Figure 1
Figure 2
Figure 3
Distribution of randomized-controlled trials (RCTs) published in Pubmed per ICD-10 mental and behavioral chapter in the last 20 years
| 1999–2003 | 2004–2008 | 2009–2013 | 2014–2018 | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ICD-10 Group | n | %(+) | Coef1 | Coef2 (95%CI) | Coef3 (95%CI) | n | %(+) | Coef1 (95%CI) | Coef2 | Coef3 (95%CI) | n | %(+) | Coef1 (95%CI) | Coef2 (95%CI) | Coef3 | n | %(+) | Coef1 (95%CI) | Coef2 (95%CI) | Coef3 (95%CI) |
| F00–F09 | 54 | 14.2% | Ref | .66** (.20;1.12) | Ref | 91 | 9.8% | −.39* (−.77; −.01) | Ref | Ref | 225 | 12.3% | −.19 (−.53;.14) | .46** (.15;.77) | Ref | 367 | 14.9% | −.01 (−.33;.32) | .81*** (.51;1.10) | Ref |
| F10–F19 | 35 | 9.2% | Ref | .73** (.20;1.25) | .18 (−.29;.66) | 55 | 5.8% | −.46 (−.92;.00) | Ref | .11 (−.28;.51) | 121 | 6.6% | −.38 (−.79;.03) | .34 (−.02;.72) | Ref | 138 | 5.6% | −.55** (−.95; −.14) | .33 (−.02;.70) | −.35* (−.65; −.06) |
| F20–F29 | 52 | 13.7% | Ref | Ref | −.19 (−.61;.22) | 170 | 18.1% | .26 (−.09;.63) | Ref | .46** (.15;.77) | 264 | 14.4% | .01 (−.34;.34) | Ref | Ref | 304 | 12.3% | −.15 (−.49;.18) | Ref | −.34** (−.58; −.11) |
| F30–F39 | 151 | 39.6% | Ref | .26* (−.09;.63) | −.19 (−.53;.14) | 377 | 40.0% | Ref | Ref | .19 (−.07;.47) | 765 | 41.7% | Ref | .26* (.06;.49) | Ref | 1033 | 41.8% | Ref | .42*** (.20;.64) | −.18 (−.37;.00) |
| F40–F48 | 46 | 12.1% | Ref | .35 (−.10;.42) | −.24 (−.67;.19) | 105 | 11.2% | −.08 (−.48;.30) | Ref | .06 (−.27;.39) | 244 | 13.3% | .04 (−.31;.40) | .40** (.10;.70) | Ref | 288 | 11.7% | −.08 (−.44;.26) | .42** (.13;.71) | −.32** (−.56; −.08) |
| F50–F59 | 35 | 9.2% | Ref | −.04 (−.53;.44) | −.18 (−.65;.28) | 120 | 12.7% | .31 (−.10;.73) | Ref | .52** (.18;.85) | 176 | 9.6% | −.01 (−.41;.39) | −.05 (−.35;.24) | Ref | 300 | 12.1% | .22 (−.16;61) | .33* (.06;.61) | .04 (−.20;29) |
| F60–F68 | 8 | 2.1% | Ref | .12 (−.73;.99) | −.13 (−.94;.68) | 23 | 2.4% | .14 (−.68;.96) | Ref | .40 (−.16;.97) | 38 | 2.1% | −.06 (−.84;.71) | .06 (−.49;.61) | Ref | 41 | 1.7% | −.28 (−1.06;.48) | −.01 (−.54;.54) | −.41 (−.88;.05) |
| F70–F79 | 0 | 0,0% | N.A. | N.A. | N.A. | 1 | 0.1% | N.A. | N.A. | N.A. | 0 | 0,0% | N.A. | N.A. | N.A. | 0 | 0,00% | N.A. | N.A. | N.A. |
| Group | n | %(#) | Coef4 | Coef5 | Coef6 | n | %(#) | Coef4 | Coef5 | Coef6 | n | %(#) | Coef4 | Coef5 | Coef6 | n | %(#) | Coef4 | Coef5 | Coef6 |
| Mental | 376 | 3.1% | Ref | −.41*** (−.53; −.29) | −.56*** (−.67; −.45) | 922 | 4.6% | .41*** (.29;.53) | Ref | −.14*** (−.23; −.06) | 1770 | 5.3% | .56*** (.45;.67) | .14*** (.06;.23) | Ref | 2381 | 5.0% | .51*** (.40;.62) | .09* (.01;.17) | −.05 (−.11;.01) |
| Pubmed (Other) | 11875 | 96.9% | Ref | Ref | Ref | 19192 | 95.4% | Ref | Ref | Ref | 31733 | 94.7% | Ref | Ref | Ref | 45034 | 95.0% | Ref | Ref | Ref |
| %(+): Within the mental and behavioral chapter; %(#): Within entire Pubmed; (95%CI): 95% Confidence Interval | ||||||||||||||||||||