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The Demographics of Patients with Head and Neck Squamous Cell Carcinoma: a Retrospective Study Cover

The Demographics of Patients with Head and Neck Squamous Cell Carcinoma: a Retrospective Study

Open Access
|Nov 2025

Abstract

Background

Head and neck cancers, primarily squamous cell carcinomas (HNSCC), represent a significant health burden, being localized predominantly on the mucosal surfaces of the head and neck region. Approximately 3% of all cancer cases reported worldwide are attributed to head and neck cancer.

Aim

In this study, we aimed to characterize the demographics and histopathological features of patients with HNSCC.

Material and methods

We reviewed histologically verified cases of HNSCC between 2010 and 2016 from the pathology archive of the County Emergency Hospital, Targu Mures. Data regarding the patients’ age, sex, tumor localization, histopathological type, and grade of differentiation were collected.

Results

The majority of tumors were classic squamous cell carcinomas, with variants and mixed types also identified. The analysis revealed a predominance of male patients, along with a correlation between sex and tumor localization, and an association between age and specific tumor sites.

Conclusions

Our findings underscore the importance of sex, age, and etiological factors in the development and management of HNSCC.

DOI: https://doi.org/10.2478/jim-2024-0003 | Journal eISSN: 2501-8132 | Journal ISSN: 2501-5974
Language: English
Page range: 31 - 34
Submitted on: Dec 7, 2024
Accepted on: Dec 13, 2024
Published on: Nov 28, 2025
Published by: Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Timea Szatmári, Simona Mocan, Zsuzsanna Pap, published by Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.