Acute Fatty Liver of Pregnancy

Lucian Gheorghe Pop; Ioan Dumitru Suciu; Nicolae Suciu; Oana Daniela Toader

doi:10.2478/jim-2020-0001

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Acute Fatty Liver of Pregnancy

Journal of Interdisciplinary Medicine

Volume 5 (2020): Issue 1 (March 2020)

By: Lucian Gheorghe Pop, Ioan Dumitru Suciu, Nicolae Suciu and Oana Daniela Toader

Open Access

|Jun 2020

Abstract

Acute fatty liver of pregnancy (AFLP) is a rare but life-threatening condition that develops in the third trimester of pregnancy. AFLP shares similar clinical features with other more common pregnancy-associated conditions. However, early correct diagnosis is important for maternal and fetal survival. Once the diagnosis has been established, immediate delivery and maternal intensive support should be undertaken. Both parents and the infant should be tested for deficiencies of the mitochondrial fatty acid oxidation, especially for long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency, as many cases of AFLP are related to disruption of this physiological enzymatic pathway.

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Articles in this issue

DOI: https://doi.org/10.2478/jim-2020-0001 | Journal eISSN: 2501-8132 | Journal ISSN: 2501-5974

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Language: English

Page range: 23 - 26

Submitted on: Nov 11, 2019

Accepted on: Feb 10, 2020

Published on: Jun 29, 2020

Published by: Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

acute fatty liver of pregnancy,

long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency,

Swansea criteria,

newborn metabolic screening

Related subjects:

Medicine,

Clinical medicine,

Clinical medicine, other,

Internal medicine,

Internal medicine, other,

Emergency medicine and intensive-care medicine,

Surgery,

Surgery, other

© 2020 Lucian Gheorghe Pop, Ioan Dumitru Suciu, Nicolae Suciu, Oana Daniela Toader, published by Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 5 (2020): Issue 1 (March 2020)