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What proteins and albumins in bronchoalveolar lavage fluid and serum could tell us in COVID-19 and influenza acute respiratory distress syndrome on mechanical ventilation patient - A prospective double center study Cover

What proteins and albumins in bronchoalveolar lavage fluid and serum could tell us in COVID-19 and influenza acute respiratory distress syndrome on mechanical ventilation patient - A prospective double center study

Open Access
|Jan 2025

Figures & Tables

Fig. 1.

Mechanical ventilation days of ARDS (median, IQR) divided by groups
Mechanical ventilation days of ARDS (median, IQR) divided by groups

Fig 2.

Comparison of ARDS patient outcomes between COVID-19 and H1N1 concerning mechanical ventilation duration.
Comparison of ARDS patient outcomes between COVID-19 and H1N1 concerning mechanical ventilation duration.

Proteins and albumins values between the patient group and outcomes

COVID-19 group (mean±SD)H1N1 group (mean±SD)Control group (mean±SD)p*Survivors (mean±SD)Deceased (mean±SD)p**
BAL albumin (g/L)1.63±1.351.55±1.460.07±0.07<0.0010.58±1.111.71±1.34<0.001
BAL total protein (g/L)1.53±0.711.47±0.710.43±0.35<0.0010.85±0.711.52±0.72<0.001
Serum albumin (g/L)28.73±4.9731.93±4.8538.43±4.03<0.00136.09±5.1728.61±4.89<0.001

Demographic variables, days of invasive mechanical ventilation and outcome between two groups of ARDS patients

COVID-19 groupH1N1 groupp*SurvivorsDeceasedp**
Patients (n)3014NA13 (29.5%)31(70.5%)NA
Age (median, IQR)72.5 (35–83)62 (34–69)<0.0160 (35–70)72 (34–83)<0.01
Male (n,%)17 (56.7%)7(50%)0.79 (37.5%)15 (62.5%)0.24
COPD (n,%)3 (10%)3 (21.4%)0.431 (16.7%)5 (83.3%)0.57
CV diseases (n,%)18 (60%)6 (42.9%)0.336 (25%)18 (75%)0.51
Diabetes (n,%)6 (20%)2 (14%)0.711 (12.5%)7 (87.5%)0.35
CMV days (median, IQR)13 (1–31)14 (1–34)0.2713 (1–39)13 (1–39)0.5
Survivors (n,&)5 (16.7%)8 (57.1%)<0.01NANANA
DOI: https://doi.org/10.2478/jccm-2025-0005 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 64 - 69
Submitted on: Mar 8, 2024
Accepted on: Jan 8, 2025
Published on: Jan 31, 2025
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Anita Djurdjevic Svraka, Dragan Svraka, Bosa Mrjanic Azaric, Jovana Malic, Goran Baric, Pedja Kovacevic, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.