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Comparative analysis of outcomes between anemic and non-anemic critically ill elderly patients in a geriatric ICU in Egypt: A focused study Cover

Comparative analysis of outcomes between anemic and non-anemic critically ill elderly patients in a geriatric ICU in Egypt: A focused study

Open Access
|Jul 2025

Figures & Tables

Fig. 1.

Description of grades of anemia among studied subjects
Description of grades of anemia among studied subjects

Fig. 2.

Rate of decline of hemoglobin level among studied subjects
Rate of decline of hemoglobin level among studied subjects

Fig. 3.

Management of anemia among studied subjects
Management of anemia among studied subjects

Comparison between anemic and non-anemic groups as regard hemodynamic support, mechanical ventilation and outcomes

Anemic (n=172) (Mean±SD) (±SEM)Non anemic (n=44) (Mean±SD) (±SEM)Student’s “t”/ZP(sign.)
Outcomes:
Length of stay (LOS)(Days)8.42±0.467.68±0.97“t”= 0.710.04 <0.05(S)

Description of outcomes among studied patients

OutcomesAll patients (n=216)%
In hospital mortality (30 day mortality)9443.5

Linear regression analysis for factors affecting of mortality in ICU

Unstandardized BCoefficients Std. ErrorStandardized Coefficients BetatP-value (Sign.)
Age0.0060.0040.0881.510.13(NS)
Smoking0.1130.0440.1462.530.012(S)
Previous ICU admission−0.0060.069−0.005−0.080.93(NS)
Anemia(past history)−0.1440.085−0.10−1.680.09(NS)
Anemia on admission0.1370.0920.1111.480.14(NS)
Grades of anemia−0.60.04−0.124−1.450.14(NS)
Hospital acquired anemia0.1000.1170.0640.850.39(NS)
Mechanical ventilation0.330.0920.243.620.00(HS)
Vasopressor0.1750.090.141.940.05(S)
Blood transfusion0.1840.070.172.480.01(S)
CRP0.0010.000.122.190.02(S)
Platelets0.000.000.143−2.880.00(HS)
MPM72 hours0.010.0050.442.070.04(S)

Demographics, premorbid comorbidities and Charsoln comorbidity index among studied subjects (n=216)

Quantitative:Mean±SDRange
Age(yrs)75.00±7.8460–98

Comparison between anemic and non-anemic groups as regard age, sex, severity of illness and predictors of mortality tools

Anemic (n=172) (Mean+SD) (+SEM)Non anemic (n=44) (Mean+SD) (+SEM)Student’s “t”/ZP (Sign.)
Age (yrs)74.99+7.7875.05+8.15“t”= 0.04(0.97) >0.05(NS)

Comparison between anemic and non-anemic as regard Comorbidity data and Charlson Comorbidity index

ComorbiditiesAnemic (n=172) No (%)Non-anemic (n=44) No(%)X2P(Sign)
Neurological diseases149(83.1%)10(16.9%)4.23(0.44)>0.05(NS)
Hypertension101(61.5%)21(17.2%)1.72(0.18)>0.05(NS)
Pulmonary diseases128(90.3%)3(9.7%)2.55(0.11)>0.05(NS)
COVID 19 infection10(76.9%)3(23.1%)0.06(0.8)>0.05(NS)
Diabetes Mellitus67 (81.7%)15(18.3%)0.35(0.55)>0.05(NS)
Cardiac disease369 (82.1%)15 (17.9%)0.53(0.46)>0.05(NS)
Renal disease435 (92.1%)3 (7.9%)4.42(0.03)<0.05(S)
Hepatic diseases523(88.5%)3(11.5%)1.42(0.23)>0.05(NS)
Premorbid Anemia30(96.8%)1(3.2%)6.55(0.01)<0.05(S)
Dementia56 (76.7%)17 (23.3%)0.57(0.44)>0.05(NS)
Malignancy29(90.6%)3(9.4%)2.80(0.09) >0.05(NS)
Previous ICU admission47(94%)3(6%)8.28(0.004)<0.05(S)

Charlson Comorbidity Index
<7105(75%)35(25%)5.25(0.02)<0.05(S)
>767(88.2%)9(11.8%)
DOI: https://doi.org/10.2478/jccm-2025-0028 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 290 - 300
Submitted on: Nov 6, 2024
Accepted on: Jun 25, 2025
Published on: Jul 31, 2025
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Manar Mamdouh Abd Al Kader, Manar Mostafa Adel Maamoun, Walaa W. Aly, Heba Youssif Youssif, Mennatallah Safwat Elaraby, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.