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Acute Kidney Injury Following Rhabdomyolysis in Critically Ill Patients Cover

Acute Kidney Injury Following Rhabdomyolysis in Critically Ill Patients

Open Access
|Nov 2021

Figures & Tables

Table 1

Patient’s demographic data, length of stay, SOFA Score, comorbid and serum creatinine kinase levels. Values are shown as mean (SD) or median (interquartile range) and number (percentage).

Non-acute kidneyAcute kidney injuryp-value
injury (n=95)(n=54)
Gender
Male74(77.9%)41(75.9%)0.783
Female21(22.1%)13(24.1%)
Ethnicity
Malay54(56.8%)26(48.1%)
Chinese19(20.9%)14(25.9%)0.859
Indian14(14.7%)9(16.7%)
Others8(8.4%)5(9.3%)
Age, Mean (SD) years43.3(18.6)46.8(15.5)
<4045(47.4%)20(37.0%)
41-6031(32.6%)22(40.7%)0.238
>6119(20.0%)12(22.2%)
Weight, kg70[63-80]80[70-86.8]
<5010(10.5%)0<0.001*
51-7025(26.3%)12(22.5%)
>7160(63.2%)42(77.8%)
Length of Stay in ICU (days)5[2-8]5[3-11.25]0.210
SOFA score, Mean (SD)5.8(3.7)10.7(4.3)
≤218(18.9%)2(3.7%)<0.001*
>277(81.1%)52(96.3%)
Comorbidities
Diabetes17(17.9%)17(31.5%)0.057
Asthma7(7.4%)3(5.6%)0.748
Hypertension21(22.1%)19(35.2%)0.083
Creatinine kinase level on upon diagnosis of rhabdomyolysis2179[1246-4742]2065[796-7741]0.435
Creatinine kinase level post-treatment1578[661-2374]2030[764-5548]0.048*
Time taken to reach the highest creatinine kinase (days)2[1-2]2[1-3]0.260
Mortality4(4.2%)19(35.2%)<0.001*

[i] *p less than 0.05 is significant

Table 2

Bivariate analysis of associated risk factors in Acute Kidney Injury development expressed as mean (SD), number (%), median [IQR] as appropriate.

LoweUpper
Weight >50 kg1.0401.0161.064<0.001*
SOFA score (>2)1.3721.2231.539<0.001*
Antipsychotics2 (2.1%)1 (1.9%)0.702
Sepsis15 (15.8%)27 (50%)5.3332.47611.487<0.001*
Prolonged Surgery17 (17.9%)8 (14.7%)0.658
Trauma46 (48.4%)17 (31.5%)0.4890.2430.9870.046
Hyperthermia01 (1.9%)0.362

* p less than 0.05 is significant

* p less than 0.05 is significant

* p less than 0.05 is significant

Table 3

Multivariate logistic regression of risk factors developing Acute Kidney Injury in rhabdomyolysis patients.

LowerUpper
Weight (>50 kg)1.0341.0061.0630.016*
Sofa Score (>2)1.2991.1511.467<0.001*
Sepsis2.4750.9786.261<0.05*

* p less than 0.05 is significant

* p less than 0.05 is significant

* p less than 0.05 is significant

DOI: https://doi.org/10.2478/jccm-2021-0025 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 267 - 271
Submitted on: Mar 30, 2021
Accepted on: Jun 30, 2021
Published on: Nov 6, 2021
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2021 Alvin Saverymuthu, Rufinah Teo, Jaafar Md Zain, Saw Kian Cheah, Aliza Mohamad Yusof, Raha Abdul Rahman, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.