Correlations between Sodium Selenite and Vitamin E with Serum Macro-Minerals in Male Lambs

The effects of selenium and vitamin E (Vit. E) were evaluated on the macro-elements and their relationships were also surveyed. Lambs were divided into 4 groups of control, Vit. E, sodium selenite and sodium selenite/Vit. E (Se/E). Sodium selenite (0.1 mg.kg⁻¹) and Vit. E (8 mg.kg⁻¹) were administered. The mean blood selenium was high in sodium selenite. Selenium only in the Se groups was continuously increased. The lowest and highest blood selenium were in Vit. E and sodium selenite, respectively. The mean serum macro-minerals were within the normal range. The trend of calcium and magnesium in the selenium groups was to increase until day 60, but phosphorus was to decline. The lowest and highest calcium were observed in the control and sodium selenite groups, for magnesium in Vit. E and control groups, and for inorganic phosphorus were in the control group, respectively. The comparison of minerals showed that selenium had a significant increase from day 14 to 90 in sodium selenite. Selenium showed the most positive relationships with calcium and inorganic phosphorus in Vit. E and sodium selenite. Overall, selenium was correlated with macro-minerals on day 90 and overall sampling times were with calcium. In conclusion, administration of selenium with Vit. E increased selenium, which was more observed in the sodium selenite group. Sodium selenite alone or with Vit. E had no effect on the macro-minerals. The least correlation was observed between selenium and macro-minerals in the Se/E administration. The correlation between macro-minerals was positive. It was concluded that the effect of sodium selenite on treatment and prevention of selenium deficiency was more effective than other groups. Vit. E per selenium did not change the selenium concentration. Selenium administration was associated with an increase in calcium level and their co-administration is recommended.