Have a personal or library account? Click to login
Refractory Lactic Acidosis and an Approach to Its Management - A Case Report Cover

Refractory Lactic Acidosis and an Approach to Its Management - A Case Report

By: Yingke He,  John Ong and  Sharon Ong  
Open Access
|May 2019

References

  1. Jung B, Rimmele T, Le Goff C, et al. Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. a prospective, multiple-center study. Crit Care. 2011;15(5):R238.
  2. Iberti TJ, Leibowitz AB, Papadakos PJ, Fischer EP. Low sensitivity of the anion gap as a screen to detect hyperlactatemia in critically ill patients. Crit Care Med. 1990;18:275-7.
  3. Fall PJ, Szerlip HM. Lactic acidosis: from sour milk to septic shock. J Intensive Care Med. 2005;20:255–71.
  4. Kraut JA, Madias NE. Lactic Acidosis. New Eng J Med. 2014;371: 2309–19.
  5. Ferraris AM, Giuntini P, Gaetani GF. Serum lactic dehydrogenase as a prognostic tool for non-Hodgkin lymphomas. Blood. 1979;54:928–32.
  6. Wilkinson JH. Lactate Dehydrogenase Isoenzymes. In Isoenzymes. New York: Springer. 1970, pp.134-203.
  7. Warburg O. On the origin of cancer cells. Science. 1956;123:309–14.
  8. Koppenol WH, Bounds PL, Dang CV. Otto Warburg’s contributions to current concepts of cancer metabolism. Nat Rev Cancer. 2011;11:325–37.
  9. Ahuja P, Zhao P, Angelis E, et al. Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. J Clin Invest. 2010;120:1494–505.
  10. Dang CV. c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol. 1999;19:1–11.
  11. Yun J, Rago C, Cheong I, et al. Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Science. 2009;325:1555–9.
  12. Ramanathan A, Wang C, Schreiber SL. Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci USA. 2005;102:5992–7.
  13. Elstrom RL, Bauer DE, Buzzai M, et al. Akt stimulates aerobic glycolysis in cancer cells. Cancer Re.s 2004;64:3892–9.
  14. Robey RB, Hay N. Is Akt the ‘Warburg kinase’?-Akt-energy metabolism interactions and oncogenesis. Semin Cancer Biol. 2009;19:25–31.
  15. Deprez J, Vertommen D, Alessi DR, Hue L, Rider MH. Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades. J Biol Chem. 1997;272:17269–75.
  16. Matoba S, Kang JG, Patino WD, et al. p53 regulates mitochondrial respiration. Science. 2006;312:1650–3.
  17. Vousden KH, Ryan KM. p53 and metabolism. Nat Rev Cancer. 2009;9:691–700.
  18. Zhang C, Liu J, Liang Y, et al. Tumour-associated mutant p53 drives the Warburg effect. Nat. Commun. 2013;4,2935.
  19. Kruse O, Grunnet N, Barfod C. Blood lactate as a predictor for in-hospital mortality in patients admitted acutely to hospital: a systematic review. Scand J Trauma Resusc Emerg Med. 2001;19:74.
  20. Bloom BM, Grundlingh J, Bestwick JP, Harris T. The role of venous blood gas in the emergency department: a systematic review and meta-analysis. Eur J Emerg Med. 2014;21:81–8.
  21. Réminiac F, Saint-Etienne C, Runge I, et al. Are central venous lactate and arterial lactate interchangeable? A human retrospective study. Anesth Analg. 2012;115:605–10.
  22. Vitin AA, Azamfirei L, Tomescu D, Lang JD. Perioperative Management of Lactic Acidosis in End-Stage Liver Disease Patient. J Crit Care Med (Targu Mures). 2017;3:55–62.
  23. del Portal DA, Shofer F, Mikkelsen ME, et al. Emergency department lactate is associated with mortality in older adults admitted with and without infections. Acad Emerg Med. 2010;17:260–8.
  24. Juneja D, Singh O, Dang R. Admission hyperlactatemia: causes, incidence, and impact on outcome of patients admitted in a general medical intensive care unit. J Crit Care. 2011;26:316–20.
DOI: https://doi.org/10.2478/jccm-2019-0010 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 60 - 65
Submitted on: Mar 12, 2019
|
Accepted on: Apr 24, 2019
|
Published on: May 13, 2019
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2019 Yingke He, John Ong, Sharon Ong, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.