Pyrrolizidine alkaloids in honey: determination with liquid chromatography-mass spectrometry method
References
- Beales K.A., Betteridge K., Colegate S.M., Edgar J.A.: Solid-phase extraction and LC-MS analysis of pyrrolizidine alkaloids in honeys. J Agric Food Chem 2004, 52, 6664–6672.
- Betteridge K., Cao Y., Colegate S.M.: Improved method for extraction and LC-MS analysis of pyrrolizidine alkaloids and their N-oxides in honey: application to Echium vulgare honeys. J Agric Food Chem 2005, 53, 1894–1902.
- Bodi D., Ronczka S., Gottschalk C., Behr N., Skibba A., Wagner M., Lahrssen-Wiederholt M., Preiss-Weigert A., These A.: Determination of pyrrolizidine alkaloids in tea, herbal drugs, and honey. Food Addit Contam Part A 2014, 31, 1886–1895.
- Boppré M.: The ecological context of pyrrolizidine alkaloids in food, feed, and forage: an overview. Food Addit Contam Part A 2011, 28, 260–281.
- Boppré M., Colegate S.M., Edgar J.A.: Pyrrolizidine alkaloids of Echium vulgare honey found in pure pollen. J Agric Food Chem 2005, 53, 594–600.
- Chung S.W.C., Lam A.C.H.: Investigation of pyrrolizidine alkaloids including their respective N-oxides in selected food products available in Hong Kong by liquid chromatography electrospray ionisation mass spectrometry. Food Add Contam Part A 2017, 34, 1184–1192.
- Cramer L., Beuerle T.: Detection and quantification of pyrrolizidine alkaloids in antibacterial medical honeys. Planta Med 2012, 78, 1976–1982.
- Dübecke A., Beckh G., Lüllmann C.: Pyrrolizidine alkaloids in honey and bee pollen. Food Addit Contam Part A 2011, 28, 348–358.
- Edgar J.A., Colegate S.M., Boppre M., Molyneux R.J.: Pyrrolizidine alkaloids in food: a spectrum of potential health consequences. Food Addit Contam Part A 2011, 28, 308–324.
- Edgar J.A., Molyneux R.J., Colegate S.M.: Pyrrolizidine alkaloids: potential role in the etiology of cancers, pulmonary hypertension, congenital anomalies, and liver disease. Chem Res Toxicol 2015, 28, 4–20.
- Edgar J.A., Roeder E., Molyneaux R.J.: Honey from plants containing pyrrolizidine alkaloids: a potential threat to health. J Agric Food Chem 2002, 50, 2719–2730.
- El Hawari K., Mokh S., Doumyati S., Al Iskandarani M., Verdon E.: Development and validation of a multiclass method for the determination of antibiotic residues in honey using liquid chromatography-tandem mass spectrometry. Food Add Contam Part A 2017, 34, 582–597.
- European Food Safety Authority, EFSA Panel on Contaminants in the Food Chain (CONTAM). Scientific opinion on pyrrolizidine alkaloids in food and feed. EFSA J 2011, 9, 2406, 1–134.
- European Food Safety Authority (EFSA). Dietary exposure assessment to pyrrolizidine alkaloids in the European population. EFSA J 2016, 14, 4572, 1–50.
- European Food Safety Authority, EFSA Panel on Contaminants in the Food Chain (CONTAM). Risks for human health related to the presence of pyrrolizidine alkaloids in honey, tea, herbal infusions and food supplements. EFSA J 2017, 15, 4908, 1–34.
- European Food Safety Authority. Summary report of the standing committee on the food chain and animal health, held in Brussels on 11 July 2012, section toxicological safety of the food chain. 2012, http://www.efsa.europa.eu/en/efsajournal/doc/2406.pdf.
- Griffin C.T., Danaher M., Elliott C.T., Kennedy D.G., Furey A.: Detection of pyrrolizidine alkaloids in commercial honey using liquid chromatography-ion trap mass spectrometry. Food Chem 2013, 136, 1577–1583.
- Griffin C.T., O’Mahony J., Danaher M., Furey A.: Liquid chromatography tandem mass spectrometry detection of targeted pyrrolizidine alkaloids in honeys purchased within Ireland. Food Anal Methods 2015, 8, 18–31.
- Huybrechts B., Callebaut A.: Pyrrolizidine alkaloids in food and feed on the Belgian market. Food Addit Contam Part A 2015, 32, 1939–1951.
- Kempf M., Beuerle T., Bühringer M., Denner M., Trost D., von der Ohe K., Bhavanam V.B.R., Schreier P.: Pyrrolizidine alkaloids in honey: Risk analysis by gas chromatography-mass spectrometry. Mol Nutr Food Res 2008, 52, 1193–1200.
- Kowalczyk E., Sieradzki Z., Kwiatek K.: Determination of pyrrolizidine alkaloids in honey with sensitive gas chromatography-mass spectrometry method. Food Anal Methods 2018, 11, 1345–1355.
- Lucatello L., Merlanti R., Rossi A., Montesissa C., Capolongo F.: Evaluation of some pyrrolizidine alkaloids in honey samples from the Veneto Region (Italy) by LC-MS/MS. Food Anal Methods 2016, 9, 1825–1836.
- Lucchetti M., Glauser G., Kilchenmann V., Dübecke A., Beckh G., Praz C., Kast C.: Pyrrolizidine alkaloids from Echium vulgare in honey originate primarily from floral nectar. J Agric Food Chem 2016, 64, 5267–5273.
- Martinello M., Borin A., Stella R., Bovo D., Biancotto G., Gallina A., Mutinelli F.: Development and validation of a QuEChERS method coupled to liquid chromatography and high resolution mass spectrometry to determine pyrrolizidine and tropane alkaloids in honey. Food Chem 2017, 234, 295–302.
- Martinello M., Cristofoli C., Gallina A., Mutinelli F.: Easy and rapid method for the quantitative determination of pyrrolizidine alkaloids in honey by ultra-performance liquid chromatography-mass spectrometry: An evaluation in commercial honey. Food Control 2014, 37, 146–152.
- Mulder P.P.J., López Sánchez P., These A., Preiss-Weigert A., Castellari M.: Occurrence of pyrrolizidine alkaloids in food 2015, EFSA:EN–859.
- Mulder P.P.J., de Witte S.L., Stoopen G.M., van der Meulen J., van Wikselaar P.G., Gruys E., Groot M.J., Hoogenboom R.L. Transfer of pyrrolizidine alkaloids from various herbs to eggs and meat in laying hens. Food Addit Contam Part A 2016, 33, 1826–1839.
- Orantes-Bermejo F.J., Serra Bonvehíb J., Gómez-Pajueloc A., Megíasa M., Torresa C.: Pyrrolizidine alkaloids: their occurrence in Spanish honey collected from purple viper’s bugloss Echiumspp). Food Addit Contam Part A 2013, 30, 1799–1806.
- SANTE/11945/2015 Guidance document on analytical quality control and method validation procedures for pesticides residues analysis in food and feed. Supersedes SANCO/12571/2013, Implemented by 01/01/2016, 1–42.
- Statistical manual of AOAC – Association of official analytical chemistry, Edited by Youden W.J., Steiner E.H., Washington 1975, p. 88.
DOI: https://doi.org/10.2478/jvetres-2018-0027 | Journal eISSN: 2450-8608
Language: English
Page range: 173 - 181
Submitted on: Feb 8, 2018
Accepted on: Jun 20, 2018
Published on: Jul 7, 2018
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
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© 2018 Ewelina Kowalczyk, Krzysztof Kwiatek, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.