Have a personal or library account? Click to login
Comparative assessment of hemodynamic changes and outcomes in ventilator weaning Cover

Comparative assessment of hemodynamic changes and outcomes in ventilator weaning

Open Access
|Jul 2025

Figures & Tables

Fig. 1.

Intercomparison of hemodynamic parameters between the VTI, SV, and CO. CO: cardiac output; SV: stroke volume; TEE: transesophageal echocardiography; TTE: transthoracic echocardiography; VCV: volume-controlled ventilation; VPS: variable pressure support; VTI: velocity time integral
Intercomparison of hemodynamic parameters between the VTI, SV, and CO. CO: cardiac output; SV: stroke volume; TEE: transesophageal echocardiography; TTE: transthoracic echocardiography; VCV: volume-controlled ventilation; VPS: variable pressure support; VTI: velocity time integral

Analysis of TTE and TEE

Ventilation modeParameterTEE (mean ± S.D)TTE (mean ± S.D)p-value
VCVVTI21.11±3.0321.30±3.080.313
SV65.95±17.6665.95±17.371

PSVTI19.65±2.4819.33±2.740.202
SV61.58±17.8760.45±18.540.356

VPSVTI18.30±3.0718.53±2.950.108
SV57.93±19.7358.48±19.880.079

The Outcomes Statistics of the hemodynamic assessment between the two arms

OutcomesArm-A (VPS group)Arm-B (PS group)p-value
Ventilator days (mean ± S.D)9.05± 4.569.30± 5.970.882
Length of stay (mean ± S.D)16.20±6.9217.25±7.640.651

Weaning trialYes (n, %)12 (60%)10 (50%)0.525
No (n, %)8 (40%)10 (50%)

SurvivalYes (n, %)10 (50%)8 (40%)0.525
No (n, %)10 (50%)12 (60%)

Inter-statistical comparison between the three modes in both arms

ParameterVCV (mean ± SD)VPS (mean ± SD)p-value
TEE VTI21.11±3.0318.30±3.070.02
TTE VTI21.30±3.0818.53±2.950.04
TEE SV65.95±17.6657.93±19.730.03
TTE SV65.95±17.3758.48±19.880.05
CO5.57±1.544.83±1.580.01

ParameterVCV (mean ± S.D)PS (mean ± S.D)p-value
TEE VTI21.11±3.0319.65±2.480.04
TTE VTI21.30±3.0819.33±2.740.05
TEE SV65.95±17.6661.58±17.870.03
TTE SV65.95±17.3760.45±18.540.02
CO5.57±1.545.18±1.500.04

ParameterVPS (mean ± S.D)PS (mean ± S.D)p-value
TEE VTI18.30±3.0719.65±2.480.004
TTE VTI18.53±2.9519.33±2.740.05
TEE SV57.93±19.7361.58±17.870.002
TTE SV58.48±19.8860.45±18.540.059
CO4.83±1.585.18±1.500.04

Patient characteristics and data during the study

DataArm-A (VPS group)Arm-B (PS group)p-value
GenderMale13 (65%)13 (65%)1
Female7 (35%)7 (35%)

Co-morbidities
Hypertension13 (65%)8 (40%)0.113
Diabetes Mellitus10 (50%)4 (20%)0.047
Chronic Kidney Diseases2 (10%)5 (25%)0.407
Ischemic Heart disease4 (20%)3 (15%)1
Chronic obstructive pulmonary disease3 (15%)2 (10%)1

Clinical Data (mean± S.D)
HR88.35±19.98882.65±13.550.298
MAP73.40±7.7670.20±7.170.183

Echocardiographic Data (mean± S.D)
LVOT diameter (cm)2.05±0.331.93±0.300.20
TEE VTI (VCV)20.50±2.7421.70±3.260.223
TTE VTI (VCV)20.50±2.9122.10±3.110.101
TEE SV (VCV)67.95±18.6363.95±16.870.481
TTE SV (VCV)68.00±18.1763.90±16.740.463
CO (VCV)5.74±1.345.39±1.730.473
DOI: https://doi.org/10.2478/jccm-2025-0022 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 265 - 274
Submitted on: Jan 15, 2025
Accepted on: May 10, 2025
Published on: Jul 31, 2025
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Dina Zeid Roushdy, Hossam Ahmed Saad, Randa Aly Soliman, Mohammed Aly Shehata, Mohammed Amin Fakhir, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.