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Toxicity, mechanism and health effects of some heavy metals Cover

Toxicity, mechanism and health effects of some heavy metals

Open Access
|Nov 2014

Abstract

Heavy metal toxicity has proven to be a major threat and there are several health risks associated with it. The toxic effects of these metals, even though they do not have any biological role, remain present in some or the other form harmful for the human body and its proper functioning. They sometimes act as a pseudo element of the body while at certain times they may even interfere with metabolic processes. Few metals, such as aluminium, can be removed through elimination activities, while some metals get accumulated in the body and food chain, exhibiting a chronic nature. Various public health measures have been undertaken to control, prevent and treat metal toxicity occurring at various levels, such as occupational exposure, accidents and environmental factors. Metal toxicity depends upon the absorbed dose, the route of exposure and duration of exposure, i.e. acute or chronic. This can lead to various disorders and can also result in excessive damage due to oxidative stress induced by free radical formation. This review gives details about some heavy metals and their toxicity mechanisms, along with their health effects

DOI: https://doi.org/10.2478/intox-2014-0009 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853
Language: English
Page range: 60 - 72
Submitted on: Apr 2, 2014
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Accepted on: Jun 26, 2014
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Published on: Nov 15, 2014
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2014 Monisha Jaishankar, Tenzin Tseten, Naresh Anbalagan, Blessy B. Mathew, Krishnamurthy N. Beeregowda, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.