: National Veterinary Research Institute in Pulawy

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

antifungal resistance,

dermatophytosis,

Related subjects:

Molecular biology,

Microbiology and virology,

Life sciences, other,

Veterinary medicine

© 2024 José Pablo Villarreal Villarreal, Beatriz A. Medina Soto, Michel Stéphane Heya, Sergio A. Galindo-Rodríguez, Uziel Castillo Velázquez, Kevin A. Cárdenas Noriega, Romario García-Ponce, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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