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Bilateral Ocular Exophthalmia – A Case of Atypical Acute Myeloblastic Leukemia in a Child Cover

Bilateral Ocular Exophthalmia – A Case of Atypical Acute Myeloblastic Leukemia in a Child

The Journal of Critical Care Medicine
Volume 6 (2020): Issue 4 (October 2020)
By: Réka Toth,  Alina Grama,  Cristina Maki and  Mihaela Ioana Chinceșan  
Open Access
|Nov 2020

Figures & Tables

Fig. 1

Proptosis of the right eye in the first 24 hours after admission to the Paediatric Clinic
Proptosis of the right eye in the first 24 hours after admission to the Paediatric Clinic

Fig. 2

The non-contrast-enhanced cranial/cerebral CT of the head with coronal sections at the level of the orbits, shows two well-defined, soft-tissue density lesions in the supero-lateral aspect of the extraconal regions bilaterally, more pronounced on the right side, where downward displacement of the ocular globe is visible
The non-contrast-enhanced cranial/cerebral CT of the head with coronal sections at the level of the orbits, shows two well-defined, soft-tissue density lesions in the supero-lateral aspect of the extraconal regions bilaterally, more pronounced on the right side, where downward displacement of the ocular globe is visible

Fig. 3

Contrast-enhanced cranial CT axial view of the head and orbit, following intravenous iodinated contrast media administration. The lesions show mild, homogenous enhancement.
Contrast-enhanced cranial CT axial view of the head and orbit, following intravenous iodinated contrast media administration. The lesions show mild, homogenous enhancement.

Routine tests results performed on Day 1 post-admission to Paediatrics Clinic

CRPFgESRLDHASTALTCreatinineUrea
41.66 mg/l497 mg/dl93 mm/h601 U/l21 U/l8 U/l0,69 mg/dl26,1 mg/dl

Bone marrow immunophenotyping

CD34HLA-DRCD13CD33CD15CD117CD19CD3CD7CD10CD22CD11CD14CD64
80%80%78%75%70%60%62%negativenegativenegativenegativenegativenegativenegative

Supportive care of the induction phase_

Drug nameStrengthDosageRoute of administrationDates of administration
human immune globulin2,5g/25ml1 fl/dayintravenouslyDay 13
(CSL Behring GmbH, Marburg, Germany)
red blood cell10ml/kgintravenouslyDay 9,21
pooled platelets1unit/10kgintravenouslyDay 7-16, 21-25
trimethoprim-sulfamethoxazole(40mg/200mg)/5ml2x10ml/dayorallyDay 24-26
(E.I.P.I.Co., Tenth of Ramadan City, Egypt)
fluconazole2mg/ml100 mg onceintravenouslyDay 17-27
(Fareva Amboise, Pocé-Sur-Cisse, France)daily
granisetron1mg/ml1mg twice aIntravenouslyDay 4-11
(Fresenius Kabi Austria GmbH, Graz, Austria)day
DOI: https://doi.org/10.2478/jccm-2020-0031 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
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Language: English
Page range: 243 - 248
Submitted on: May 15, 2020
|
Accepted on: Aug 29, 2020
|
Published on: Nov 7, 2020
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
bilateral ocular exophthalmos,
atypical onset,
acute myeloblastic leukaemia,
myeloid sarcoma
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Internal medicine, other,
Surgery,
Surgery, other,
Anaesthesiology,
Emergency medicine and intensive-care medicine

© 2020 Réka Toth, Alina Grama, Cristina Maki, Mihaela Ioana Chinceșan, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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