Figure 1.
Figure 2.
Figure 3.
Figure 4.
Figure 5.
Fitted value (FV) of the effective dose of radiation (ED) to decrease the cell count by 10% (ED10), 50% (ED50) and 90% (ED90) in mice exposed to SPE-like proton and/or HU_
| ED10 | ED50 | ED90 | ||||
|---|---|---|---|---|---|---|
| FV (Gy) | 95% CI* | FV (Gy) | 95% CI | FV (Gy) | 95% CI | |
| Lymphocytes | ||||||
| day-2 post-irradiation | ||||||
| No HU | 0.13 | 0.09 – 0.16 | 0.83 | 0.58 – 1.08 | 2.76 | 1.92 – 3.60 |
| HU | 0.23 | 0.09 – 0.37 | 1.49 | 0.56 – 2.41 | 4.93 | 1.87 – 8.00 |
| Granulocytes | ||||||
| day-4 post-irradiation | ||||||
| No HU | 0.24 | 0.07 – 0.40 | 1.56 | 0.48 – 2.64 | 5.19 | 1.59 – 8.79 |
| HU | 0.29 | 0.16 – 0.41 | 1.88 | 1.06 – 2.71 | 6.25 | 3.52 – 8.99 |
| Granulocytes | ||||||
| day-16 post-irradiation | ||||||
| No HU | 0.17 | 0.10 – 0.24 | 1.14 | 0.68 – 1.60 | 3.78 | 2.25 – 5.32 |
| HU | NM** | NM | NM | NM | NM | NM |
| Platelets | ||||||
| day-10 post-irradiation | ||||||
| No HU | 0.20 | 0.12 – 0.27 | 1.29 | 0.79 – 1.80 | 4.30 | 2.62 – 5.99 |
| HU | 0.19 | 0.09 – 0.28 | 1.23 | 1.59 – 1.87 | 4.09 | 1.97 – 6.24 |