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The pathway of lead through the mother’s body to the child Cover

The pathway of lead through the mother’s body to the child

By: Vanda Rísová  
Open Access
|Feb 2020

Abstract

Placenta, the organ on which great attention is concentrated during pregnancy, represents an ineffective barrier to the transfer of hazardous heavy metals, mainly lead, into the foetus. The presence of lead in the placenta is an environmental hazard for a person’s future. Due to hormonal changes, lead is released during pregnancy into the bloodstream of the mother from deposits in the bones and in the teeth, where it has accumulated for years as a result of a contaminated environment. Since lead is a neurotoxic metal, exposure to lead during prenatal and postnatal development can cause serious neurocognitive damage and hence the development of an Attention Deficit Hyperactivity Disorder (ADHD) in a developing human. Our work provides an overall picture of the “toxic pathway“ of lead through the mother’s body, the risks arising from its transplacental transfer and its accumulation in the developing foetus as well as effective prevention to protect all newborns.

DOI: https://doi.org/10.2478/intox-2019-0001 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853
Language: English
Page range: 1 - 6
Submitted on: Feb 2, 2019
Accepted on: Jun 4, 2019
Published on: Feb 20, 2020
Published by: Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 Vanda Rísová, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.