References
- 1. Adams, C., Pitzer, J., Minion, F. C., 2005:In vivo expression analysis of the P97 and P102 paralog families of Mycoplasma hyopneumoniae. Infect. Immun., 73, 11, 7784—7787. DOI:10.1128/IAI.73.11.
- 2. Amanfu, W., Weng, C. N., Ross, R. F., Barnes, H. J., 1984: Diagnosis of mycoplasmal pneumonia of swine: Sequential study by direct immunofluorescence. Am. J. Vet. Res., 45, 1349—1352.
- 3.Asai, T., Okada, M., Ono, M., Mori, Y., Yokomiso, Y., Sato, S., 1994: Detection of interleukin-6 and prostaglandin E2 in broncho-alveolar larvage fluids of pigs experimentally infected with Myco - plasma hyopneumoniae. Vet. Immun. Immunopathol., 44, 97—102.10.1016/0165-2427(94)90172-4
- 4. Blanchard B., Vena, M. M., Cavalier A., Lannic J. I., Gouranton, J., Kobisch, M., Le-Lannic J., 1992: Election microscopic observation of the respiratory tract of SPF-piglet inoculated with Mycoplasma hyopneumoniae. Vet. Microbiol., 30, 329—341.10.1016/0378-1135(92)90020-T
- 5. Brockmeier, S., Halbur, P., Thacker, E., 2003: Porcine respiratory disease complex. In Brogden, K. A., Guthmiller, J. M. (Eds.):Polymicrobial Diseases. ASM Press, Washington DC, 231—258.10.1128/9781555817947.ch13
- 6. Chae, C., 2016: Porcine respiratory disease complex: Interaction of vaccination and porcine circovirus type 2, porcine reproductive and respiratory syndrome virus, and Myco-plasma hyopneumoniae. Vet. J., 212, 1—6. DOI: 10.1016/j. tvjl.2015.10.030.
- 7. Cheville, N. F., Stasko J., 2014: Techniques in electron microscopy of animal tissues. Vet. Pathol., 51, 1, 28—41. DOI: 10.1177/0300985813505114.10.1177/0300985813505114
- 8. Choi, C., Kwon, D., Jung, K., Ha, Y., Lee, Y. H., Kim, O., et al., 2006: Expression of inflammatory cytokines in pigs experimentally infected with Mycoplasma hyopneumoniae. J. Comp. Pathol., 134, 1, 40—46. DOI: 10.1016/j.jcpa.2005.06.009.10.1016/j.jcpa.2005.06.009
- 9. Christensen, N. H., 1995: Evaluation of the effects of enzootic pneumonia in pigs on weight gain and days to slaughter under New Zealand conditions. N. Z. Vet. J., 43, 4, 146—148.10.1080/00480169.1995.35875
- 10. Collier A. M., 1983: Attachment by mycoplasmas and its role in disease. Rev. Infect. Dis., 5, S685–S691.10.1093/clinids/5.Supplement_4.S685
- 11. DeBey, M. C., Ross, R. F., 1994: Ciliostasis and loss of cilia induced by Mycoplasma hyopneumoniae in porcine tracheal organ cultures. Infect. Immun., 62, 5312—5318. DOI: 0019-9569/94/$04.00+0.10.1128/iai.62.12.5312-5318.1994
- 12. DeBey, M. C., Jaboson, C. D., Ross, R. F., 1992: Histochemical and morphologic changes of porcine airway epithelial cells in response to infection with Mycoplasma hyopneumoniae. Am. J. Vet. Res., 53, 1705—1710.
- 13. Enoe, C., Mousing, J., Schirmer, A. L., Willeberg, P., 2002: Infectious and rearing system related risk factors for chronic pleuritis in slaughter pigs. Prev. Vet. Med., 54, 337—349. DOI: 10.1016/S0167-5877(02)00029-6.10.1016/S0167-5877(02)00029-6
- 14. Hansen, M. S., Pors, S. E., Jensen, H. E., Bille-Hansen, V., Bisguard, M., Flachs, E. M., Nielsen, O. L., 2010: An investigation of the pathology and pathogens associated with porcine respiratory disease complex in Denmark. J. Comp. Path., 143, 120—131. DOI: 10.1016/j.jcpa.2010.01.012.10.1016/j.jcpa.2010.01.012709441520181357
- 15. Hsu, T., Minion, F. C., 1998: Identification of the Cilium Binding Epitope of the Mycoplasma hyopneumoniae P97 adhesin. Infect. Immun., 66, 10, 4762—4766. DOI: 0019-9567/98/$04.00+0.10.1128/IAI.66.10.4762-4766.19981085879746576
- 16. Hsu, T., Artiushin S., Minion, F. C., 1997: Cloning and analysis of P97, a respiratory cilium adhesin gene of Mycoplasma hyopneumoniae. J. Bacteriol., 179, 1317—1323. DOI: 10.1128/jb.179.4.1317-1323.1997.10.1128/jb.179.4.1317-1323.19971788319023217
- 17. Irigoyen, L. F., Van Alstine, W., Turek, J., Clark, L. K., 1998: Ultrastructural observation of the airways of recovered and susceptible pigs after inoculation with Mycoplasma hyopneumonie. Pesquisa Veterinária Brasileira, 18, 1, 1—7. DOI: 10.1590/S0100-736X1998000100001.10.1590/S0100-736X1998000100001
- 18. Kwon, D., Chae, C., 1999: Detection and localization of Mycoplasma hyopneumoniae DNA in lungs from naturally infected pigs by in-situ hybridization using digoxigenin-labeled probe. Vet. Pathol., 36, 4, 306–313. DOI: 10.1354/vp.36-4-308.10.1354/vp.36-4-30810421097
- 19. Kwon, D. Choi, C., Chae, C., 2002: Chronologic localization of Mycoplasma hyopneumoniae in experimentally infected pigs. Vet. Pathol., 39, 5, 584—587. DOI: 10.1354/vp.39-5-584.10.1354/vp.39-5-58412243470
- 20. Kyriakis, S. C., Alexopoulos, C., Vlemmas, J., Sarris, K., Lekkas, S., Koutsoviti-Papadopoulou, M., Saoulidis, K., 2001: Field study on the efficacy of two different vaccination schedules with HYORESP in a Mycoplasma hyopneumoniae infected commercial pig unit. J. Vet. Med. B. Inf. Dis. Vet. Public Health, 48, 675—684.10.1046/j.1439-0450.2001.00494.x11765803
- 21. Lorenzo, H., Quesada, O., Assuncao, P., Castro, A., Rodriguez, F., 2006: Cytokine expression in porcine lungs experimentally infected with Mycoplasma hyopneumoniae. Vet. Immunol. Immunopathol., 109, 3—4, 199—207. DOI: 10.1016/j. vetimm.2005.07.021.
- 22. Maes, D., Sibila, M., Kuhnert, P., Segalés, J., Haesebrouck, F., Pieters, M., 2018: Update on Mycoplasma hyopneumoniae infections in pigs: knowledge gaps for improved disease control. Transbound Emerg. Dis., 65 (Suppl.1), 110—124. DOI: 10.1111/tbed.12677.10.1111/tbed.1267728834294
- 23. Maes, D., Verdonck, M., Deluyker, H., de Kruif, A., 1996: Enzootic pneumonia in pigs. Vet. Quarterly, 18, 3, 104—109. DOI: 10.1080/01652176.1996.9694628.10.1080/01652176.1996.96946288903144
- 24. Merialdi, G., Dottori, M., Bonilauri, P., Luppi, A., Gozio, S., Pozzi, P., et al., 2012: Survey of pleuritis and pulmonary lesions in pigs at abattoir with a focus on the extent of the condition and herd risk factors. Vet. J., 193, 234—239.10.1016/j.tvjl.2011.11.00922182431
- 25. Messier, S., Ross, R. F., Paul, P. S., 1990: Humoral and cellular immune response of pigs inoculated with Mycoplasma hyopneumoniae. Am. J. Vet. Res., 51, 52—58.
- 26. Minion, F. C., Elliot, J. L., Melissa, L. M., Barbara, J. C., Steven, M. S., Gregory, G. M., 2004: The genome sequence of Mycoplasma hyopneumoniae strain 232, the agent of swine mycoplasmosis. J. Bacteriol., 186, 21, 7123—7133. DOI: 10.1128/JB.186.21.7123-7133.2004.10.1128/JB.186.21.7123-7133.200452320115489423
- 27. Minion, F. C., Adams, C., Hsu, T., 2000: R1 region mediates adherence of Mycoplasma hyopneumoniae to swine cilia. Inf. Immun., 68, 5, 3056—3060. DOI: 10.1128/IAI.68.5.3056-3060.2000.10.1128/IAI.68.5.3056-3060.20009753010769015
- 28. Myens, T., Maes, D., Calus, D., Ribbens, S., Dewulf, J., Chiers, K., et al., 2007: Interactions of highly and low virulent Mycoplasma hyopneumoniae isolates with the respiratory tract of pigs. Vet. Microbiol., 120, 87—95. DOI: 10.1016/j.vetmic.2006.10.010.10.1016/j.vetmic.2006.10.01017123752
- 29. Nathues, H., Chang, Y. M., Wieland, B., Rechter, G., Spergser, J., Rosengarten, R, L. et al., 2014: Herd-level risk factors for the seropositivity to Mycoplasma hyopneumoniae and the occurrence of enzootic pneumonia among fattening pigs in areas of endemic infection and high pig density. Transbound. Emerg. Dis., 61, 316—328. DOI:10.1111/tbed.12033.10.1111/tbed.1203323199301
- 30. Opriessnig, T., Thacker, E. L., Yu, S., Fenaux, M., Meng, X. J., Halbur, P. G., 2004: Experimental re-production of postweaning multisystemic wasting syndrome in pigs by dual infection with Mycoplasma hyopneumoniae and porcine circovirus type 2, Vet. Pathol., 41, 624—640. DOI: 10.1354/vp.41-6-624.10.1354/vp.41-6-62415557072
- 31. Opriessnig, T., Giménez-Lirola, L. G., Halbur, P. G., 2011: Polymicrobial respiratory disease in pigs. Anim. Health Res. Rev., 12, 133—148. DOI: 10.1017/S1466252311000120.10.1017/S146625231100012022152290
- 32. Ostanello, F., Dottori, M., Gusmara, C., Leotti, G., Sala, V., 2007: Pneumonia disease assessment using a slaughterhouse lung-scoring method. J. Vet. Med. A. Physiol. Pathol. Clin. Med., 54, 70—75.10.1111/j.1439-0442.2007.00920.x17305969
- 33. Park, C., Jeong, J., Kang, I., Choi, K., Park, S., Chae, C. 2016: Increased fucosyl glycoconjugate by Mycoplasma hyopneumoniae enhances adherence of Pasteurella multocida type A in the ciliated epithelial cells of the respiratory tract. BMC Vet. Res., 12, 25—31. DOI: 10.1186/s12917-016-0650-7.10.1186/s12917-016-0650-7473878326841756
- 34. Pinto, P., de Carvalho, M., Alves-Junior, L., Brocchi, M., Schrank, I. S., 2007: Molecular analysis of an integrative conjugative element, ICEH, present in the chromosome of different strains of Mycoplasma hyopneumoniae. Genet. Mol. Biol., 30, 256—263.10.1590/S1415-47572007000200014
- 35. Pointon, A., Byrt, M., Heap, P., 1985: Effect of enzootic pneumonia of pigs on growth performance. Aust Vet. J., 62, 13—18.10.1111/j.1751-0813.1985.tb06032.x3924012
- 36. Raymond, B. B. A., Turnbull, L., Jenkins, C., Madhkoor, R. I., Schleicher, I., Uphoff. C. C., et al., 2018:Mycoplasma hyopneumoniae resides intracellularly within porcine epithelial cells. Nature Sci. Rep., 8, 17697. DOI:10.1038/s41598-018-36054-3.10.1038/s41598-018-36054-3628384630523267
- 37. Redondo, F., Masot, A. J., Fernandez, A. and Gazquez, A. 2009: Histopathological and immunohistochemical findings in the lung of pigs infected experimentally with Mycoplasma hyopneumoniae. J. Comp. Pathol., 140, 260—270. DOI: 10.1016/j.jcpa.2008.12.008.10.1016/j.jcpa.2008.12.008
- 38. Sarradell, J., Andrada, M., Ramirez, A. S., Fernandez, A., Gomez-Villamandos, J. C., Jover, A. 2003: A morphologic and immunohistochemical study of the bronchus associated lymphoid tissue of pigs naturally infected with Mycoplasma hyopneumoniae. Vet. Pathol., 40, 395—404. DOI: 10.1354/vp.40-4-395.10.1354/vp.40-4-395
- 39. Straw, B. E., Tuovinen, V. K., Bigras-Poulin, M., 1989: Estimation of the cost of pneumonia in swine herds. J. Am. Vet. Med. Assoc., 195, 1702—1706.
- 40. Thacker, E. L., 2004: Diagnosis of Mycoplasma hyopneumoniae. Anim. Health Res. Rev., 5, 317—320. DOI: 10.1079/AHR200491.10.1079/AHR200491
- 41. Thacker, E. L., Minion, F. C., 2012: Mycoplasmosis. In Zimmerman, J. J., Ramirez, A., Schwartz, K. J., Stevenson, G. W. (Eds.): Diseases of Swine, 10th edn., Wiley-Blackwell, Ames, 779—798.
- 42. Thomsen, B. L., Jorsal, S. E., Andersen, S., Willrhrrg, P., 1992: The Cox regression model applied to risk factor analysis of infections in the breeding and multiplying herds in the Danish SPF system. Prev. Vet. Med., 12, 287—197.10.1016/0167-5877(92)90056-L
- 43. Van Reeth, K., Nauwynck, H., 2000: Pro-inflammatory cytokines and viral respiratory disease in pigs. Vet. Res., 31, 187—213.10.1051/vetres:2000113
- 44. Vicca, J., Stakenborg, T., Maes, D., Butaye, P., Peeters, J., de Kruif, A., Haesebrouck, F., 2003: Evaluation of virulence of Mycoplasma hyopneumoniae field isolates. Vet. Microbiol., 97, 177—190. DOI: 10.1016/j.vetmic.2003.08.008.10.1016/j.vetmic.2003.08.008
- 45. Young, T., Thacker, E. L., Ericson, B. Z., Ross, R. F., 2000: A tissue culture system of studying respiratory ciliary epithelia adherence of selected swine mycoplasmas. Vet. Microbiol., 71, 269—279. DOI: 10.1016/S0378-1135(99)00176-5.10.1016/S0378-1135(99)00176-5
- 46. Zhang, Q., Young, T. F., Ross., R. F., 1995: Identification and characterization of a Mycoplasma hyopneumoniae adhesin. Infect. Immunun., 63, 3, 1013—1019. DOI: 0019-9567/95/$04.00+0.10.1128/iai.63.3.1013-1019.19951731037868222
- 47. Zhang, Q., Young, T. F., Ross, R. F., 1994: Glycolipid receptors for attachment of Mycoplasma hyopneumoniae to porcine respiratory ciliated cells. Infect. Immun., 62, 10, 4367—4373. DOI: 0019-9567/94/$04.00+0.10.1128/iai.62.10.4367-4373.19943031187927697
- 48. Zielinski, G. C., Ross, R. F., 1992: Morphologic features and hydrophobicity of the cell surface of Mycoplasma hyopneumoniae. Am. J. Vet. Res., 53, 1119—1124.