Postoperative Outcomes
| Parameter | MG Group | Control Group | p-value | Statistical Test |
|---|---|---|---|---|
| Atrial Fibrillation | 12 (18.5%) | 27 (41.5%) | 0.007 | Multivariable logistic regression (adjusted for age, EF) |
| ICU Stay (days) | 2.1 ± 0.8 | 3.5 ± 1.2 | <0.001 | ANCOVA (adjusted for surgery type) |
| Hospital Stay (days) | 6.2 ± 1.5 | 7.8 ± 2.1 | <0.001 | ANCOVA (adjusted for age, EF) |
| Ventilation Time (hrs) | 8.4 ± 3.1 | 11.6 ± 4.3 | <0.001 | Quantile regression (median) |
| Renal Impairment | 4 (6.2%) | 9 (13.8%) | 0.12 | Generalized linear model (log-binomial) |
| Rebleeding | 5 (7.7%) | 9 (13.8%) | 0.24 | Fisher’s exact test |
| Open chest | 3 (4.6%) | 5 (7.7%) | 0.47 | Fisher’s exact test |
| Stroke | 1 (1.5%) | 2 (3.1%) | 0.56 | Fisher’s exact test |
| Hypotension (SBP <90 mmHg) | 8 (12.3%) | 10 (15.4%) | 0.61 | Chi-square |
| Magnesium Levels Over Time | ||||
| Timepoint | MG Group (mg/dL) | Control Group (mg/dL) | p-value | Statistical Test |
| Post-CPB | 2.8 ± 0.4 | 1.9 ± 0.3 | <0.001 | Linear mixed-effects model |
| ICU Arrival | 3.1 ± 0.5 | 2.0 ± 0.4 | <0.001 | Linear mixed-effects model |
| 24 Hours Post-Op | 3.4 ± 0.6 | 2.1 ± 0.5 | <0.001 | Linear mixed-effects model |
| Subgroup Analysis by Surgery Type | ||||
| Surgery Type | AF Incidence (MG) | AF Incidence (Control) | Adjusted OR (95% CI) | p-value |
| CABG | 10/50 (20.0%) | 22/53 (41.5%) | 0.35 (0.15–0.82) | 0.01 |
| AVR | 1/8 (12.5%) | 3/6 (50.0%) | ||
| MVR | 1/5 (20.0%) | 2/4 (50.0%) | ||
| AVR/MVR Pooled | 2/13 (15.4%) | 5/10 (50.0%) | 0.22 (0.04–1.25) | 0.09 |
| Combined | 0/2 (0%) | 0/2 (0%) | ||
Interaction Effects on AF Risk
| Subgroup | Adjusted OR (95% CI) | p-value | Interaction p-value |
|---|---|---|---|
| Age ≥60 vs. <60 | 0.35 (0.14–0.87) | 0.02 | 0.21 |
| Diabetes vs. No DM | 0.41 (0.19–0.91) | 0.03 | 0.45 |
| CABG vs. Valve | 0.38 (0.15–0.94) | 0.04 | 0.18 |