Fig. 1.
Statistical analysis of the patient's risk factors according to their gender
| Variables | p-value | OR(CI95%) |
|---|---|---|
| Gender | 0.23 | 0.348 to 1.294 |
| Intubation time | 0.09 | 0.989 to 1.000 |
| Ischemia time | 0.93 | 0.986 to 1.012 |
| CPB time | 0.43 | 0.994 to 1.012 |
Detailed clinical and baseline characteristics of research participants
| Variables | Total (101) | Female (35) | Male (66) | OR(CI95%) | p-value |
|---|---|---|---|---|---|
| In-hospital mortality | 41 (40.6) | 16 (45.7) | 25 (37.9) | 0.72 (0.31–1.66) | 0.290* |
| Immediate mortality | 11 (10.9) | 6 (9.1) | 5 (14.3) | 0.6 (0.16–2.12) | 0.315* |
| Renal dysfunction | 53 (52.5) | 37 (56.1) | 16 (45.7) | 1.51 (0.66–3.45) | 0.217* |
| Hemofiltration | 15 (14.9) | 9 (13.6) | 6 (17.1) | 0.76 (0.24–2.35) | 0.770* |
| Hemopericardium | 35 (34.7) | 16 (24.2) | 19 (54.3) | 0.26 (0.11–0.64) | 0.003* |
| Cardiac tamponade | 14 (13.9) | 9 (13.6) | 5 (14.3) | 0.94 (0.29–3.08) | 0.575* |
| Cardiogenic shock | 11 (10.9) | 6 (9.1) | 5 (14.3) | 0.60 (0.16–2.12) | 0.315* |
| Systemic hypertension | 74(73.3) | 44 (66.7) | 30 (85.7) | 0.33 (0.11–0.97) | 0.031* |
| Myocardial infarction | 2 (2) | 1 (1.5) | 1 (2.9) | 0.52 (0.32–8.62) | 0.575* |
| Cardiac arrest | 2 (2) | 1 (1.5) | 1 (2.9) | 0.52 (0.32–8.62) | 0.575* |
| Pulmonary hypertension | 3 (3) | 0 (0) | 3 (8.6) | 0.32 (0.24–0.43) | 0.039* |
| Chronic obstructive pulmonary disease | 8 (7.9) | 6 (9.1) | 2 (5.7) | 1.65 (0.31–8.64) | 0.431* |
| Asthma | 3 (3) | 2 (3) | 1 (2.9) | 1.06 (0.09–12.1) | 0.725* |
| pre-op Inotropes therapy | 12 (11.9) | 9 (13.6) | 2 (8.6) | 1.16 (0.42–6.67) | 0.536* |
| Dopamine | 3 (3) | 2 (3) | 1 (1.29) | 1.06 (0.09–12.14) | 0.725* |
| Dobutamine | 7 (6.9) | 5 (7.6) | 2 (5.7) | 1.35 (0.24–7.35) | 0.539* |
| Adrenaline | 2 (2) | 1 (1.5) | 1 (2.9) | 0.52 (0.32–8.62) | 0.575* |
| Noradrenaline | 7 (6.9) | 7 (10.6) | 0 (0) | 0.62 (0.53–0.73) | 0.045* |
| peri-op Inotropes therapy | 40 (39.6) | 24 (36.4) | 16 (45.7) | 1.47 (0.64–2.29) | 0.398* |
| Dopamine | 63 (62.4) | 44 (66.7) | 19 (54.3) | 0.59 (0.25–1.37) | 0.281* |
| Dobutamine | 79 (78.2) | 47 (71.2) | 32 (91.4) | 4.31 (1.17–15.78) | 0.015* |
| Adrenaline | 86 (85.1) | 54 (81.8) | 32 (91.4) | 2.37 (0.62–9.04) | 0.159* |
| Noradrenaline | 53 (52.5) | 34 (51.5) | 19 (54.3) | 1.11 (0.49–2.54) | 0.478* |
| post-op Inotropes therapy | 47 (46.5) | 30 (45.5) | 17 (48.6) | 1.13 (0.49–2.57) | 0.464* |
| Dopamine | 66 (65.3) | 47 (71.2) | 19 (54.3) | 0.48 (0.20–1.12) | 0.070* |
| Dobutamine | 75 (74.3) | 47 (71.2) | 28 (80.0) | 1.61 (0.60–4.32) | 0.237* |
| Adrenaline | 82 (81.2) | 54 (81.8) | 28 (80.0) | 0.88 (0.31–2.51) | 0.511* |
| Noradrenaline | 61 (60.4) | 39 (59.1) | 22 (62.9) | 1.17 (0.50–2.72) | 0.440* |
Age characteristics of research participants
| Age | Total n=/% | Female n=/% | Male n=/% | p-value |
|---|---|---|---|---|
| <50 | 12 (11.9%) | 2 (5.7%) | 10 (15.2%) | 0.28 |
| 51–60 | 17 (16.8%) | 5 (14.3%) | 12 (18.2%) | 0.82 |
| 61–70 | 43 (42.6%) | 12 (34.3%) | 31 (47.0%) | 0.30 |
| 71–80 | 29 (28.7%) | 16 (45.7%) | 13 (19.7%) | 0.01 |
Laboratory data of patients
| Variables | Total (n=101) | Female (n=35) | Male (n=66) | p-value |
|---|---|---|---|---|
| Age | 64.30 (+/−10.4) | 68.31 (+/9.49) | 62.17 (+/10.39) | 0.004* |
| Ejection fraction | 52 (+/−6.5) | 51 (+/−6.65) | 52 (+/−6.47) | 0.58* |
| Creatinine at admission | 1.16 (+/−0.44) | 1.08 (+/−0.39) | 1.21 (+/−0.45) | 0.17* |
| eGFR at admission | 71.30 (+/−23.4) | 63.20 (+/−21.2) | 75.59 (+/−23.53) | 0.009* |
| Creatinine 1 day in the ICU | 1.45 (+/−0.99) | 1.08 (+/−0.39) | 1.40 (+/−0.9) | 0.994* |
| eGFR in the ICU | 64.7 (+/−28.62) | 54.63 (+/−26.57) | 70.07 (+/−25.5) | 0.024* |
| Creatinine at discharge | 1.31 (+/−1.05) | 1.47 (+/−1.48) | 1.23 (+/−0.74) | 0.638* |
| eGFR at discharge | 72.29 (+/−28.25) | 61.80 (+/−27.34) | 77.85 (+/−27.31) | 0.006* |
| Ischemia time | 135.65 (+/−48.31) | 131.17 (+/−47.1) | 138.03 (+/−49.1) | 0.50* |
| Total bypass time | 201.73 (+/−73.35) | 188.77 (+/−67.9) | 208.61 (+/−75.6) | 0.19* |
| Days in the ICU | 1 (0–34) | 2 (0–21) | 1 (0–34) | 0.88** |
| Intubation time | 10 (1–792) | 2 (0–21) | 11 (1–792) | 0.19** |