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A PRISMA-based Comparative Analysis of Machine Learning Techniques in Diagnosing Electrocardiogram, Diabetes, Chronic Kidney Disease, and Breast Cancer Cover

A PRISMA-based Comparative Analysis of Machine Learning Techniques in Diagnosing Electrocardiogram, Diabetes, Chronic Kidney Disease, and Breast Cancer

Open Access
|Apr 2026

Figures & Tables

Figure 1:

Classification of the ECG arrhythmia system.

Figure 2:

Different forms of diabetes.

Figure 3:

Factors of CKD. CKD, chronic kidney disease.

Figure 4:

Application of ML in the healthcare industry. ML, machine learning.

Figure 5:

Review’s structural flow.

Figure 6:

Methodology framework from data analysis. CKD, chronic kidney disease.

Figure 7:

Keyword analysis. CKD, chronic kidney disease.

Figure 8:

Year-wise annual scientific production of diseases. CKD, chronic kidney disease.

Figure 9:

Average citation per year. CKD, chronic kidney disease.

Figure 10:

Author productivity through Lotka’s law. CKD, chronic kidney disease.

Figure 11:

Core sources by Bradford’s law. CKD, chronic kidney disease.

Figure 12:

Country scientific production. CKD, chronic kidney disease.

Figure 13:

Most cited countries. CKD, chronic kidney disease.

Figure 14:

ECG trend topics.

Figure 15:

Diabetes trend topics.

Figure 16:

CKD trend topics. CKD, chronic kidney disease.

Figure 17:

Breast cancer trend topics.

Figure 18:

ECG three fields plot.

Figure 19:

Diabetes three fields plot.

Figure 20:

CKD three fields plot. CKD, chronic kidney disease.

Figure 21:

Breast cancer three-field plot.

Research questions_

Research question No.Research questionObjective
1.How can the integration of AI-driven methodologies in breast cancer research improve early detection and personalized treatment plans?
  • Review recent advancements in AI methodologies as reported in journals like AI in Medicine.

  • Identify key AI techniques that have been successfully applied to breast cancer detection and treatment personalization.

2.How does the volume of research publications in ECG, CKD, diabetes, and breast cancer correlate with healthcare challenges and research priorities in different countries?Interpret how these research patterns might indicate the healthcare challenges faced by these countries.
3.How does author productivity vary among ECG, diabetes, CKD, and breast cancer research fields according to Lotka’s law?Determine which field has the highest and lowest percentage of highly productive authors.
4.What insights can Biblioshiny keyword co-occurrence analysis provide for a specific field of research?Keyword co-occurrence analysis identifies the most frequent terms in a field, revealing key research themes, emerging trends, and areas of academic focus or future opportunities.

Inclusion and exclusion criteria_

Inclusion criteriaExclusion criteria
  • Studies focusing on applying ML algorithms in medical diagnosis and prognosis.

  • Research articles discussing the use of ML in disease prediction, including but not limited to diabetes, CKD, breast cancer, and heartbeat categorization on an ECG.

  • Papers that present ML classifiers’ performance metrics, such as sensitivity, specificity, accuracy, and AUC.

  • Investigations into the integration of ML techniques for disease detection and management, emphasizing efficiency and accuracy.

  • Studies published within the last 4 years to ensure relevance and currency

  • Articles do not focus on ML applications in healthcare or medical diagnosis.

  • Studies unrelated to disease prediction or classification using ML methodologies.

  • Papers lacking performance metrics or evaluations of ML classifiers’ effectiveness.

  • Research published before 2020 or after 2023 to maintain the focus on recent advancements in the field.

  • Investigations not aligned with the specific diseases mentioned, such as those addressing unrelated medical conditions or applications.

Literature review from 2020 to 2024_

ReferenceYearAlgorithm implementedContribution
[42]202412 different classifiers that belong to six learning strategies were evaluated using two datasets.Diagnosing diabetes
[43]2024Ten ML classifiers were usedPrediction of diabetes disease through a mobile app
[35]2024Used sensor technologyWork on gestational diabetes
[7]2023Gradient boosting tree, RF, KNN, and SVMThe authors study an automatic arrhythmia classification method for the healthcare system, the MHO algorithm, and the ML classifier.
[6]2023Convolutional neural networkThe CNN algorithm is used for feature extraction on the ECG image dataset
[44]2023NB, LR, SVM, KNN, DT, AdaBoost, XGboostCompared the performance level by using AUC
[40]2022SVM, LR, DT, XGBOOST, RF, AdaBoostADAboost provides 100% sensitivity for the detection of CKD
[45]2022SVM, RF, Gradient boosting, Ada boostPredicting breast cancer based on different medical symptoms
[41]2021RF, XGBOOST, neural networkEvaluated the risk of CKD
[10]20218 ML classifiers were usedPerformance analysis of CKD
[46]2021SVM, RF, LR, DT, KNNBreast cancer prediction and diagnosis
[47]2020Six supervised ML algorithmsPrediction of breast cancer using various ML algorithms
[9]2020K-nearest neighbor, LR, RF, SVM, and decision treeDiabetes prediction
[38]2020Eleven ML classifiers were usedPrediction of CKD
[39]2020Seven ML techniques are utilizedClassifying the kidney patient dataset as CKD or NOTCKD
[30]2020SVMAn SVM classifier is proposed to classify the heartbeat. The result of SVM was compared with other classifiers
[29]2020SVM, KNN, ANNConstruct a biometric recognition system

Summary of the ML classification and clustering algorithms in terms of accuracy_

Supervised ML
Classification algorithmsReferencesYearTaskAccuracy (%)
Support vector regression[18]2022Predicting and illustrating the COVID-19 pandemic94
Decision trees[19]2022Prediction of diabetes96
Naïve Bayes[20]2020Skin disease detection94.3
Naïve Bayes[21]2020Heart disease detection88.16
Ensemble techniques[22]2020Predict the normal weekly cost that patients will spend on specific medicines98
Decision trees[23]2020Heart disease prediction88
SVM[24]2019Speech recognition, facial recognition91.3
Language: English
Submitted on: Dec 9, 2024
Published on: Apr 10, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2026 Baljit Kaur, Renu Popli, Hiran Mani Bala, published by Macquarie University, Australia
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.