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Selected tumour biomarker levels in sheep with pulmonary adenomatosis Cover

Selected tumour biomarker levels in sheep with pulmonary adenomatosis

Open Access
|Mar 2020

Figures & Tables

Fig. 1

Macroscopic appearance of the lungs. A – grey-white tumoural foci on a diaphragmatic lung lobe; B – large foci consisting of merged small foci; C – effusive greyish tumoural foci in cross-section of the lung
Macroscopic appearance of the lungs. A – grey-white tumoural foci on a diaphragmatic lung lobe; B – large foci consisting of merged small foci; C – effusive greyish tumoural foci in cross-section of the lung

Fig. 2

Microscopic appearance of the lungs. A – type-II pneumocytes proliferating in alveolar lumen and numerous macrophages on adjacent alveoli; H&E, Bar: 200 μm; B – type-II pneumocytes proliferating in alveolar lumen and numerous macrophages on adjacent alveoli; H&E, Bar: 100 μm; C – type-II pneumocyte cells proliferating in alveolar lumens; H&E, Bar: 20 μm
Microscopic appearance of the lungs. A – type-II pneumocytes proliferating in alveolar lumen and numerous macrophages on adjacent alveoli; H&E, Bar: 200 μm; B – type-II pneumocytes proliferating in alveolar lumen and numerous macrophages on adjacent alveoli; H&E, Bar: 100 μm; C – type-II pneumocyte cells proliferating in alveolar lumens; H&E, Bar: 20 μm

Tumour biomarker results in healthy and OPA sheep

Tumor biomarkerControl (x̅ ±Sx̅)OPA (x̅ ±Sx̅)
CEA (ng/mL)<0.5<0.5
CA 19-9 (U/mL)1.495 ± 0.1041.759 ± 0.151

Means in the same row with asterisks are statistically significant (P < 0.05)

CA 15-3 (U/mL)1.028 ± 0.1461.481 ± 0.156

Means in the same row with asterisks are statistically significant (P < 0.05)

CA 125 (U/mL)<11.235 ± 0.211

Means in the same row with asterisks are statistically significant (P < 0.05)

AFP-3 (ng/mL)0.0010.038 ± 0.017

Means in the same row with asterisks are statistically significant (P < 0.05)

Language: English
Page range: 39 - 44
Submitted on: Jul 7, 2019
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Accepted on: Feb 21, 2020
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Published on: Mar 8, 2020
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 Cumali Özkan, Serkan Yıldırım, Zübeyir Huyut, Mustafa Özbek, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.