Figure 1.
Uni- and multivariable analysis of risk factors associated with death among patients in the case group
| Risk factors | Patients who survived n = 52 | Patients who died n = 79 | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|---|---|
| cOR (95% CI) | p value | aOR (95% CI) | p value | |||
| Aortic dissection | 7 | 8 | 0.72 (0.24–2.13) | 0.55 | – | – |
| Valvulopathy | 17 | 27 | 1.06 (0.5–2.24) | 0.86 | – | – |
| Diabetes mellitus | 2 | 6 | 2.05 (0.39–10.59) | 0.38 | – | – |
| Chronic hypertension | 16 | 20 | 0.76 (0.35–1.65) | 0.49 | – | – |
| Ischemic cardiomyopathy | 4 | 18 | 3.54 (1.12–11.15) | 0.03 | 3.49 (1.97–12.54) | 0.04 |
| Cardiac failure | 12 | 24 | 1.45 (0.65–3.24) | 0.36 | – | – |
| Endocarditis | 3 | 4 | 0.87 (0.18–4.06) | 0.86 | – | – |
| Acute myocardial infarction | 8 | 24 | 2.4 (1.98–5.86) | 0.04 | 2.41 (0.83–6.97) | 0.10 |
| Acute pulmonary edema | 2 | 11 | 4.04 (1.85–19.05) | 0.03 | 2.27 (0.41–12.43) | 0.34 |
| Cardiorespiratory arrest | 7 | 17 | 1.76 (0.67–4.6) | 0.24 | – | – |
| Multidrug-resistant organism | 19 | 60 | 5.48 (2.55–11.78) | 0.0001 | 3.87 (1.53–9.18) | 0.004 |
| Klebsiella pneumoniae | 12 | 32 | 2.26 (1.03–4.98) | 0.041 | 1.24 (0.46–3.36) | 0.66 |
| Acinetobacter baumannii | 3 | 24 | 7.12 (2.02–25.13) | 0.002 | 5.97 (1.53–23.28) | 0.01 |
| Pseudomonas aeruginosa | 4 | 11 | 1.94 (0.58–6.46) | 0.280 | – | – |
| Staphylococcus aureus | 8 | 10 | 0.79 (0.29–2.17) | 0.658 | – | – |
| Longer hospitalization in the ICU | – | – | – | – | 1.03 (0.99–1.078) | 0.11 |
Uni- and multivariable analysis of risk factors associated with death among all patients in the study
| Risk factors | Patients who survived n = 161 (61%) | Patients who died n = 101 (39%) | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|---|---|
| cOR (95% CI) | p value | aOR (95% CI) | p value | |||
| Aortic dissection | 15 | 11 | 1.19 (0.52–2.7) | 0.67 | – | – |
| Valvulopathy | 63 | 28 | 1.59 (1.34–2.02) | 0.04 | 0.68 (0.33–1.37) | 0.28 |
| Diabetes mellitus | 10 | 8 | 1.29 (0.49–3.4) | 0.59 | – | – |
| Chronic hypertension | 38 | 25 | 1.06 (0.59–1.9) | 0.83 | – | – |
| Ischemic cardiomyopathy | 33 | 24 | 1.2 (0.66–2.19) | 0.53 | – | – |
| Cardiac failure | 33 | 29 | 1.56 (0.87–2.78) | 0.12 | – | – |
| Endocarditis | 3 | 4 | 2.17 (0.47–9.91) | 0.31 | – | – |
| Acute myocardial infarction | 15 | 33 | 4.72 (2.4–9.27) | 0.001 | 4.50 (1.92–10.51) | 0.001 |
| Acute pulmonary edema | 4 | 11 | 4.79 (1.48–15.50) | 0.009 | 1.13 (0.27–4.70) | 0.85 |
| Cardiorespiratory arrest | 12 | 23 | 3.66 (1.73–7.74) | 0.001 | 1.64 (0.61–4.44) | 0.32 |
| Multidrug-resistant organism | 19 | 60 | 10.93 (5.87–20.37) | 0.001 | 3.43 (1.31–8.95) | 0.012 |
| Klebsiella pneumoniae | 12 | 32 | 5.75 (2.79–11.85) | 0.001 | 2.01 (0.72–5.66) | 0.18 |
| Acinetobacter baumannii | 3 | 24 | 16.41 (4.79–56.2) | 0.001 | 8.99 (2.21–36.45) | 0.002 |
| Pseudomonas aeruginosa | 4 | 12 | 5.29 (1.65–16.89) | 0.005 | 3.63 (0.89–14.7) | 0.07 |
| Staphylococcus aureus | 8 | 10 | 2.1 (0.8–5.51) | 0.13 | – | – |
| Being part of the case group | 52 | 79 | 7.72 (4.22–13.39) | 0.001 | 1.72 (0.07–3.97) | 0.19 |
Uni- and multivariable analysis of risk factors associated with death among patients in the control group
| Risk factors | Patients who survived n = 109 | Patients who died n = 22 | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|---|---|
| cOR (95% CI) | p value | aOR (95% CI) | p value | |||
| Aortic dissection | 8 | 3 | 1.93 (0.48–8.2) | 0.33 | – | – |
| Valvulopathy | 46 | 1 | 1.21 (1.08–2.23) | 0.04 | 1.12 (1.01–2.00) | 0.04 |
| Diabetes mellitus | 8 | 2 | 1.26 (0.24–6.39) | 0.77 | – | – |
| Chronic hypertension | 22 | 5 | 1.16 (0.38–3.49) | 0.78 | – | – |
| Ischemic cardiomyopathy | 29 | 6 | 1.03 (0.36–2.89) | 0.94 | – | – |
| Cardiac failure | 21 | 5 | 1.23 (0.4–3.72) | 0.71 | – | – |
| Acute myocardial infarction | 7 | 9 | 10.08 (3.21–31.66) | 0.001 | 5.39 (1.14–17.99) | 0.04 |
| Cardiorespiratory arrest | 5 | 6 | 7.8 (2.12–28.57) | 0.02 | 3.89 (0.95–15.92) | 0.059 |