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Transition from ICU to home care with long-term invasive ventilation using a single-limb BiPAP circuit Cover

Transition from ICU to home care with long-term invasive ventilation using a single-limb BiPAP circuit

The Journal of Critical Care Medicine
Volume 12 (2026): Issue 1 (January 2026)
By: Mircea Stoian,  Nicolae Demenciuc,  Sergiu-Stefan Laszlo,  Anca Motataianu,  Dragoș-Florin Babă and  Adina Stoian  
Open Access
|Jan 2026

References

  1. Park S, Suh ES. Home mechanical ventilation: back to basics. Acute Crit Care. 2020 Aug;35(3):131–141.
    Search in Google ScholarBack to article
  2. Nichols NL, Van Dyke J, Nashold L, Satriotomo I, Suzuki M, Mitchell GS. Ventilatory control in ALS. Respir Physiol Neurobiol. 2013 Nov 1;189(2):429–37.
    Search in Google ScholarBack to article
  3. Storre JH, Huttmann SE, Ekkernkamp E, Walterspacher S, Schmoor C, Dreher M, Windisch W. Oxygen supplementation in noninvasive home mechanical ventilation: the crucial roles of CO2 exhalation systems and leakages. Respir Care. 2014 Jan;59(1):113–20.
    Search in Google ScholarBack to article
  4. Ibrahim SG, Silva JM, Borges LG, Savi A, Forgiarini Junior LA, Teixeira C. Use of a noninvasive ventilation device following tracheotomy: an alternative to facilitate ICU discharge? Rev Bras Ter Intensiva. 2012 Jun;24(2):167–72. English, Portuguese.
    Search in Google ScholarBack to article
  5. Maquilón C, Antolini M, Valdés N, Andrade M, Canales K, Rabec C, Olave C, Aguayo M, Rivas P, Andrade C, Venegas Á, Zapata S, Torres ME, Cabrera O, Villalobos J. Results of the home mechanical ventilation national program among adults in Chile between 2008 and 2017. BMC Pulm Med. 2021 Dec 2;21(1):394.
    Search in Google ScholarBack to article
  6. Lloyd-Owen SJ, Donaldson GC, Ambrosino N, Escarabill J, Farre R, Fauroux B, Robert D, Schoenhofer B, Simonds AK, Wedzicha JA. Patterns of home mechanical ventilation use in Europe: results from the Eurovent survey. Eur Respir J. 2005 Jun;25(6):1025–31.
    Search in Google ScholarBack to article
  7. Pinto A, Almeida JP, Pinto S, Pereira J, Oliveira AG, de Carvalho M. Home telemonitoring of non-invasive ventilation decreases healthcare utilisation in a prospective controlled trial of patients with amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 2010 Nov;81(11):1238–42.
    Search in Google ScholarBack to article
  8. Bach JR. Amyotrophic lateral sclerosis: prolongation of life by noninvasive respiratory AIDS. Chest. 2002 Jul;122(1):92–8.
    Search in Google ScholarBack to article
  9. Storre JH, Matrosovich E, Ekkernkamp E, Walker DJ, Schmoor C, Dreher M, Windisch W. Home mechanical ventilation for COPD: high-intensity versus target volume noninvasive ventilation. Respir Care. 2014 Sep;59(9):1389–97.
    Search in Google ScholarBack to article
  10. MacIntyre NR. New modes of mechanical ventilation. Clin Chest Med. 1996 Sep;17(3):411–21.
    Search in Google ScholarBack to article
  11. Tan W, Dai B, Xu DY, Li LL, Li J. In-Vitro Comparison of Single Limb and Dual Limb Circuit for Aerosol Delivery via Noninvasive Ventilation. Respir Care. 2022 Jul;67(7):807–813.
    Search in Google ScholarBack to article
  12. Ibrahim SG, Silva JM, Borges LG, Savi A, Forgiarini Junior LA, Teixeira C. Use of a noninvasive ventilation device following tracheotomy: an alternative to facilitate ICU discharge? Rev Bras Ter Intensiva. 2012 Jun;24(2):167–72. English, Portuguese.
    Search in Google ScholarBack to article
  13. Povitz M, Rose L, Shariff SZ, Leonard S, Welk B, Jenkyn KB, Leasa DJ, Gershon AS. Home Mechanical Ventilation: A 12-Year Population-Based Retrospective Cohort Study. Respir Care. 2018 Apr;63(4):380–387.
    Search in Google ScholarBack to article
  14. Annane D, Orlikowski D, Chevret S. Nocturnal mechanical ventilation for chronic hypoventilation in patients with neuromuscular and chest wall disorders. Cochrane Database Syst Rev. 2014 Dec 13;2014(12):CD001941.
    Search in Google ScholarBack to article
  15. Sancho J, Servera E, Díaz J, Marín J. Efficacy of mechanical insufflation-exsufflation in medically stable patients with amyotrophic lateral sclerosis. Chest. 2004 Apr;125(4):1400–5.
    Search in Google ScholarBack to article
  16. Chatwin M, Toussaint M, Gonçalves MR, Sheers N, Mellies U, Gonzales-Bermejo J, Sancho J, Fauroux B, Andersen T, Hov B, Nygren-Bonnier M, Lacombe M, Pernet K, Kampelmacher M, Devaux C, Kinnett K, Sheehan D, Rao F, Villanova M, Berlowitz D, Morrow BM. Airway clearance techniques in neuromuscular disorders: A state of the art review. Respir Med. 2018 Mar;136:98–110.
    Search in Google ScholarBack to article
  17. Vianello A, Arcaro G, Braccioni F, Gallan F, Marchi MR, Chizio S, et al. Prevention of pulmonary morbidity in patients with neuromuscular disease: Use of mechanical insufflation–exsufflation. Am J Phys Med Rehabil. 2005;84(2):83–88.
    Search in Google ScholarBack to article
  18. Chatwin M, Wakeman RH. Mechanical Insufflation-Exsufflation: Considerations for Improving Clinical Practice. J Clin Med. 2023 Mar 31;12(7):2626.
    Search in Google ScholarBack to article
  19. Kang SW, Bach JR. Maximum insufflation capacity. Chest. 2000 Jul;118(1):61–5.
    Search in Google ScholarBack to article
  20. Koulenti D, Tsigou E, Rello J. Nosocomial pneumonia in 27 ICUs in Europe: perspectives from the EU-VAP/CAP study. Eur J Clin Microbiol Infect Dis. 2017 Nov;36(11):1999–2006.
    Search in Google ScholarBack to article
  21. Torres A, Niederman MS, Chastre J, et al. International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia. Eur Respir J. 2017;50(3):1700582.
    Search in Google ScholarBack to article
  22. Grgurich PE, Hudcova J, Lei Y, Sarwar A, Craven DE. Diagnosis of ventilator-associated pneumonia: controversies and working toward a gold standard. Curr Opin Infect Dis. 2013 Apr;26(2):140–50.
    Search in Google ScholarBack to article
  23. Stoian M, Andone A, Bândilă SR, Onișor D, Laszlo SȘ, Lupu G, Danielescu A, Baba DF, Văsieșiu AM, Manea A, Stoian A. Mechanical Ventilator-Associated Pneumonia in the COVID-19 Pandemic Era: A Critical Challenge in the Intensive Care Units. Antibiotics (Basel). 2025 Jan 3;14(1):28.
    Search in Google ScholarBack to article
  24. Stoian M, Azamfirei L, Andone A, Văsieșiu AM, Stîngaciu A, Huțanu A, Bândilă SR, Dobru D, Manea A, Stoian A. Incidence and Risk Factors of Secondary Infections in Critically Ill SARS-CoV-2 Patients: A Retrospective Study in an Intensive Care Unit. Biomedicines. 2025 May 29;13(6):1333.
    Search in Google ScholarBack to article
  25. Calvo A, Moglia C, Lunetta C, Marinou K, Ticozzi N, Ferrante GD, Scialo C, Sorarù G, Trojsi F, Conte A, Falzone YM, Tortelli R, Russo M, Chiò A, Sansone VA, Mora G, Silani V, Volanti P, Caponnetto C, Querin G, Monsurrò MR, Sabatelli M, Riva N, Logroscino G, Messina S, Fini N, Mandrioli J. Factors predicting survival in ALS: a multicenter Italian study. J Neurol. 2017 Jan;264(1):54–63.
    Search in Google ScholarBack to article
  26. Bourke SC, Tomlinson M, Williams TL, Bullock RE, Shaw PJ, Gibson GJ. Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial. Lancet Neurol. 2006 Feb;5(2):140–7.
    Search in Google ScholarBack to article
  27. Farrero E, Prats E, Povedano M, Martinez-Matos JA, Manresa F, Escarrabill J. Survival in amyotrophic lateral sclerosis with home mechanical ventilation: the impact of systematic respiratory assessment and bulbar involvement. Chest. 2005 Jun;127(6):2132–8.
    Search in Google ScholarBack to article
  28. Stoian M, Andone A, Bândilă SR, Onișor D, Babă DF, Niculescu R, Stoian A, Azamfirei L. Personalized Nutrition Strategies for Patients in the Intensive Care Unit: A Narrative Review on the Future of Critical Care Nutrition. Nutrients. 2025 May 13;17(10):1659.
    Search in Google ScholarBack to article
  29. Farrero E, Prats E, Povedano M, Martinez-Matos JA, Manresa F, Escarrabill J. Survival in amyotrophic lateral sclerosis with home mechanical ventilation: the impact of systematic respiratory assessment and bulbar involvement. Chest. 2005 Jun;127(6):2132–8.
    Search in Google ScholarBack to article
  30. Lechtzin N, Wiener CM, Clawson L, Davidson MC, Anderson F, Gowda N, Diette GB; ALS CARE Study Group. Use of noninvasive ventilation in patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord. 2004 Mar;5(1):9–15.
    Search in Google ScholarBack to article
  31. Cazzolli PA, Oppenheimer EA. Home mechanical ventilation for amyotrophic lateral sclerosis: nasal compared to tracheostomy-intermittent positive pressure ventilation. J Neurol Sci. 1996 Aug;139 Suppl:123–8.
    Search in Google ScholarBack to article
  32. Benditt JO, Boitano LJ. Pulmonary issues in patients with chronic neuromuscular disease. Am J Respir Crit Care Med. 2013 May 15;187(10):1046–55.
    Search in Google ScholarBack to article
  33. Bach JR, Gonçalves MR, Hamdani I, Winck JC. Extubation of patients with neuromuscular weakness: a new management paradigm. Chest. 2010 May;137(5):1033–9.
    Search in Google ScholarBack to article
  34. Nava S, Sturani C, Hartl S, Magni G, Ciontu M, Corrado A, Simonds A; European Respiratory Society Task Force on Ethics and decision-making in end stage lung disease. End-of-life decision-making in respiratory intermediate care units: a European survey. Eur Respir J. 2007 Jul;30(1):156–64.
    Search in Google ScholarBack to article
  35. Windisch W, Walterspacher S, Siemon K, Geiseler J, Sitter H; German Society for Pneumology. Guidelines for non-invasive and invasive mechanical ventilation for treatment of chronic respiratory failure. Published by the German Society for Pneumology (DGP). Pneumologie. 2010 Oct;64(10):640–52.
    Search in Google ScholarBack to article
  36. Gonzalez-Bermejo J, Perrin C, Janssens JP, Pepin JL, Mroue G, Léger P, Langevin B, Rouault S, Rabec C, Rodenstein D; SomnoNIV Group. Proposal for a systematic analysis of polygraphy or polysomnography for identifying and scoring abnormal events occurring during non-invasive ventilation. Thorax. 2012 Jun;67(6):546–52.
    Search in Google ScholarBack to article
  37. Huttmann SE, Windisch W, Storre JH. Invasive home mechanical ventilation: living conditions and health-related quality of life. Respiration. 2015;89(4):312–21.
    Search in Google ScholarBack to article
  38. White AC. Long-term mechanical ventilation: management strategies. Respir Care. 2012 Jun;57(6):889–97; discussion 898–9.
    Search in Google ScholarBack to article
DOI: https://doi.org/10.2478/jccm-2026-0004 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Journal RSS Feed
Language: English
Page range: 117 - 124
Submitted on: Aug 22, 2025
|
Accepted on: Nov 12, 2025
|
Published on: Jan 30, 2026
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
amyotrophic lateral sclerosis,
non-invasive ventilation,
invasive mechanical ventilation,
mechanical insufflation-exsufflation device,
respiratory failure,
home mechanical ventilation,
respiratory muscles
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Internal medicine, other,
Surgery,
Surgery, other,
Anaesthesiology,
Emergency medicine and intensive-care medicine

© 2026 Mircea Stoian, Nicolae Demenciuc, Sergiu-Stefan Laszlo, Anca Motataianu, Dragoș-Florin Babă, Adina Stoian, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.

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