CHD types
| CHD type | n (%) |
|---|---|
| Left-to-right shunt lesions | 25 (18.12) |
| Right-to-left shunt lesions | 41 (30.43%) |
| Obstructive CHD | 32 (23.19%) |
| Complex CHD | 40 (28.99%) |
Univariate and multivariable logistic regression analyses for abnormal TFUS
| Predictor | Univariate logistic regression analysis | Multivariate logistic regression analysis | ||
|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | |
| Positive genetic testing | 4.2 (1.8–9.8) | 0.001 | 3.9 (1.5–10.2) | 0.005 |
| Mechanical ventilation dependence | 3.1 (1.4–6.9) | 0.005 | 2.7 (1.1–6.5) | 0.028 |
| Bethesda high risk | 2.5 (1.2–5.3) | 0.015 | 2.2 (1.0–4.8) | 0.045 |
| Number of associated clinical symptoms | 1.4 (1.1–1.8) | 0.008 | – | – |
| Prostaglandin administration | 2.8 (1.1–7.2) | 0.031 | – | – |
Baseline characteristics of patients
| Variable | Value |
|---|---|
| Demographic characteristics | |
| Sex | |
| Male, n (%) | 70 (50.7%) |
| Female, n (%) | 68 (49.3%) |
| Environment | |
| Urban, n (%) | 43 (31.16%) |
| Rural, n (%) | 95 (68.84%) |
| Postnatal characteristics | |
| Gestational age, weeks (mean ± s.d.) | 36.93 ± 2.59 |
| Prematurity, n (%) | 49 (35.51%) |
| Birth weight, g (mean ± s.d.) | 2,692.55 ± 865.11 |
| Birth length, cm (mean ± s.d.) | 47.7 ± 4.31 |
| Positive genetic testing, n (%) | 37 (26.82%) |
| Genetic syndrome, n (%) | 29 (21.01%) |
| Clinical symptoms | |
| Cardiac murmur, n (%) | 134 (97.10%) |
| Tachycardia, n (%) | 88 (63.77%) |
| Hypoxia, n (%) | 87 (63.04%) |
| Tachypnea, n (%) | 81 (58.70%) |
| Cyanosis, n (%) | 60 (43.48%) |
| Chest wall retraction, n (%) | 66 (47.83%) |
| Arrhythmia, n (%) | 6 (4.35%) |
| Mechanical ventilation dependence, n (%) | 53 (38.41%) |
| Prostaglandin administration, n (%) | 64 (46.38%) |
Transfontanellar ultrasound abnormalities
| Abnormality | n (%) |
|---|---|
| Ventricular dilation | 11 (26.19%) |
| Intraventricular hemorrhage | 7 (16.67%) |
| Choroid plexus cysts | 7 (16.67%) |
| Subependymal hemorrhage | 5 (11.90%) |
| Corpus callosum agenesis (partial/complete) | 6 (14.29%) |
| Cerebral edema | 6 (14.29%) |
| Hydrocephalus | 1 (2.38%) |
| Cerebral aneurysm | 1 (2.38%) |
| Mega cisterna magna | 1 (2.38%) |