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Influence of inosine pranobex on cell viability in normal fibroblasts and liver cancer cells

Journal of Veterinary Research
Volume 62 (2018): Issue 2 (June 2018)
By:
Open Access
|Jul 2018

Figures & Tables

Fig. 1

Cytotoxicity of inosine pranobex in BALB/ 3T3 clone A31 and HepG2 lines detected with the MTT assay, n = 6. Values are given as percentage of cell viability relative to control cells. *P < 0.05, compared with control cells
Cytotoxicity of inosine pranobex in BALB/ 3T3 clone A31 and HepG2 lines detected with the MTT assay, n = 6. Values are given as percentage of cell viability relative to control cells. *P < 0.05, compared with control cells

Fig. 2

Cytotoxicity of inosine pranobex in BALB/3T3 clone A31 and HepG2 lines detected with the LDH assay, n = 6. Values are given as percentage of LDH released. *P < 0.05, compared with control cells
Cytotoxicity of inosine pranobex in BALB/3T3 clone A31 and HepG2 lines detected with the LDH assay, n = 6. Values are given as percentage of LDH released. *P < 0.05, compared with control cells

Fig. 3

Cytotoxicity of inosine pranobex in BALB/3T3 clone A31 and HepG2 lines detected with the NRU assay, n = 6. Values are given as percentage of cell viability relative to control cells. *P < 0.05, compared with control cells
Cytotoxicity of inosine pranobex in BALB/3T3 clone A31 and HepG2 lines detected with the NRU assay, n = 6. Values are given as percentage of cell viability relative to control cells. *P < 0.05, compared with control cells

Cytotoxicity of inosine pranobex_ Inhibitory concentration (IC50, μg/mL)

BALB/ 3T3 clone A31 lineHepG2 line
MTT reduction assay50050
LDH release assay10010
NRU assay500100
DOI: https://doi.org/10.2478/jvetres-2018-0031 | Journal eISSN: 2450-8608
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Language: English
Page range: 215 - 220
Submitted on: Mar 29, 2018
Accepted on: Jun 21, 2018
Published on: Jul 7, 2018
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
inosine pranobex,
cell culture,
cytotoxicity
Related subjects:
Life sciences,
Molecular biology,
Microbiology and virology,
Life sciences, other,
Medicine,
Veterinary medicine

© 2018 Sylwia Tobólska, Sylwia Terpiłowska, Jerzy Jaroszewski, Andrzej Krzysztof Siwicki, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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