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Prevalence of BTb by municipality as confirmed by positive isolation of M_ bovis in culture
| Municipality | Positive cases | Negative cases | Total animals sampled | Regional prevalence | Total prevalence |
|---|---|---|---|---|---|
| Tepatitlán de Morelos | 33 | 197 | 230 | 14.3 | 9.9 |
| San Miguel el Alto | 9 | 38 | 47 | 19.1 | 2.7 |
| Arandas | 8 | 47 | 55 | 14.5 | 2.4 |
| TOTAL | 50 | 282 | 332 |
Spoligotype patterns obtained for isolates of M_ bovis from the region of Altos Sur in Jalisco, Mexico_ The total number of isolates per spoligotype is in parentheses
Type of tissue sampled which showed typical BTb lesions
| Type of tissue | Number of samples with lesions | % |
|---|---|---|
| Lymph nodes | ||
| Maxillary | 2 | 2.9 |
| Retropharyngeal | 18 | 26.4 |
| Mediastinal | 22 | 32.4 |
| Lung | 3 | 4.4 |
| Liver | 1 | 1.5 |
| Multiple tissue lesions | ||
| retropharyngeal and maxillary | 1 | 1.5 |
| retropharyngeal and mediastinal | 9 | 13.2 |
| retropharyngeal and lung | 3 | 4.4 |
| retropharyngeal, mediastinal and lung | 4 | 5.9 |
| maxillary and mediastinal | 1 | 1.5 |
| mediastinal and lung | 4 | 5.9 |
| TOTAL | 68 | 100 |
Genetic diversity within the three major clades obtained by WGS of M_ bovis isolates from the region of Altos Sur in Jalisco, Mexico
| Clade | Isolates | Spoligotypes | Municipalities |
|---|---|---|---|
| I | 16 | SB0673, SB0971, NF | Tepatitlán de Morelos, Arandas, San Miguel el Alto |
| II | 8 | SB0130, SB0145, SB1758, SB1216, SB0872 | Tepatitlán de Morelos, Arandas, San Miguel el Alto |
| III | 10 | SB0121, SB1177 | Tepatitlán de Morelos, Arandas, San Miguel el Alto |
Contribution of the total number of samples by municipality
| Municipality | Number of samples | Percentage of the total sample size |
|---|---|---|
| Tepatitlán de Morelos | 230 | 69 |
| Arandas | 55 | 17 |
| San Miguel el Alto | 47 | 14 |
| TOTAL | 332 | 100 |