Skip to main content
Have a personal or library account? Click to login
Analysis of Factors Influencing Somatic Cell Count in Dairy Cow Milk Cover

Analysis of Factors Influencing Somatic Cell Count in Dairy Cow Milk

Open Access
|Jun 2026

References

  1. 1. Watson, C. J., Oliver, C. H., Khaled, W. T., 2011: Cytokine signalling in mammary gland development. J. Repro. Immunol., 88, 2, 124–129. DOI: 10.1016/j.jri.2010.11.006
  2. 2. Alhussien, M. N., Panda, B. S. K., Dang, A. K., 2021: A comparative study on changes in total and differential milk cell counts, activity, and expression of milk phagocytes of healthy and mastitic indigenous sahiwal cows. Front. Vet. Sci., 8, 670811. DOI: 10.3389/fvets.2021.670811
  3. 3. Commission Regulation (EC) No. 853/2004, 2004: Laying down specific hygiene rules for food of animal origin. Official Journal of the European Union, L 139.
  4. 4. USDA: United States Department of Agriculture, 2002: General Specifications for Dairy Plants Approved for USDA Inspection and Grading Service.
  5. 5. Schukken, Y. H., Wilson, D. J., Welcome, F., Garrison-Tikofsky, L., Gonzalez, R. N., 2003: Monitoring udder health and milk quality using somatic cell counts. Vet. Res., 34, 5, 579–596. DOI: 10.1051/vetres:2003028
  6. 6. Walstra, P., Wouters, J. T. M., Geurts, T. J., 2005: Dairy Science and Technology. 2nd ed., CRC Press, Boca Raton, USA, 763. DOI: 10.1201/9781420028010
  7. 7. Ruegg, P. L., 2017: A 100-Year Review: Mastitis detection, management, and prevention. J. Dairy Sci., 100, 12, 10381–10397. DOI: 10.3168/jds.2017-13023
  8. 8. Stocco, G., Cipolat-Gotet, C., Stefanon, B., Zecconi, A., Francescutti, M., Mountricha, M., Summer, A., 2023: Herd and animal factors affect the variability of total and differential somatic cell count in bovine milk. J. Anim. Sci., 101, 1–10. DOI: 10.1093/jas/skac406
  9. 9. Commission Regulation (EC) No. 691/2013, 2013: Amending Regulation (EC) No. 152/2009 as regards methods of sampling and analysis. OJEU, L197/1–L197/12.
  10. 10. NRC, 2021: Nutrient Requirements of Dairy Cattle: 8th ed. National Academy Press, Washington, DC.
  11. 11. STN 57 0536, 1995: Milk – Determination of composition by infrared spectrophotometry. Bratislava: Slovak Office of Standards, Metrology and Testing.
  12. 12. STN EN ISO 13366-2, 2007: Milk — Enumeration of somatic cells — Part 2: Guidance on the operation of fluoro-opto-electronic counters. Bratislava: Slovak Office of Standards, Metrology and Testing.
  13. 13. Alhussien, M. N., Dang, A. K., 2018: Milk somatic cells, factors influencing their release, future prospects, and practical utility in dairy animals: An overview. Vet. World, 11, 5, 562–577. DOI: 10.14202/vetworld.2018.562-577
  14. 14. Koivula, M., Mäntysaari, E. A., Negussie, E., Serenius, T., 2005: Genetic and phenotypic relationships among milk yield and somatic cell count before and after clinical masti- tis. J. Dairy Sci., 88, 2, 827–833. DOI: 10.3168/jds.S0022-0302(05)72747-8
  15. 15. Olde Riekerink, R. G. M., Barkema, H. W., Kelton, D. F., Scholl, D. T., 2008: Incidence rate of clinical mastitis on Canadian dairy farms. J. Dairy Sci., 91, 4, 1366–1377. DOI: 10.3168/jds.2007-0757
  16. 16. Bach, K. D., Barbano, D. M., McArt, J. A. A., 2021: The relationship of excessive energy deficit with milk somatic cell score and clinical mastitis. J. Dairy Sci., 104, 1, 715–727. DOI: 10.3168/jds.2020-18432
  17. 17. Mondini, S., Gislon, G., Zucali, M., Sandrucci, A., Tamburini, A., Bava, L., 2025: Factors influencing somatic cell count and leukocyte composition in cow milk: A field study. J. Dairy Sci., 108, 3, 2721–2733. DOI: 10.3168/jds.2024-25357
  18. 18. Hagnestam-Nielsen, C., Emanuelson, U., Berglund, B., Strandberg, E., 2009: Relationship between somatic cell count and milk yield in different stages of lactation. J. Dairy Sci., 92, 7, 3124–3133. DOI: 10.3168/jds.2008-1719
  19. 19. Sordillo, L. M., Streicher, K. L., 2002: Mammary gland immunity and mastitis susceptibility. J. Mammary Gland Biol. Neoplasia, 7, 2, 135–146. DOI: 10.1023/a:1020347818725
  20. 20. Gao, S. T., Ma, L., Zhou, Z., Zhou, Z. K., Baumgard, L. H., Jiang, D., et al., 2019: Heat stress negatively affects the transcriptome related to overall metabolism and milk protein synthesis in mammary tissue of midlactating dairy cows. Physiol. Genomics, 51, 8, 400-409. DOI: 10.1152/physiolgenomics.00039.2019
  21. 21. Park, T., Ma, L., Gao, S., Bu, D., Yu, Z., 2022: Heat stress impacts the multi-domain ruminal microbiota and some of the functional features independent of its effect on feed in-take in lactating dairy cows. J. Anim. Sci. Biotechnol., 13, 71, 1–15. DOI: 10.1186/s40104-022-00717-z
  22. 22. Lemal, P., May, K., König, S., Schroyen, M., Gengler, N., 2023: Invited review: From heat stress to disease - Immune response and candidate genes involved in cattle thermotolerance. J. Dairy Sci., 106, 7, 4471–4488. DOI: 10.3168/jds.2022-22727
DOI: https://doi.org/10.2478/fv-2026-0019 | Journal eISSN: 2453-7837 | Journal ISSN: 0015-5748
Language: English
Page range: 75 - 80
Submitted on: Jan 12, 2026
Accepted on: Apr 9, 2026
Published on: Jun 26, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Petra Timkovičová Lacková, Iveta Maskaľová, Tomáš Mihok, Zuzana Farkašová, Michaela Harčárová, published by The University of Veterinary Medicine and Pharmacy in Košice
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.