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Clinicopathological analysis of expression of enhancer of zeste homologue 2 in canine mammary carcinoma Cover

Clinicopathological analysis of expression of enhancer of zeste homologue 2 in canine mammary carcinoma

Journal of Veterinary Research
Volume 66 (2022): Issue 2 (June 2022)
By: Xiaoli Ren,  Yuying Fan,  Yongqi Li,  Dongmei Shi and  Yun Liu  
Open Access
|Jul 2022

Figures & Tables

Fig. 1

Transcription level of the EZH2 gene in canine normal mammary gland and CMC tissuesA – normal canine mammary tissues; B – infiltrating ductal carcinoma; C – intraductal papillary carcinomas; D – infiltrating micropapillary carcinoma; E – ductal carcinoma in situ Results are presented as mean ± SD of tissues in the group. * P < 0.05 and ** P < 0.01 show significantly different by one ANOVA test
Transcription level of the EZH2 gene in canine normal mammary gland and CMC tissuesA – normal canine mammary tissues; B – infiltrating ductal carcinoma; C – intraductal papillary carcinomas; D – infiltrating micropapillary carcinoma; E – ductal carcinoma in situ Results are presented as mean ± SD of tissues in the group. * P < 0.05 and ** P < 0.01 show significantly different by one ANOVA test

Fig. 2

Expression of the EZH2 protein in normal canine mammary gland and CMC tissue as revealed by immunohistochemical staining (200 ×)A – normal canine mammary tissues; B – infiltrating ductal carcinoma; C – intraductal papillary carcinomas; D – infiltrating micropapillary carcinoma; E – ductal carcinoma in situ. Scale bars: 50 μm
Expression of the EZH2 protein in normal canine mammary gland and CMC tissue as revealed by immunohistochemical staining (200 ×)A – normal canine mammary tissues; B – infiltrating ductal carcinoma; C – intraductal papillary carcinomas; D – infiltrating micropapillary carcinoma; E – ductal carcinoma in situ. Scale bars: 50 μm

Relationship between expression of EZH2 and clinicopathological factors in CMCs

CharacteristicsNExpression of EZH2 protein（n）P
-+
Age 0.836
＜1018812
≥10351520
Size (cm) 0.186
＜31697
3–5cm28820
≥5945
Histological grade 0.011
I16115
II30723
III734
Metastatic state 0.424
Yes1248
No411922
Histological type 0.489
Infiltrating ductal carcinoma411225
Intraductal papillary carcinoma642
Invasive micropapillary carcinoma321
Ductal carcinoma in situ312
DOI: https://doi.org/10.2478/jvetres-2022-0033 | Journal eISSN: 2450-8608
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Language: English
Page range: 267 - 272
Submitted on: Dec 22, 2021
Accepted on: Jun 20, 2022
Published on: Jul 5, 2022
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
canine mammary carcinoma,
EZH2,
clinicopathological examination
Related subjects:
Life sciences,
Molecular biology,
Microbiology and virology,
Life sciences, other,
Medicine,
Veterinary medicine

© 2022 Xiaoli Ren, Yuying Fan, Yongqi Li, Dongmei Shi, Yun Liu, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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