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In vivo study of the oestrogenic activity of milk Cover

In vivo study of the oestrogenic activity of milk

By: Lidia Radko and  Andrzej Posyniak  
Open Access
|Sep 2021

Figures & Tables

Uterotrophic effects of different kinds of milk in immature female hamsters

GroupBody weightWet weight of the uterusDry weight of the uterus

InitialTerminalPercentage gainAbsolute (mg)Fold induction over controlRelative (mg/100g)Absolute (mg)Relative (mg/100g)
Negative control13.7 ± 2.1425.2 ± 3.5483.935.0 ± 6.531139 ± 12.77.1 ± 1.2028.1 ± 2.60
Raw milk from individual cows
14.6 ± 1.2327.7 ± 1.47 33.1 ± 3.03 122 ± 13.56.2 ± 0.7122.3 ± 3.10
1P < 0.055P < 0.11889.7P < 0.2150.96P < 0.060P < 0.053P < 0.060
13.7 ± 2.6122.2 ± 3.37 26.1 ± 7.98 117 ± 14.74.9 ± 1.59*22.0 ± 3.45
2P < 0.832P < 0.18662.0P < 0.0660.75P < 0.055P < 0.045P < 0.080
13.7 ± 1.7223.7 ± 2.33 27.9 ± 5.62 118 ± 26.85.7 ± 1.0024.4 ± 5.36
3P < 0.908P < 0.61373.0P < 0.0600.80P < 0.065P < 0.070P < 0.064
414.7 ± 1.8425.4 ± 3.2072.828.4 ± 5.860.81112 ± 18.15.6 ± 0.8222.0 ± 3.17
P < 0.318P < 0.999 P < 0.055 P < 0.074P < 0.059P < 0.051
514.6 ± 1.5224.2 ± 2.2265.828.9 ± 4.280.83120 ± 16.06.0 ± 1.2025.0 ± 4.41
P < 0.243P < 0.633 P < 0.061 P < 0.061P < 0.054P < 0.062
Retail milk
613.7 ± 2.6327.6 ± 3.2110136.6 ± 6.331.05119 ± 16.56.7 ± 0.9721.8 ± 3.00*
P < 0.610P < 0.077 P < 0.305 P < 0.070P < 0.237P < 0.031
712.7 ± 1.3322.4 ± 2.3076.426.0 ± 4.350.74116 ± 17.95.0 ± 0.82*22.4 ± 3.66
P < 0.075P < 0.187 P < 0.052 P < 0.060P < 0.046P < 0.062
812.0 ± 0.8022.4 ± 1.7686.736.6 ± 8.911.05162 ± 25.37.6 ± 2.0533.6 ± 6.03
P < 0.352P < 0.107 P < 0.346 P < 0.062P < 0.266P < 0.059
912.3 ± 0.6824.9 ± 2.2410243.7 ± 6.241.25175 ± 17.68.0 ± 0.3331.9 ± 3.11
P < 0.056P < 0.949 P < 0.063 P < 0.071P < 0.088P < 0.053
12.6 ± 2.8126.0 ± 3.83 127 ± 24.6*** 493 ± 64.9***19.6 ± 4.13***76.3 ± 11.70***
Positive controlP < 0.355P < 0.855106P < 0.00083.63P < 0.0006P < 0.0007P < 0.0008

Mann–Whitneytest P < 0.058 P < 0.082P < 0.084P < 0.061

Milk sample origins and type

Sample numberRaw milk from individual animals
1Cow, 120 days of lactation
2Cow, 126 days of lactation
3Cow, 110 days of lactation
4Cow, 122 days of lactation
5Cow, 135 days of lactation

Retail milk

6whole-fat cow’s milk, UHT
7whole-fat cow’s milk, pasteurized
8reduced-fat cow’s milk, UHT
9fat-free cow’s milk, UHT
Language: English
Page range: 335 - 340
Submitted on: Mar 30, 2021
Accepted on: Aug 26, 2021
Published on: Sep 23, 2021
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2021 Lidia Radko, Andrzej Posyniak, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.