Have a personal or library account? Click to login
The second reported case of a hemolytic transfusion reaction caused by anti-Sc2: a clinical diagnosis Cover

The second reported case of a hemolytic transfusion reaction caused by anti-Sc2: a clinical diagnosis

Paid access
|Dec 2025

References

  1. Brunker PAR, Flegel WA. An update on the Scianna blood group system. Immunohematology 2019;35:48–50.
  2. Floch A, Lomas-Francis C, Vege S, et al. Two new Scianna variants causing loss of high prevalence antigens: ERMAP model and 3D analysis of the antigens. Transfusion 2023;63:230–8. doi: 10.1111/trf.17182.
  3. Srivastava K, Albasri J, Alsuhaibani OM, et al. SCAR: the high-prevalence antigen 013.008 in the Scianna blood group system. Transfusion 2021;61:246–54. doi: 10.1111/trf.16152.
  4. Anderson C, Hunter J, Zipursky A, Lewis M, Chown B. An antibody defining a new blood group antigen, Bua. Transfusion 1963;3:30–3. doi: 10.1111/j.1537-2995.1963.tb04599.x.
  5. Schmidt RP, Griffitts JJ, Northman FF. A new antibody, anti-Sm, reacting with a high incidence antigen. Transfusion 1962;2:338–40. doi: 10.1111/j.1537-2995.1962.tb00250.x.
  6. Daniels G. Scianna blood group system. In: Human blood groups. John Wiley & Sons, Hoboken, NJ, 2013:371–5. doi: 10.1002/9781118493595.ch13.
  7. DeMarco M, Uhl L, Fields L, Pacini D, Gorlin JB, Kruskall MS. Hemolytic disease of the newborn due to the Scianna antibody, anti-Sc2. Transfusion 1995;35:58–60. doi: 10.1046/j.1537-2995.1995.35195090664.x.
  8. Núñez Ahumada MA, Arancibia Aros CE, Villalobos Pavez CE, et al. A mild case of hemolytic disease of the fetus and newborn due to anti-Sc2. Immunohematology 2021;37:122–5. doi: 10.21307/immunohematology-2021-018.
  9. Lemay AS, Tong TN, Branch DR, et al. The first case of severe acute hemolytic transfusion reaction caused by anti-Sc2. Transfusion 2018;58:2506–12. doi: 10.1111/trf.14867.
  10. Reid ME, Lomas-Francis C, Olsson ML. The blood group antigen factsbook. 3rd ed. Academic Press, San Diego, CA, 2012.
  11. Panch SR, Montemayor-Garcia C, K lein HG. Hemolytic transfusion reactions. N Engl J Med 2019;381:150–62. doi: 10.1056/NEJMra1802338.
  12. Alvarez A, Rives S, Montoto S, Sanz C, Pereira A. Relative sensitivity of direct antiglobulin test, antibody’s elution and flow cytometry in the serologic diagnosis of immune hemolytic transfusion reactions. Haematologica 2000;85:186–8.
  13. Zanetti RC, Vasta LM, Romanelli K, Newton TC. Management of hyperhemolysis in β-thalassemia with multiple immunosuppressives, including complement blockade. J Pediatr Hematol Oncol 2021;43:e1145–7. doi: 10.1097/MPH. 0000000000002059.
  14. Kasinathan G, Sathar J. Post-transfusion hyperhemolysis syndrome in a patient with beta thalassemia major. Clin Case Rep 2021;9:e04226. doi: 10.1002/ccr3.4226.
  15. Jacobs JW, Stephens LD, Allen ES, et al. Epidemiological and clinical features, therapeutic strategies and outcomes in patients with hyperhaemolysis: a systematic review. Br J Haematol 2023;201:1025–32. doi: 10.1111/bjh.18825.
DOI: https://doi.org/10.2478/immunohematology-2025-019 | Journal eISSN: 1930-3955 | Journal ISSN: 0894-203X
Language: English
Page range: 132 - 135
Published on: Dec 31, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Hang Mieu Ha, Wesley Rubenstein, Maryam Asif, published by American National Red Cross
This work is licensed under the Creative Commons License.