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Thrombophilia: An Amalgam of Never Ending Clinical Manifestations Cover

Abstract

Thrombophilia is a blood coagulation disorder, in which blood has an increased tendency to clot, with both arterial and venous localization, being responsible for multiple manifestations: secondary arterial hypertension, stroke, acute pancreatitis or intracardiac masses. We are presenting the case of a 21-year-old male patient, hypertensive, known with thrombophilia, who was sent for the echocardiographic evaluation of an intracardiac mass attached to the posterior leaflet of the mitral valve. The echocardiography and transesophageal echocardiogram showed a hyperechogenic, homogeneous intracardiac mass, attached to the posterior leaflet of the mitral valve, the clinical context and the echocardiographic appearance being suggestive for a thrombus. Given the context of thrombophilia and the hypertension’s characteristics, we considered a secondary form of hypertension, the incriminated mechanism being represented by microthrombosis in the renal arterial circulation. There were two complications in the evolution of the patient: stroke and the recurrent acute pancreatitis, both being explained in the context of thrombophilia. The discharge echocardiography showed a favorable evolution, with a complete resolution of the thrombus under the anticoagulant treatment.

DOI: https://doi.org/10.2478/inmed-2022-0218 | Journal eISSN: 1220-5818 | Journal ISSN: 1220-5818
Language: English
Page range: 41 - 48
Published on: Oct 15, 2022
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2022 Ștefania Teodora Duca, Florin Mitu, Andreea Timofte, Adriana Chetran, Monica Ureche, Daniela Crișu, Ovidiu Mitu, Alexandru Dan Costache, Irina Iuliana Costache, published by Romanian Society of Internal Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.