Neutrophil to Lymphocyte Ratio and Thrombocyte to Lymphocyte Ratio, New Biochemical Parameters in Acute Pancreatitis

Background. Acute pancreatitis represents an inflammatory disease with different grades of severity, ranging from mild to severe presentation. In current practice there are a lot of biomarkers used in diagnosis and prognosis of pancreatitis.

The aim of this study was to evaluate de differences between a group with acute pancreatitis and a group of healthy people regarding the neutrophil to lymphocyte ratio (NLR), thrombocyte to lymphocyte ratio (TLR), as these two could help in the evaluation of prognosis and severity of acute pancreatitis.

Method. The study had two groups: group A, included 100 patients with acute pancreatitis and group B - 30 healthy people.

Results. In the group A there were 65% male and 35 % female with a mean age of 58.07±15.10 years, in the group B there were 50% male and 50% female with a mean age of 48.06±15.47 years. The majority of the people included in both groups were from the urban provenience. We obtained an important difference between group A and group B regarding the neutrophil to lymphocyte ratio and thrombocyte to lymphocyte ratio with an important statistical significance (p<0.001).

Conclusion. Neutrophil to lymphocyte ratio and thrombocyte to lymphocyte ratio could be promising biochemical parameters in diagnosis and prognosis of acute pancreatitis.