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Proof of concept for DNA storage system with noise-guessing decoder Cover

Proof of concept for DNA storage system with noise-guessing decoder

By:  and    
Open Access
|Oct 2026

Abstract

DNA storage has significant advantages if compared with existing electronic storage systems, usually concentrated in data centers, which form digital cloud infrastructure. These are: longevity, format used by nature, high capacity per volume and small CO2 footprint. Information which is stored and later retrieved from DNA storage systems can be corrupted by insertions, deletions and substitutions (INDELS). Oxford nanopore sequencing is probably the closest to making DNA storage a mass product. On the other hand, different decoding systems based on noise-guessing paradigm also possess advantages when compared with classical error control coding, which has been demonstrated for wide variety of communications channels. Therefore, in this manuscript a proof of concept is given for a DNA storage system with a decoder inspired by the noise-guessing paradigm approach. It is given using a simple model for INDELS obtained from real measured data.

DOI: https://doi.org/10.2478/jee-2026-0050 | Journal eISSN: 1339-309X (formerly 1335-3632) | Journal ISSN: 1335-3632
Language: English
Page range: 529 - 535
Submitted on: Aug 15, 2026
Published online: Oct 11, 2026
Published in print: Oct 1, 2026
Published by: Slovak University of Technology in Bratislava
In partnership with: Paradigm Publishing Services

© 2026 Daniel Hudač, Peter Farkaš, published by Slovak University of Technology in Bratislava
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.