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Risk factors for safe injection practice performance among nurses in general hospitals Cover

Risk factors for safe injection practice performance among nurses in general hospitals

Open Access
|Jan 2026

Figures & Tables

Differences in performance of safe injection practices by participants’ characteristics (N = 215)_

Variables and categoriesN (%)Mean ± SDt/F (P-value)
Sex –1.63 (0.124)
   Male15 (7.0)4.09 ± 0.80
   Female200 (93.0)4.43 ± 0.49
Age (years) 1.83 (0.201)
   ≤2539 (18.1)4.33 ± 0.41
   26–2968 (31.6)4.51 ± 0.45
   30–3990 (41.9)4.35 ± 0.61
   ≥4018 (8.4)4.47 ± 0.46
Marital status –0.26 (0.791)
   Unmarried154 (71.6)4.40 ± 0.52
   Married61 (28.4)4.42 ± 0.53
Education level 0.89 (0.412)
   College20 (9.3)4.47 ± 0.46
   University181 (84.2)4.39 ± 0.54
   ≥Graduate school14 (6.5)4.56 ± 0.38
Total clinical career (years) 1.09 (0.355)
   <364 (29.8)4.41 ± 0.44
   3–547 (21.9)4.31 ± 0.70
   5–1053 (24.7)4.39 ± 0.47
   ≥1051 (23.6)4.50 ± 0.46
Position –1.40 (0.164)
   Staff nurse200 (93.0)4.39 ± 0.53
   ≥Charge Nurse15 (7.0)4.59 ± 0.33
Working department 3.25 (0.023), a < b
   Medical Unit a63 (29.3)4.24 ± 0.62
   Surgical Unit b112 (52.1)4.49 ± 0.45
   Comprehensive Nursing Care Unit12 (5.6)4.45 ± 0.53
   Special Unit28 (13.0)4.43 ± 0.47
Hospital size (number of beds) 1.45 (0.230)
   ≤30017 (7.9)4.24 ± 0.50
   301–50082 (38.1)4.49 ± 0.41
   501–100063 (29.3)4.39 ± 0.56
   >100053 (24.7)4.36 ± 0.62
Type of hospital 2.64 (0.010)
   Public hospital149 (69.3)4.48 ± 0.43
   Private hospital66 (30.7)4.24 ± 0.66
Number of patients per nurse 18.94 (<0.001), d < a, b, c
   <10a88 (40.9)4.58 ± 0.36
   10–14b47 (21.9)4.48 ± 0.39
   15–19c60 (27.9)4.31 ± 0.53
   ≥20d20 (9.3)3.74 ± 0.74
Weekly duty hours 5.63 (0.001), c < a, b
   ≤40a86 (40.0)4.50 ± 0.43
   41–47b54 (25.1)4.50 ± 0.38
   ≥48c75 (34.9)4.22 ± 0.65
Guidelines for safe injection practice in the hospital 2.06 (0.041)
   Yes185 (86.0)4.43 ± 0.52
   No30 (14.0)4.22 ± 0.46

Level of performance and knowledge of safe injection practice and perception of patient safety culture_

VariablesMean ± SDRange
Performance of safe injection practice4.40 ± 0.522.87–5.00
   Hand hygiene4.64 ± 0.572.50–5.00
   Intravenous medication4.45 ± 0.652.60–5.00
   Multi-dose vial4.19 ± 0.692.40–5.00
   Single dose vial4.27 ± 1.151.00–5.00
   Intravenous equipment4.48 ± 0.502.56–5.00
Knowledge of safe injection practice24.22 ± 3.993.00–29.00
   Hand hygiene1.95 ± 0.280.00–2.00
   Intravenous medication7.56 ± 1.431.00–9.00
   Multi-dose vial4.14 ± 0.920.00–5.00
   Single dose vial1.77 ± 0.461.00–2.00
   Intravenous equipment8.80 ± 1.721.00–11.00
Perception of patient safety culture3.72 ± 0.602.37–4.96
   Leadership3.92 ± 0.682.00–5.00
   Teamwork3.95 ± 0.632.17–5.00
   Patient safety knowledge and attitude4.13 ± 0.612.40–5.00
   Patient safety policy and procedure3.85 ± 0.732.00–5.00
   Non-punitive environment3.38 ± 1.031.00–5.00
   Patient safety improvement system3.67 ± 0.722.00–5.00
   Patient safety priority3.16 ± 0.921.00–5.00

Risk factors for the performance of safe injection practices_

Variables and categoriesBSEβtP-value
Working department (Ref. medical unit)
   Surgical unit0.040.060.040.670.503
   Comprehensive0.040.110.020.320.746
   Nursing care unit
   Special unit–0.040.08–0.02–0.430.671
   Type of hospital (Ref. public hospital) Private hospital0.010.080.010.120.902
Number of patients per nurse (Ref. <10)
   10–140.000.070.000.040.965
   15–19–0.080.07–0.07–1.170.245
   ≥20–0.020.10–0.01–0.170.864
Weekly duty hours (Ref. ≤40)
   41–47–0.070.06–0.06–1.140.254
   ≥48–0.170.08–0.16–2.090.038
Guidelines for safe injection practice in the work setting (Ref. yes)
   No0.010.070.010.160.874
Perception of patient safety culture
   Leadership0.040.070.050.510.613
   Teamwork0.130.080.161.600.111
   Knowledge/attitude0.020.070.020.220.825
   Policy/procedure–0.080.07–0.12–1.210.228
   Non-punitive environment0.020.030.040.720.474
   Improvement system0.020.050.020.330.742
   Patient safety priority0.070.040.132.020.044
   Knowledge of safe injection practice0.080.010.6311.69<0.001

Correlation between performance and knowledge of safe injection practice and perception of patient safety culture_

Variables123456789
Performance of safe injection practice (1)1
Knowledge of safe injection practice (2)0.75***1
Perception of patient safety culture (3)0.49***0.35***1
Leadership (4)0.45***0.33***0.88***1
Teamwork (5)0.47***0.35***0.87***0.85***1
Knowledge and attitude (6)0.49***0.43***0.81***0.77***0.82***1
Policy and procedure (7)0.35***0.23**0.86***0.80***0.83***0.75***1
Non-punitive environment (8)0.36***0.27***0.70***0.46***0.41***0.40***0.39***1
Improvement system (9)0.33***0.23**0.79***0.73***0.71***0.68***0.76***0.34***1
Patient safety priority (10)0.30***0.17*0.72***0.47***0.46***0.37***0.47***0.63***0.39***
DOI: https://doi.org/10.2478/fon-2025-0059 | Journal eISSN: 2544-8994 | Journal ISSN: 2097-5368
Language: English
Page range: 537 - 546
Submitted on: Nov 18, 2024
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Accepted on: Dec 18, 2024
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Published on: Jan 27, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Hyeon Jin Jang, Soonyoung Shon, Inah Kim, Mi-So Shim, published by Shanxi Medical Periodical Press
This work is licensed under the Creative Commons Attribution 4.0 License.