References
- Aceto J, Nourizadeh-Lillabadi R, Bradamante S, Maier JA, Alestrom P, van Loon JJ, Muller M (2016) Effects of microgravity simulation on zebrafish transcriptomes and bone physiology exposure starting at 5 days post fertilization. npj Microgravity2: 16010
- Alwood JS, Ronca AE, Mains RC, Shelhamer MJ, Smith JD, Goodwin TJ (2017) From the bench to exploration medicine: NASA life sciences translational research for human exploration and habitation missions. npj Microgravity3: 5
- Bagley JR, Murach KA, Trappe SW (2012) Microgravity-induced fiber type shift in human skeletal muscle. Gravitational and Space Biology26(1): 34–40
- Blaser RE, Chadwick L, McGinnis GC (2010) Behavioral measures of anxiety in zebrafish (Danio rerio). Behavioral Brain Research208: 56–62
- Blue Origin (2017) New Shepard Payload User's Guide for Research and Education Missions. NSPM-MA0002-C Rev C. Available via request at
https://www.blueorigin.com/ - Champagne DL, Hoefnagels CC, de Kloet RE, Richardson MK (2010) Translating rodent behavioral repertoire to zebrafish (Danio rerio): relevance for stress research. Behavioral Brain Research214: 332–342
- Chan SS, Williamson T (2018) Detection of mitochondrial toxicity using zebrafish. In Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, Y. Will and J.A. Dykens (eds), pp. 323–346. Wiley
- Chatani M, Mantoku A, Takeyama K, Abduweli D, Sugamori Y, Aoki K, Ohya K, Suzuki H, Uchida S, Sakimura T, Kono Y, Tanigaki F, Shirakawa M, Takano Y, Kudo A (2015) Microgravity promotes osteoclast activity in medaka fish reared at the international space station. Scientific Reports5: 14172
- Chatani M, Morimoto H, Takeyama K, Mantoku A, Tanigawa N, Kubota K, Suzuki H, Uchida S, Tanigaki F, Shirakawa M, Gusev O, Sychev V, Takano Y, Itoh T, Kudo A (2016) Acute transcriptional up-regulation scpecific to osteoblasts/osteoclasts in medaka fish immediately after exposure to microgravity. Scientific Reports6: 39545
- DiMauro S (2004) Mitochondrial diseases. Biochimica et Biophysica Acta1658: 80–88
- Facciol A, Tran S, Gerlai R (2017) Re-examining the factors affecting choice in the light-dark preference test in zebrafish. Behavioral Brain Research327: 21–28
- Fitts RH, Riley DR, Widrick JJ (2000) Physiology of a microgravity environment invited review: microgravity and skeletal muscle. Journal of Applied Physiology (1985)89: 823–839
- Fitts RH, Trappe SW, Costill DL, Gallagher PM, Creer AC, Colloton PA, Peters JR, Romatowski JG, Bain JL, Riley DA (2010) Prolonged space flight-induced alterations in the structure and function of human skeletal muscle fibres. Journal of Physiology588: 3567–3592
- Gerlai R, Lahav M, Guo S, Rosenthal A (2000) Drinks like a fish: zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects. Pharmacology Biochemistry and Behavior67: 773–782
- Girdhar K, Gruebele M, Chemla YR (2015) The behavioral space of zebrafish locomotion and its neural network analog. PLOS One10: e0128668
- Gopalakrishnan R, Genc KO, Rice AJ, Lee SM, Evans HJ, Maender CC, Ilaslan H, Cavanagh PR (2010) Muscle volume, strength, endurance, and exercise loads during 6-month missions in space. Aviation, Space, and Environmental Medicine81: 91–102
- Hodkinson DP, Anderton AR, Posselt NB, Fong JK (2017) An overview of space medicine. British Journal of Anaesthesia119 (S1): i143–i153
- Ijiri K (1995) Fish mating experiment in space - what it aimed at and how it was prepared. Biological Sciences in Space9: 3–16
- Ingebretson JJ, Masino MA (2013) Quantification of locomotor activity in larval zebrafish: considerations for the design of high-throughput behavioral studies. Frontiers in Neural Circuits7: 109
- Laizé V, Gavaia PJ, Cancela ML (2014) Fish: a suitable system to model human bone disorders and discovery drugs with osteogenic or osteotoxic activities. Drug Discovery Today: Diseases Models13: 29–37
- LeBlanc A, Lin C, Shackelford L, Sinitsyn V, Evans H, Belichenko O, Schenkman B, Kozlovskaya I, Oganov V, Bakulin A, Hedrick T, Feeback D (2000) Muscle volume, MRI relaxation times (T2), and body composition after spaceflight. Journal of Applied Physiology (1985)89: 2158–64
- Lee J, Freeman LJ (2014) Zebrafish as a model for developmental neurotoxicity assessment: the application of the zebrafish in defining the effects of arsenic, methylmercury, or lead on early neurodevelopment. Toxics 2014 2(3): 464–495
- Liu Y, Carmer R, Zhang G, Venkatraman P, Brown SA, Pang CP, Zhang M, Ma P, Leung YF (2015) Statistical analysis of zebrafish locomotor response. PLOS One10: e0139521
- Maximino C, Marques de Brito T, Dias CA, Gouveia A, Morato S (2010) Scototaxis as anxiety-like behavior in fish. Nature Protocols5: 209–216
- McKeown KA, Downes GB, Hutson LD (2009) Modular laboratory exercises to analyze the development of zebrafish motor behavior. Zebrafish6: 179–185
- Moro-Aguilar R (2014) The new commercial suborbital vehicles: an opportunity for scientific and microgravity research. Microgravity Science and Technology26: 219–227
- NASA Fact Sheets (n.d.): Atrophy. Available at
https://www.nasa.gov/pdf/64249main_ffs_factsheets_hbp_atrophy.pdf__ (Accessed July 8, 2018) - Pletser V, Migeotte PF, Legros JC, Deneyer B, Caron R (2016). The Suborbital Research Association: using suborbital platforms for science and student experiments. Microgravity Science and Technology28(5): 529–544
- Rahn JJ, Bestman JEZ, Josey BJ, Inks ES, Stackley KD, Rogers CE, Chou CJ, Chan SS (2014). Novel vitamin K analogs suppress seizures in zebrafish and mouse models of epilepsy. Neuroscience259: 142–154
- Remus R, Wiens D (2008) The effects hypergravity on the morphology of xenopus embryos. American Journal of Undergraduate Research7(2): 19–26
- Scott GR, Johnston IA (2012) Temperature during embryonic development has persistent effects on thermal acclimation capacity in zebrafish. Proceedings of the National Academy of Sciences USA109(35): 14247–14252
- Serra EL, Medalha CC, Mattioli R (1999) Natural preference of zebrafish (Danio rerio) for a dark environment. Brazilian Journal of Medical and Biological Research32: 1551–1553
- Sfakianakis DG, Leris I, Kentouri M (2011) Effect of developmental temperature on swimming performance of zebrafish (Danio rerio) juveniles. Environmental Biology of Fishes90: 421
- Stewart A, Kadri F, DiLeo J, Chung KM, Cachat J, Goodspeed J, Suciu C, Roy S, Gaikwad S, Wong K, Elegante M, Elkhayat S, Wu N, Gilder T, Tien D, Grossman L, Tan J, Denmark A, Bartels B, Frank K, Beeson E, Kalueff A (2010). The developing utility of zebrafish in modeling neurobehavioral disorders. International Journal of Comparative Psychology23: 104–120
- Tavares B, Santos Lopes S (2013) The importance of Zebrafish in biomedical research. Acta Medica Portuguesa26: 583–592
- Tomko D, Souza K, Smith J, Mains R, Sato K, Levine H, Quincy C, Mills A, Zeituni A (2016) NASA space biology science plan 2016–2025. Available at
https://www.nasa.gov/sites/default/files/atoms/files/16-03-23_sb_plan.pdf - Trappe S, Costill D, Gallagher P, Creer A, Peters JR, Evans H, Riley DA, Fitts RH (2009) Exercise in space: human skeletal muscle after 6 months aboard the International Space Station. Journal of Applied Physiology (1985)106: 1159–1168
- Van Loon JJWA (2016) Centrifuges for microgravity simulation. The reduced gravity paradigm. Frontiers in Astronomy and Space Scences3: 21
- Wagner EB, Charles JB, Cuttino CM (2009) Opportunities for research in space life sciences aboard commercial suborbital flights. Aviation, Space, and Environmental Medicine80: 984–986
- Weichert GF, Floeter C, Meza Artmann AS, Kammann U (2017) Assessing the ecotoxicity of potentially neuorotoxic substance - evaluation of a behavioural parameter in the embryogenesis of Danio rerio. Chemosphere186: 43–50
- Westerfield M (2007) The Zebrafish Book. A Guide for the Laboratory Use of Zebrafish (Danio rerio), 5th Edition. Eugene: University of Oregon Press
- Zhou Y, Cattley RT, Cario CL, Bai Q, Burton EA (2014) Quantification of larval zebrafish motor function in multiwell plates using open-source MATLAB applications. Nature Protocols9: 1533–1548
- Zienkiewicz A, Barton DA, Porfiri M, di Bernardo M (2015) Data-driven stochastic modelling of zebrafish locomotion. Journal of Mathematical Biology71: 1081–1105