References
- Arena C, De Micco V, Macaeva E, Quintens R (2014) Space radiation effects on plant and mammalian cells. Acta Astronautica104: 419–431
- Ave M, Boyle P, Brannon E, Gahbauer F, Hermann G, Höppner C, Hörandel J, Ichimura M, Müller D, Obermeier A (2011) The TRACER instrument: A balloon-borne cosmic-ray detector. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment654: 140–156
- Badhwar GD, O’Neill PM (1992) An improved model of galactic cosmic-radiation for space exploration missions. Nuclear Tracks and Radiation Measurements20: 403–410
- Benton E (2012) Space radiation passive dosimetry. The Health Risks of Extraterrestrial Environments
https://three.jsc.nasa.gov/articles/BentonPassive-Dosimetry.pdf - Benton ER, Benton EV (2001) Space radiation dosimetry in low-Earth orbit and beyond. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms184: 255–294
- Berardini TZ, Reiser L, Li D, Mezheritsky Y, Muller R, Strait E, Huala E (2015) The Arabidopsis information resource: Making and mining the “gold standard” annotated reference plant genome. Genesis53: 474–485
- Cartwright BG, Shirk EK, Price PB (1978) A nuclear-track-recording polymer of unique sensitivity and resolution. Nuclear Instruments and Methods153: 457–460
- Chin C-S, Peluso P, Sedlazeck FJ, Nattestad M, Concepcion GT, Clum A, Dunn C, O’Malley R, Figueroa-Balderas R, Morales-Cruz A, Cramer GR, Delledonne M, Luo C, Ecker JR, Cantu D, Rank DR, Schatz MC (2016) Phased diploid genome assembly with single-molecule real-time sequencing. Nature Methods13: 1050
- De Micco V, Arena C, Pignalosa D, Durante M (2011) Effects of sparsely and densely ionizing radiation on plants. Radiation and Environmental Biophysics50: 1–19
- Durante M (2014) Space radiation protection: Destination Mars. Life Sciences in Space Research1: 2–9
- Feng S, Cokus SJ, Schubert V, Zhai J, Pellegrini M, Jacobsen SE (2014) Genome-wide Hi-C analyses in wild-type and mutants reveal high-resolution chromatin interactions in Arabidopsis. Molecular Cell55: 694–707
- Gangappa SN, Botto JF (2016) The multifaceted roles of HY5 in plant growth and development. Molecular Plant9: 1353–1365
- Griffith PM, Raley C, Sun D, Zhao Y, Sun Z, Mehta M, Tran B, Wu X (2018) PacBio library preparation using blunt-end adapter ligation produces significant artefactual fusion DNA sequences. bioRxiv
- Hada M, Zhang Y, Feiveson A, Cucinotta FA, Wu H (2011) Association of inter- and intrachromosomal exchanges with the distribution of low- and high-LET radiation-induced breaks in chromosomes. Radiation Research176: 25–37
- Huefner ND, Yoshiyama K, Friesner JD, Conklin PA, Britt AB (2014) Genomic stability in response to high versus low linear energy transfer radiation in Arabidopsis thaliana. Frontiers in Plant Science5: 206
- Kavanagh JN, Redmond KM, Schettino G, Prise KM (2013) DNA double strand break repair: a radiation perspective. Antioxidants & Redox Signaling18: 2458–2472
- Kazama Y, Saito H, Yamamoto YY, Hayashi Y, Ichida H, Ryuto H, Fukunishi N, Abe T (2008) LET-dependent effects of heavy-ion beam irradiation in Arabidopsis thaliana. Plant Biotechnology25: 113–117
- Kennedy AR (2014) Biological effects of space radiation and development of effective countermeasures. Life Science in Space Research1: 10–43
- Kiffer F, Carr H, Groves T, Anderson JE, Alexander T, Wang J, Seawright JW, Sridharan V, Carter G, Boerma M, Allen AR (2017) Effects of 1H + 16O charged particle irradiation on short-term memory and hippocampal physiology in a murine model. Radiation Research189: 53–63
- Kim K, Amare Y, Anderson T, Angelaszek D AN, Cheriyan K, Choi GH, Copley M, Coutu S, Derome L, Eraud L, Hagenau L, Han JH, Huh HG, Im S, Jeon JA, Jeong S, Kim MH, Lee HY, Lee J, Lee MH, Liang J, Link JT, Lu L, Lutz L, Mernik T, Mitchell JW, Mognet SI, Morton S, Nester M, Nutter S, Ofoha O, Park IH, Picot-Clémente N, Quinn R, Seo ES, Smith JR, Walpole P, Weinmann RP, Wu J, Yoon YS (2017) Boron And Carbon Cosmic Rays in the Upper Stratosphere (BACCUS). In Proceedings of Science: 35th International Cosmic Ray Conference.
- Kranz AR (1986) Genetic and physiological damage induced by cosmic radiation on dry plant seeds during space flight. Advances in Space Research6: 135–138
- Krzywinski M, Schein J, Birol I, Connors J, Gascoyne R, Horsman D, Jones SJ, Marra MA (2009) Circos: an information aesthetic for comparative genomics. Genome Research19: 1639–1645
- Lake JA, Field KJ, Davey MP, Beerling DJ, Lomax BH (2009) Metabolomic and physiological responses reveal multi-phasic acclimation of Arabidopsis thaliana to chronic UV radiation. Plant, Cell and Environment32: 1377–1389
- Lavelle C, Foray N (2014) Chromatin structure and radiation-induced DNA damage: From structural biology to radiobiology. The International Journal of Biochemistry & Cell Biology49: 84–97
- LeFrois CE, Zhou M, Amador DM, Sng N, Paul A-L, Ferl RJ (2016) Enabling the spaceflight methylome: DNA isolated from plant tissues preserved in RNAlater™ is suitable for bisulfite PCR assay of genome methylation. Gravitational and Space Research4: 28–37
- Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N, Marth G, Abecasis G, Durbin R, Genome Project Data Processing Subgroup (2009) The sequence alignment/map format and SAMtools. Bioinformatics25: 2078–2079
- Liang Z, Shen L, Cui X, Bao S, Geng Y, Yu G, Liang F, Xie S, Lu T, Gu X, Yu H (2018) DNA N6-adenine methylation in Arabidopsis thaliana. Developmental Cell45: 406–416
- Miller J, Zeitlin C (2016) Twenty years of space radiation physics at the BNL AGS and NASA Space Radiation Laboratory. Life Science in Space Research9: 12–18
- Moreno-Villanueva M, Wong M, Lu T, Zhang Y, Wu H (2017) Interplay of space radiation and microgravity in DNA damage and DNA damage response. npj Microgravity3: 14
- NASA (2018) Human Research Program Integrated Research Plan. NASA/HRP-47065-RevJ
https://humanresearchroadmap.nasa.gov/ - NCRP (1995) Radiation Exposure and High Altitude Flight, Commentary #12. Bethesda, MD: US National Council for Radiation Protection and Measurements
- NOAA (2016) Report and Forecast of Solar and Geophysical Activity, National Oceanic & Atmospheric Administration
- Robinson JT, Thorvaldsdottir H, Wenger AM, Zehir A, Mesirov JP (2017) Variant review with the integrative genomics viewer. Cancer Research77: e31–e34
- Roldán-Arjona T, Ariza RR (2009) Repair and tolerance of oxidative DNA damage in plants. Mutation Research/Reviews in Mutation Research681: 169–179
- Sedlazeck FJ, Rescheneder P, Smolka M, Fang H, Nattestad M, von Haeseler A, Schatz MC (2018) Accurate detection of complex structural variations using single-molecule sequencing. Nature Methods15: 461–468
- Smith DJ, Sowa MB (2017) Ballooning for biologists: mission essentials for flying life science experiments to near space on NASA large scientific balloons. Gravitational and Space Research5: 52–73
- Suman S, Kumar S, Moon B-H, Fornace AJ, Datta K (2017) Low and high dose rate heavy ion radiation-induced intestinal and colonic tumorigenesis in APC1638N/+ mice. Life Sciences in Space Research13: 45–50
- Tepfer D, Leach S (2017) Survival and DNA damage in plant seeds exposed for 558 and 682 days outside the International Space Sation. Astrobiology17: 205–215
- Tepfer D, Zalar A, Leach S (2012) Survival of plant seeds, their UV screens, and nptII DNA for 18 months outside the International Space Station. Astrobiology12: 517–528
- Walker KA, Jennings CD, Pulliam J, Ogburn C, Martin GM, Urano M, Turker MS (1997) A cell line selected for resistance to ionizing radiation exhibits cross resistance to other genotoxic agents and a mutator phenotype for loss of heterozygosity events. Somatic Cell and Molecular Genetics23: 111–121
- Wang C, Liu C, Roqueiro D, Grimm D, Schwab R, Becker C, Lanz C, Weigel D (2015) Genome-wide analysis of local chromatin packing in Arabidopsis thaliana. Genome Research25: 246–256
- Waterworth WM, Bray CM, West CE (2015) The importance of safeguarding genome integrity in germination and seed longevity. Journal of Experimental Botany66: 3549–3558
- Waterworth WM, Footitt S, Bray CM, Finch-Savage WE, West CE (2016) DNA damage checkpoint kinase ATM regulates germination and maintains genome stability in seeds. Proceedings of the National Academy of Sciences USA113: 9647–9652
- Zhang Y, Rohde LH, Emami K, Hammond D, Casey R, Mehta SK, Jeevarajan AS, Pierson DL, Wu H (2008) Suppressed expression of non-DSB repair genes inhibits gamma-radiation-induced cytogenetic repair and cell cycle arrest. DNA Repair7: 1835–1845