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Ischemic Stroke in Patients with Cancer: A Retrospective Cross-Sectional Study Cover

Ischemic Stroke in Patients with Cancer: A Retrospective Cross-Sectional Study

Open Access
|Jan 2021

Figures & Tables

Multivariate logistic regression analysis

p-value95%C.I.for EXP(B)
LowerUpper
Cholesterol0.0001.0021.008
Triglycerides0.8190.9971.002
Thrombocytes0.1841.0001.000
Diabetes mellitus0.0011.3573.563
Hypertension history0.0000.0260.057
Smoking history0.0060.2160.777
Alcohol history0.1930.3951.207
AF0.1490.8732.444

Characteristics of the study patients according to the cardiovascular risk factors, stroke aetiology based on TOAST classification and cerebral territory involved based on the OCSP criteria_

SAC (N=249)SWC (N=1563)P-value
Risk factors
Hypertension history (Y: N)196:531464:99<0.01
Smoking history (Y: N)48:177376:11870.36
Alcohol consumption history (Y: N)46:176394:11690.14
Diabetes mellitus (Y:N)48:201242:1321<0.01
AF (Y: N)60:189257:1306<0.01
Seizures (Y: N)11:23838:15250.07
TOAST classification
Large artery atherosclerosis70669<0.01
Small vessel disease412240.92
Cardioembolic603060.01
Other known cause6480.56
Cryptogenic cause72143<0.01
OCSP classification
TACI403000.04
PACI1356910.23
POCI582980.55
LACI6331.00

Primary cancer location in stroke patients

Affected organNr.%
Colon239.24%
Haematological208.03%
Breast218.43%
Urinary bladder228.84%
Prostate239.24%
Lung4819.28%
Pancreas114.42%
Skin72.81%
Gynaecological-related208.03%
Gastric135.22%
Ear-nose-throat-related187.23%
Renal93.61%
Thyroid62.41%
Other organs83.21%

Demographical, clinical and laboratory characteristics of stroke patients with cancer and without cancer

SAC (N=249)SWC (N=1563)P-value
Age71.70(9.98)70.24(12.473)0.08
Gender (M: F)155:94807:756<0.01
Hospitalization days10.07(5.219)10.72(7.497)0.19
NIHSS on admission6.41(5.274)4.93(5.398)<0.01
GCS on admission14.73(1.143)14.64(1.593)0.48
mRS at discharge2.66(1.492)2.21(2.299)<0.01
SBP on admission159.86(29.756)148.63(32.376)<0.01
DBP on admission89.35(17.805)85.44(16.395)<0.01
Cholesterol173.21(46.327)184.22(47.852)<0.01
Triglycerides127.87(66.191)145.96(108.627)0.03
Thrombocytes255431(116888)239133(110479)0.03
Haemoglobin12.78(2.309)13.7851(1.87791)<0.01
Glycemia122.48(41.718)129.63(49.251)0.03
ESR30.00(28.901)18.70(18.255)<0.01
DOI: https://doi.org/10.2478/jccm-2021-0002 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 54 - 61
Submitted on: Sep 21, 2020
Accepted on: Jan 5, 2021
Published on: Jan 29, 2021
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2021 Anca Motataianu, Smaranda Maier, Sebastian Andone, Laura Barcutean, Georgiana Serban, Zoltan Bajko, Adrian Balasa, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.