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Pharmacokinetics of Teicoplanin in a Patient with Coronavirus Disease 2019 Receiving Veno-venous Extracorporeal Membrane Oxygenation Cover

Pharmacokinetics of Teicoplanin in a Patient with Coronavirus Disease 2019 Receiving Veno-venous Extracorporeal Membrane Oxygenation

Open Access
|Nov 2022

Figures & Tables

Fig. 1

Time course of teicoplanin (TEIC) concentration in the blood after administering the maintenance dose of 600 mg TEIC every 24 h. Blood was collected from the radial artery (black) and pre-oxygenator site (blue) and post-oxygenator (red) site.
Time course of teicoplanin (TEIC) concentration in the blood after administering the maintenance dose of 600 mg TEIC every 24 h. Blood was collected from the radial artery (black) and pre-oxygenator site (blue) and post-oxygenator (red) site.

Blood test results at admission

TestsResults
Complete blood count
WBC9,200/μL
Neut81%
Ly12.5%
Hb15.3 g/dL
Hct44.3%
Plt
217 × 103/μL
Blood coagulation
PT125%
APTT33.2 s
Fibrinogen535 mg/dL
FDP5.7 μg/mL
D-dimer1.9 μg/mL
AT III98%
TAT
11.1 ng/mL
Blood biochemistry
AST86 U/L
ALT34 U/L
LDH833 U/L
TP5.5 g/dL
Alb2.7 g/dL
BUN48 mg/dL
Cr0.77 mg/dL
Na139 mEq/L
K3.9 mEq/L
Cl104 mEq/L
CK136 U/L
Ferritin882.1 ng/dL
CRP3.6 mg/dL
PCT
0.3 ng/mL
Blood gas (oxygen mask with reservoir and oxygen flow set at 15 L/min)
pH7.489
PaCO229.9 Torr
PaO262.3 Torr
HCO322.5 mEq/L
BE0.7 mEq/L
SatO291.9%
Lac1.2 mmol/L
DOI: https://doi.org/10.2478/jccm-2022-0021 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 288 - 291
Submitted on: Aug 11, 2021
|
Accepted on: Aug 30, 2022
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Published on: Nov 12, 2022
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2022 Nobuhisa Hirayu, Atsuo Nakamura, Toshio Morita, Osamu Takasu, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.