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The Diagnostic and Prognostic Role of Vascular Endothelial Growth Factor C in Sepsis and Septic Shock Cover

The Diagnostic and Prognostic Role of Vascular Endothelial Growth Factor C in Sepsis and Septic Shock

The Journal of Critical Care Medicine
Volume 6 (2020): Issue 3 (July 2020)
By: ,  ,  ,  ,  ,  ,  ,  ,  ,  ,   and    
Open Access
|Aug 2020
Figures & tables

Figures & Tables

Table 1

Demographic data and length of stay in ICU for Group A (sepsis) and Group B (septic shock)

VariablesGroup AGroup BP-value
Age(years)65(68)69(56)0.17**
median (range)
Gender, male (n, %)35(60%)22(44%)
Gender, female (n, %)23(40%)27(56%)0.12*

** Mann-Whitney test

* Chi-square test

Table 2

qSOFA, SOFA, MODS, APACHE II scores in Groups A and B

VariablesGroup AGroup BP value
qSOFA score (median)22>0.999
SOFA (median, score range)5 (0-16)8 (0-18)<0.0001
MODS (median, score range)4.9 (0-10)9.2 (2-18)<0.0001
APACHE (median, II range) score17 (6-39)23 (5-39)<0.0001

[i] * Mann-Whitney test; ** Fisher’s exact test; QSOFA Quick Sequential Organ Failure Assessment; SOFA Sequential Organ Failure Assessment; MODS Multiple Organ Dysfunction Syndrome; APACHE II Acute Physiology and Chronic Health Evaluation.

Fig. 1

Mean values of plasma VEGF-C levels in Group A (sepsis), Group B (septic shock) and Group C (healthy controls)

Fig. 2

ROC curve for plasma VEGF-C levels for septic shock (AUC = 0.709, p = 0.001)

DOI: https://doi.org/10.2478/jccm-2020-0020 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
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Language: English
Page range: 152 - 158
Submitted on: Aug 20, 2019
Accepted on: Apr 23, 2020
Published on: Aug 11, 2020
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
vascular endothelial growth factor C,
sepsis,
septic shock,
lymphangiogenesis
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Internal medicine, other,
Surgery,
Surgery, other,
Anaesthesiology,
Emergency medicine and intensive-care medicine

© 2020 Emoke Almasy, Janos Szederjesi, Bianca Liana Grigorescu, Iudita Badea, Marius Petrisor, Cristina Manasturean, Valentina Negrea, Agota-Evelyn Timar, Oana Coman, Leonard Azamfirei, Ario Santini, Sanda Maria Copotoiu, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 6 (2020): Issue 3 (July 2020)
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