Serological and Epizootic Dynamics of Swine Influenza a in Industrial Swine Farms of Ukraine (2021–2024)
References
- 1. Ma, W., 2020: Swine influenza virus: Current status and challenge. Virus Res., 288, 198118. DOI: 10.1016/j.virus-res.2020.198118
- 2. Anderson, T. K., Chang, J., Arendsee, Z. W., Venkatesh, D., Souza, C. K., Kimble, J. B., et al., 2021: Swine influenza A viruses and the tangled relationship with humans. Cold Spring Harb. Perspect. Med., 11, a038737. DOI: 10.1101/cshperspect.a038737
- 3. Ang, L. W., Cui, L., Mak, T. M., Ng, Y., Leo, Y. S., Lee, V. J. M., Lin, R. T.-P., 2019: Differential age-specific distribution of influenza virus types and subtypes in tropical Singapore, 2011 to 2017. J. Med. Virol., 91, 8, 1415–1422. DOI: 10.1002/jmv.25473
- 4. Kanji, J. N., Pabbaraju, K., Croxen, M., Detmer, S., Bastien, N., Li, Y., et al., 2021: Characterization of swine influenza A(H1N2) variant, Alberta, Canada, 2020. Emerg. Infect. Dis., 27, 12, 3045–3051.
- 5. Le Sage, V., Rockey, N. C., French, A. J., McBride, R., McCarthy, K. R., Rigatti, L. H., et al., 2024: Potential pandemic risk of circulating swine H1N2 influenza viruses. Nat. Commun., 15, 5025. DOI: 10.1038/s41467-024-49117-z
- 6. Mon, P. P., Thurain, K., Janetanakit, T., Nasamran, C., Bunpapong, N., Aye, A. M., et al. 2020: Swine influenza viruses and pandemic H1N1-2009 infection in pigs, Myanmar. Trans-bound. Emerg. Dis., 67, 2653–2666. DOI: 10.1111/tbed.13616
- 7. Abdelwhab, E. M., Mettenleiter, T. C., 2023: Zoonotic animal influenza virus and potential mixing vessel hosts. Viruses, 15, 4, 980. DOI: 10.3390/v15040980
- 8. Meng, F., Yang, H., Qu, Z., Chen, Y., Zhang, Y., Zhang, Y., et al., 2022: A Eurasian avian-like H1N1 swine influenza reassortant virus became pathogenic and highly transmissible due to mutations in its PA gene. Proc. Natl. Acad. Sci. USA, 119, 34, e2203919119. DOI: 10.1073/pnas.2203919119
- 9. Sun, H., Xiao, Y., Liu, J., Wang, D., Li, F., Wang, C., et al., 2020: Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection. Proc. Natl. Acad. Sci. USA, 117, 29, 17204–17210. DOI: 10.1073/pnas.1921186117
- 10. Bliss, N., Nelson, S. W., Nolting, J. M., Bowman, A. S., 2016: Prevalence of influenza A virus in exhibition swine during arrival at agricultural fairs. Zoonoses Public Health, 63, 6, 477–485. DOI: 10.1111/zph.12252
- 11. Bliss, N., Stull, J. W., Moeller, S. J., Rajala-Schultz, P. J., Bowman, A. S., 2017: Movement patterns of exhibition swine and associations of influenza A virus infection with swine management practices. J. Am. Vet. Med. Assoc., 251, 6, 706–713. DOI: 10.2460/javma.251.6.706
- 12. Nelson, M. I., Wentworth, D. E., Das, S. R., Sreevatsan, S., Killian, M. L., Nolting, J. M., et al., 2016: Evolutionary dynamics of influenza A viruses in US exhibition swine. J. Infect. Dis., 213, 2, 173–182. DOI: 10.1093/infdis/jiv399
- 13. Gopinath, S. C. B., Tang, T.-H., Chen, Y., Citartan, M., Tominaga, J., Lakshmipriya, T., 2014: Sensing strategies for influenza surveillance. Biosens. Bioelectron., 61, 357–369. DOI: 10.1016/j.bios.2014.05.024
- 14. Mollett, B. C., Everett, H. E., van Diemen, P. M., Byrne, A. M. P., Ramsay, A., James, J., et al., 2023: JMM profile: Swine influenza A virus: a neglected virus with pandemic potential. J. Med. Microbiol., 72, 1, 1–5. DOI: 10.1099/jmm.0.001623
- 15. Detmer, S., Gramer, M., Goyal, S., Torremorell, M., Torrison, J., 2012: Diagnostics and surveillance for swine influenza. Curr. Top. Microbiol. Immunol., 370, 85–112. DOI: 10.1007/82_2012_220
- 16. Graaf-Rau, A., Hennig, C., Lillie-Jaschniski, K., Koechling, M., Stadler, J., Boehmer, J., et al., 2023: Emergence of swine influenza A virus, porcine respirovirus 1 and swine orthopneumovirus in porcine respiratory disease in Germany. Emerg. Microbes Infect., 12, 2, 2239938. DOI: 10.1080/22221751.2023.2239938
- 17. Klivleyeva, N., Saktaganov, N., Glebova, T., Lukmanova, G., Ongarbayeva, N., Webby, R., 2024: Influenza A viruses in the swine population: ecology and geographical distribution. Viruses, 16, 11, 1728. DOI: 10.3390/v16111728
- 18. He, W., Zhang, W., Yan, H., Xu, H., Xie, Y., Wu, Q., et al., 2021: Distribution and evolution of H1N1 influenza A viruses with adamantanes-resistant mutations worldwide from 1918 to 2019. J. Med. Virol., 93, 6, 3473–3483. DOI: 10.1002/jmv.26670
- 19. Brown, I. H., 2013: History and epidemiology of swine influenza in Europe. Curr. Top. Microbiol. Immunol., 370, 133–146. DOI: 10.1007/82_2011_194
- +T., Reeth, K. V., et al., 2014: European surveillance network for influenza in pigs: surveillance programs, diagnostic tools and swine influenza virus subtypes identified in 14 european countries from 2010 to 2013. PLoS One, 9, 12, e115815. DOI: 10.1371/journal.pone.0115815
- 21. Lewis, N. S., Russell, C. A., Langat, P., Anderson, T. K., Berger, K., Bielejec, F., et al., 2016: The global antigenic diversity of swine influenza A viruses. eLife, 5, e12217. DOI: 10.7554/eLife.12217
- 22. Stegniy, B. T., Rula, O. M., Muzyka, N. M., Dunaiev, Yu. K., Busol, V. O., Kolchyk, O. V., Muzyka, D. V., 2023: Risk of swine influenza for veterinary medicine and human health in Ukraine. J. Vet. Med. Biotechnol. Biosafety, 9, 3, 33–41. DOI: 10.36016/JVMBBS-2023-9-3-6
- 23. Zell, R., Groth, M., Krumbholz, A., Lange, J., Philipps, A., Dürrwald, R., 2020: Cocirculation of swine H1N1 influenza A virus lineages in Germany. Viruses, 12, 7, 762. DOI: 10.3390/v12070762
- 24. Trombetta, C. M., Montomoli, E., Di Bartolo, I., Ostanello, F., Chiapponi, C., Marchi, S., 2022: Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004. J. Med. Virol., 94, 6, 2855–2859. DOI: 10.1002/jmv.27466
- 25. Van Reeth, K., Brown, I. H., Dürrwald, R., Foni, E., Labarque, G., Lenihan, P., et al., 2008: Seroprevalence of H1N1, H3N2 and H1N2 influenza viruses in pigs in seven European countries in 2002–2003. Influenza Other Respir. Viruses, 2, 3, 99–105. DOI: 10.1111/j.1750-2659.2008.00043.x
- 26. Bakre, A. A., Jones, L. P., Kyriakis, C. S., Hanson, J. M., Bobbitt, D. E., Bennett, H. K., et al., 2020: Molecular epidemiology and glycomics of swine influenza viruses circulating in commercial swine farms in the southeastern and midwest United States. Vet. Microbiol., 251, 108914. DOI: 10.1016/j.vetmic.2020.108914
- 27. Fraiha, A. L. S., Matos, A. C. D., Cunha, J. L. R., Santos, B. S. Á., da S., Peixoto, M. V. C., Oliveira, A. G. G., et al., 2021: Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019. Braz. J. Microbiol., 52, 2421–2430. DOI: 10.1007/s42770-021-00550-y
- 28. López-Robles, G., Montalvo-Corral, M., Burgara-Estrella, A., Hernández, J., 2014: Serological and molecular prevalence of swine influenza virus on farms in northwestern Mexico. Vet. Microbiol., 172, 323–328. DOI: 10.1016/j.vetmic.2014.05.017
- 29. Gonzalez‐Reiche, A. S., Ramírez, A. L., Müller, M. L., Orellana, D., Sosa, S. M., Ola, P., et al., 2017: Origin, distribution, and potential risk factors associated with influenza A virus in swine in two production systems in Guatemala. Influenza Other Respir. Viruses, 11, 2, 182–192. DOI: 10.1111/irv.12437
- 30. Li, Y., Edwards, J., Wang, Y., Zhang, G., Cai, C., Zhao, M., et al., 2019: Prevalence, distribution and risk factors of farmer reported swine influenza infection in Guangdong Province, China. Prev. Vet. Med., 167, 1–8. DOI: 10.1016/j. prevetmed.2019.03.011
- 31. Zhao, Y., Han, L., Chen, T., Sang, H., Ding, G., Li, Y., et al., 2022: Serological surveillance of the H1N1 and H3N2 swine influenza A virus in chinese swine between 2016 and 2021. Biomed. Res. Int., 2022, 5833769, 1–8. DOI: 10.1155/2022/5833769
- 32. El Zowalaty, M. E., Abdelgadir, A., Borkenhagen, L. K., Ducatez, M. F., Bailey, E. S., Gray, G. C., 2022: Influenza A viruses are likely highly prevalent in South African swine farms. Transbound. Emerg. Dis., 69, 2373–2383. DOI: 10.1111/tbed.14255
- 33. Baudon, E., Peyre, M., Peiris, M., Cowling, B. J., 2017: Epidemiological features of influenza circulation in swine populations: A systematic review and meta-analysis. PLoS One, 12, 6, e0179044. DOI: 10.1371/journal.pone.0179044
- 34. Senthilkumar, D., Kulkarni, D. D., Venkatesh, G., Gupta, V., Patel, P., Dixit, M., et al., 2021: Widespread prevalence of antibodies against swine influenza A (pdm H1N1 09) virus in pigs of eastern Uttar Pradesh, India. Curr. Microbiol., 78, 2753–2761. DOI: 10.1007/s00284-021-02520-x
- 35. Harima, H., Okuya, K., Kajihara, M., Ogawa, H., Simulundu, E., Bwalya, E., et al., 2022: Serological and molecular epidemiological study on swine influenza in Zambia. Transbound. Emerg. Dis., 69, e931–e943. DOI: 10.1111/tbed.14373
Language: English
Page range: 60 - 66
Submitted on: Jan 9, 2026
Accepted on: Feb 25, 2026
Published on: Jun 26, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
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© 2026 Anatolii Kovalenko, Jana Mojžišová Vaščinec, Vasil Koziy, Nataliia Kozii, Boris Vojtek, Anna Ondrejková, Silvia Kapľavka, Ľuboš Korytár, Marián Prokeš, Monika Drážovská, published by The University of Veterinary Medicine and Pharmacy in Košice
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