Have a personal or library account? Click to login
Can Tirzepatide Revolutionize Gastric Cancer Prevention? A Comprehensive Analysis Cover

Can Tirzepatide Revolutionize Gastric Cancer Prevention? A Comprehensive Analysis

Open Access
|Jul 2025

References

  1. Baggio, L. L., & Drucker, D. J. (2021). Glucagon-like peptide-1 receptor agonists: Mechanisms of action and therapeutic applications. Cell Metabolism, 33(4), 740-755.
  2. Cummings, D. E., & Rubino, F. (2018). Metabolic surgery for the treatment of type 2 diabetes in obese individuals. Diabetologia, 61(2), 257-264.
  3. Groll, D. L., & Wexler, D. J. (2023). Tirzepatide: A novel dual agonist for the treatment of type 2 diabetes and obesity. Lancet Diabetes&Endocrinology, 11(1), 55-67.
  4. Rabe, M. D., & Lehrke, M. (2020). Adipokines and insulin resistance in obesity-related inflammation and cancer. Trends in Endocrinology & Metabolism, 31(5), 317-329.
  5. Van Cutsem, E., et al. (2021). Gastric cancer: ESMO clinical practice guidelines. Annals of Oncology, 32(6), 707-720.
  6. Sajjad, A., & Saeed, F. (2023). Genetic predisposition and response to GLP-1 receptor agonists: Implications for personalized treatment. Diabetes, Obesity, and Metabolism, 25(5), 1164-1174.
  7. Patel, S. H., & Finkelstein, D. (2020). Tirzepatide and its effect on metabolic and oncologic outcomes: A promising future. Cancer Prevention Research, 13(4), 332-340.
  8. Li, S. Y., & Lee, M. (2022). The tumor microenvironment and therapeutic interventions: Implications for gastric cancer treatment. Frontiers in Oncology, 12, 712109.
  9. Fuchs, C. S., & Liptay, M. (2019). Metabolic regulation and gastric cancer: Potential interventions for cancer prevention. The Lancet Oncology, 20(8), 1025-1035.
  10. Schoon, E. K., & LeDuc, C. M. (2021). Obesity, insulin resistance, and their link to cancer: Mechanisms and clinical implications. Nature Reviews Endocrinology, 17(3), 133-143.
  11. Boucher, J. L., & Lee, D. (2018). GLP-1 receptor agonists and cancer risk: A review of the current literature. Cancer Medicine, 7(6), 2704-2712.
  12. Blake, M. A., & Blevins, T. C. (2020). Tirzepatide: A novel dual GLP-1/GIP receptor agonist for the treatment of obesity and type 2 diabetes. Journal of Clinical Endocrinology&Metabolism, 105(10), e3777-e3787.
DOI: https://doi.org/10.2478/inmed-2025-0318 | Journal eISSN: 1220-5818 | Journal ISSN: 1220-5818
Language: English
Page range: 47 - 58
Published on: Jul 23, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Alexandra Orășeanu, Amina Venter, Sabina Florina Șolea, Ciprian Mihai Brisc, Mihaela Cristina Brisc, Ciprian Brisc, Horia Popa, published by Romanian Society of Internal Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.