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Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs Cover

Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs

Open Access
|Feb 2020

Figures & Tables

Concentration of urinary markers in sick Dobermann dogs divided into subgroups (expressed as mean and range)

VariableSubgroup A (n – 5)Subgroup B (n – 5)
uRBP/uCr (mg/g)15.8 (2.6–ALD)*0.38 (0.27–0.43)
uTHP/uCr (mg/g)0.093 (0–0.093)1.52 (0.39–3.7)*
uIgG/uCr (mg/g)742.77 (34.02–2410.81)*50.5 (0–85.17)

Results for blood biochemical parameters in sick Dobermann dogs and healthy dogs (expressed as mean and range)

Variable (reference range)Dobermann dogs (n = 10) Mean (range)Healthy dogs (n = 12) Mean (range)
Alanine transferase (u/L) (3–50)43 (35–49)47 (21–101)
Aspartate aminotransferase (u/L) (1–37)18 (24–38)28 (18–46)
Total bilirubin (mg/dL) (≤ 0.60)0.36 (0.27–0.47)0.2 (0.1–0.5)
Urea (mg/dL) (20.0–45.0)35.9 (24.6–36.6)37.7 (27.5–59.7)
Creatinine (μmol/L) (88–150)114.9 (79.6–141.4)106.1 (53–150.3)
Alkaline phosphatase (u/L) (20–155)137 (98–150)122 (110–143)
Glucose (mg/dL) (70–120)98 (80–118)117.2 (66–136)
Albumin (g/dL) (3.30–5.60)3.54 (3.34–3.80)3.7 (3.3–4.5)
Total protein (g/dL) (5.50–7.00)6.26 (5.23–6.90)6.7 (2.2–8.6)
Amylase (u/L) (388–1800)595 (422–743)602 (498–703)
Gamma glutamylotransferase (u/L) (5–25)18 (12–24)14 (8–23)

Results for routine urinary parameters of renal function in sick Dobermann dogs and healthy dogs (expressed as mean and range)

VariableDobermann dogs (n = 10)Healthy dogs (n = 12)
uCr (mg/dL)74.1 (20.0–149.6)135.64 (53.91–212.82)
Specific gravity1.03 (1.02–1.03)1.03
UPC1.3 (0.5–2.3)<0.5

Concentrations of urinary markers in sick Dobermann dogs and healthy dogs (expressed as mean and range)

VariableDoberman Pinscher dogs (n = 10)Healthy dogs (n = 12)
uRBP/uCr (mg/g)2.82 (0.27–10.3)*0.23 (0.08–0.41)
uTHP/uCr (mg/g)0.7 (0–3.7)0.2 (0–0.45)
uIgG/uCr (mg/g)460.4 (34.02–2410.81)*0
Language: English
Page range: 181 - 186
Submitted on: May 8, 2019
Accepted on: Feb 4, 2020
Published on: Feb 14, 2020
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 Dagmara Winiarczyk, Łukasz Adaszek, Jacek Madany, Mateusz Winiarczyk, Stanisław Winiarczyk, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.