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A pilot study on the potency of injectable vs. oral moxidectin formulation to suppress strongyle egg excretion in horses at twice lower dose Cover

A pilot study on the potency of injectable vs. oral moxidectin formulation to suppress strongyle egg excretion in horses at twice lower dose

Helminthologia
Volume 62 (2025): Issue 2 (June 2025)
By:
Open Access
|Sep 2025

Figures & Tables

Fig. 1.

The mean number of strongylid eggs/g of feces (EPG) in Group OT (N=5; blue solid bars) and Group IT (N=4; red pattern bars) with standard deviation (SD; vertical error bars) over 42 days post treatment (d.p.t.) presented on logarithmically transformed scale. The missing values on days 28 and 35 represent 0 EPG counts. *Signifi cant reduction in Group OT (P<0.001) and Group IT (P<0.01) as compared to respective groups on day 0.
The mean number of strongylid eggs/g of feces (EPG) in Group OT (N=5; blue solid bars) and Group IT (N=4; red pattern bars) with standard deviation (SD; vertical error bars) over 42 days post treatment (d.p.t.) presented on logarithmically transformed scale. The missing values on days 28 and 35 represent 0 EPG counts. *Signifi cant reduction in Group OT (P<0.001) and Group IT (P<0.01) as compared to respective groups on day 0.

Fig. 2.

The mean efficacy of moxidectin oral gel in Group OT (N=5; blue line, bold triangles) and injectable moxidectin in Group IT (N=4; red line, bold rectangles) in reducing strongylid egg excretion and 95 % confidence intervals (vertical error bars) over 42 days post treatment (d.p.t.) with the dotted (89.43 %; Group OT) and dashed (89.32 %; Group IT) lines representing threshold set 10 % below the FECT determined at 17 days post-treatment. Significantly higher (*P<0.05; **0.001) as compared to other group on the same time point.
The mean efficacy of moxidectin oral gel in Group OT (N=5; blue line, bold triangles) and injectable moxidectin in Group IT (N=4; red line, bold rectangles) in reducing strongylid egg excretion and 95 % confidence intervals (vertical error bars) over 42 days post treatment (d.p.t.) with the dotted (89.43 %; Group OT) and dashed (89.32 %; Group IT) lines representing threshold set 10 % below the FECT determined at 17 days post-treatment. Significantly higher (*P<0.05; **0.001) as compared to other group on the same time point.
DOI: https://doi.org/10.2478/helm-2025-0018 | Journal eISSN: 1336-9083 | Journal ISSN: 0440-6605
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Language: English
Page range: 87 - 94
Submitted on: Jun 3, 2025
Accepted on: Jul 11, 2025
Published on: Sep 30, 2025
Published by: Slovak Academy of Sciences
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
Keywords:
Horse,
Moxidectin,
Effi cacy,
Resistance,
Egg reappearance period
Related subjects:
Life sciences,
Zoology,
Ecology,
Life sciences, other,
Medicine,
Clinical medicine,
Microbiology, virology and infection epidemiology

© 2025 M. Šarkūnas, A. Schwahn, K. Suleimanova, published by Slovak Academy of Sciences
This work is licensed under the Creative Commons Attribution 4.0 License.

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