Fig. 1.
![Brain MRI. Axial diffusion weighted image (A), ADC map (B), T1 SE post-contrast (C), and T2*-GRE (D), demonstrating signs of ventriculitis manifested by an increase in dimensions and ‘tension’ of the walls in the occipital and temporal horns of the ventricular system [C, blue arrows]. Content with restricted diffusion and a liquid level in the occipital horns: indicating purulent content [A–B: red arrow]. There is no significant blooming in T2* suggestive of hemorrhage [D].](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/6677f513dd1c3d1f8713e08e/j_jccm-2024-0020_fig_001.jpg?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Credential=AKIA6AP2G7AKOUXAVR44%2F20251208%2Feu-central-1%2Fs3%2Faws4_request&X-Amz-Date=20251208T134819Z&X-Amz-Expires=3600&X-Amz-Signature=696ad8604ba16c74f3014274af6f944b985ca240e2e8230979a476053c28ac18&X-Amz-SignedHeaders=host&x-amz-checksum-mode=ENABLED&x-id=GetObject)
Fig. 2.
![Brain MRI. Axial diffusion weighted image (A), ADC map (B), T2/FLAIR (fluid-attenuation-inversion-recovery) (C) and T1 SE post contrast (D), showing increased signal in T2iFLAIR image at the adjacent bilateral periventricular parenchyma [C, blue arrows], with restricted diffusion [A-B] and anomalous contrast enhancement [D], exhibiting signs of loculation in the right parietal white matter [D, yellow arrow] and some focal contralateral nodules [I), red arrows].](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/6677f513dd1c3d1f8713e08e/j_jccm-2024-0020_fig_002.jpg?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Credential=AKIA6AP2G7AKOUXAVR44%2F20251208%2Feu-central-1%2Fs3%2Faws4_request&X-Amz-Date=20251208T134819Z&X-Amz-Expires=3600&X-Amz-Signature=bcf2e9189e91e61adc5cfea5138e7d4e3d927a234b736378a97535d8abdb9489&X-Amz-SignedHeaders=host&x-amz-checksum-mode=ENABLED&x-id=GetObject)
Fig. 3.
Evolution of Pseudomonas Aeruginosa susceptibility testing_
| Antibiogram | CSF (day 25) | BRS (day 25) | BRS (day 48) |
|---|---|---|---|
| Piperacillin-tazobactam | R | R | R |
| Amikacin | - | - | - |
| Aztreonam | R | R | R |
| Cefepime | R | R | SIE |
| Ceftazidime | R | R | R |
| Ciprofloxacin | R | R | R |
| Imipenem | R | R | R |
| Meropenem | R | R | R (>32 mg/l) |
| Tobramycin | S | S | S |
| Levofloxacin | R | R | R |
| Colistin | S | S (1.0 mg/l) | S (2.0 mg/l) |
| Ceftazidime-avibactam | R | R | R (>256 mg/l) |
| Ceftolozane-tazobactam | S | S | R |
| Imipenem-cilastin-relebactam | R (6.0 mg/l) | R | R (4.0 mg/l) |
| Meropenem-varobactam | - | - | - |