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Knowledge, attitude, and behavior of human papillomavirus vaccination among undergraduate students in Shanghai, China Cover

Knowledge, attitude, and behavior of human papillomavirus vaccination among undergraduate students in Shanghai, China

By: Rong-Rong Zhang and  Yan Xu  
Open Access
|Mar 2025

Figures & Tables

Factors predicting willingness to receive and promote HPV vaccine in the future_

FactorsBSEβtP
Constant15.4031.962 7.8510
Age (years)0.0970.1110.0360.8720.383
Gender–0.3340.240–0.036–1.3950.163
Year of study0.0140.1400.0040.0980.922
Heard of cervical cancer0.9020.1990.1234.5260
Heard of HPV0.5050.2600.0511.9450.052
Worried about the risk of cervical cancer1.5110.1810.2218.3320
Heard of HPV vaccine0.1300.3090.0110.4220.673
Friends or families received HPV vaccine0.4560.2550.0471.7870.074
Knowledge0.0210.0510.0110.4040.687

Correct responses to knowledge of HPV among health science and non-health science undergraduates (N = 1448)_

QuestionsOverall(n = 1448), n (%)Health science(n = 712), n (%)Non-health science(n = 712), n (%)χ2 (P value)
Q1438 (30.2)269 (37.8)169 (23.0)37.667 (0.000)
Q2853 (58.9)469 (65.9)384 (52.2)28.048 (0.000)
Q3418 (28.9)230 (32.3)188 (25.5)8.054 (0.005)
Q4351 (24.2)261 (36.7)90 (12.2)117.605 (0.000)
Q5337 (23.3)167 (23.5)195 (26.5)1.783 (0.183)
Q61115 (77.0)611 (85.8)504 (68.5)61.422 (0.000)
Q71139 (78.7)587 (82.4)552 (75.0)11.946 (0.001)
Q8474 (32.7)231 (32.4)243 (33.3)0.054 (0.816)
Q91111 (76.7)567 (79.6)544 (73.9)6.635 (0.010)
Q101043 (72.0)539 (75.7)504 (68.5)9.374 (0.002)
Total knowledge score (M ± SD)5.027 ± 1.6705.486 ± 1.6314.583 ± 1.647

Factors influencing undergraduates’ attitude toward HPV vaccination_

FactorsM ± SDd.f.FP
Gender 286.7997.6130.13
  Male14.770 ± 2.553
  Female14.455 ± 2.891
Age group (years) 14460.0330.119
  >1814.674 ± 2.609
  ≤1814.962 ± 2.560
Major 14462.8480.241
  Health science14.803 ± 2.602
  Non-health science14.643 ± 2.615
Year of study 3/14444.4840.004
  Year 115.048 ± 2.667
  Year 214.740 ± 2.600
  Year 314.411 ± 2.527
  Year 414.497 ± 2.575
Heard of cervical cancer 14460.0230
  Yes14.816 ± 2.607
  No14.095 ± 2.541
Heard of HPV 732.8344.40.028
  Yes14.965 ± 2.771
  No14.621 ± 2.522
Worried about the risk of cervical cancer 14460.2830.247
  Yes14.819 ± 2.608
  No14.657 ± 2.609
Heard of HPV vaccine 14461.2280.913
  Yes14.746 ± 2.851
  No14.719 ± 2.586
Received pay-by-self vaccine before 14460.0150.505
  Yes14.791 ± 2.586
  No14.691 ± 2.620
Friends or families received HPV vaccine 240.9346.240.059
  Yes15.092 ± 2.994
  No14.664 ± 2.540
Yourself received HPV vaccine 14462.380.16
  Yes14.091 ± 3.126
  No14.736 ± 2.595

Spearman’s correlation coefficient for demographic characteristics, HPV vaccine knowledge, attitude, and behavior_

Items1234567891011121314
1. Age (years)1
2. Gender0.0431
3. Major0.021–0.218**1
4. Year of study0.809**–0.126**0.123**1
5. Heard of cervical cancer–0.081**–0.158**–0.096**0.145**1
6. Heard of HPV–0.095**0.008–0.0120.190**0.197**1
7. Worried about cervical cancer–0.126**–0.205**0.071**0.212**0.186**0.167**1
8. Heard of HPV vaccine–0.058*–0.057*0.063*0.103**0.055*0.221**0.150**1
9. Received pay-by-self vaccine before0.054*–0.0230.037–0.086**0.026–0.086**–0.0030.073**1
10. Friends or families received the HPV vaccine–0.0130.0050.094*0.088**0.064*0.250**0.124**0.186**0.077**1
11. Received HPV vaccine–0.0130.0250.048–0.057*–0.0370.064*0.056*0.150**0.141**0.264**1
12. HPV knowledge–0.003–0.038–0.031–0.100**0.164**0.122**0.081**–0.022–0.014–0.0050.0081
13. HPV attitude0.041–0.044–0.266**0.212**0.093**0.060*0.030.0030.0180.056*–0.0370.058*1
14. HPV behavior0.102*–0.093**0.0320.121**0.132**0.190**0.274**0.087**0.0220.112**0.0310.062*–0.0471

Awareness rate of HPV and related questions among health science and non-health science undergraduates (N = 1448)_

QuestionsOverall (n = 1448), n (%)Health science (n = 712), n (%)Non-health science (n = 712), n (%)χ2 (P value)
Heard about cervical cancer
  Yes1258 (86.9)642 (90.2)616 (83.7)13.301 (0.000)
  No190 (13.1)70 (9.8)120 (16.3)
Worried about the risk of cervical cancer
  Yes425 (29.4)258 (36.2)318 (43.2)7.340 (0.007)
  No1023 (70.6)454 (63.8)418 (56.8)
Heard about HPV
  Yes576 (39.8)213 (29.9)212 (28.8)0.216 (0.642)
  No872 (60.2)499 (70.1)524 (71.2)
Heard about HPV vaccines
  Yes126 (8.7)49 (6.9)77 (10.5)5.838 (0.016)
  No1322 (91.3)663 (93.1)659 (89.5)
Yourself received HPV vaccine
  Yes33 (2.3)11 (1.5)22 (3.0)3.389 (0.066)
  No1415 (97.7)701 (98.5)714 (97.0)

Sample characteristics (N = 1448)_

Social and demographic characteristicsN (%)
Gender
  Female1226 (84.7)
  Male222 (15.3)
Age (year), mean ± SD: 19.76 ± 1.25
Major
  Health science712 (49.2)
  Non-health science736 (50.8)
Study year
  Freshman442 (30.5)
  Sophomore465 (32.1)
  Junior360 (24.9)
  Senior181 (12.5)
Heard about cervical cancer
  Yes1258 (86.9)
  No190 (13.1)
Worried about the risk of cervical cancer
  Yes425 (29.4)
  No1023 (70.6)
Heard about HPV
  Yes576 (39.8)
  No872 (60.2)
Heard about HPV vaccine
  Yes126 (8.7)
  No1322 (91.3)
Receive pay-by-self vaccine before
  Yes440 (30.4)
  No1008 (69.6)
Friends or families received HPV vaccines
  Yes196 (13.5)
  No1252 (86.5)
Yourself received HPV vaccine
  Yes33 (2.3)
  No1415 (97.7)
DOI: https://doi.org/10.2478/fon-2025-0006 | Journal eISSN: 2544-8994 | Journal ISSN: 2097-5368
Language: English
Page range: 47 - 55
Submitted on: Jan 20, 2024
Accepted on: Mar 25, 2024
Published on: Mar 14, 2025
Published by: Shanxi Medical Periodical Press
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Rong-Rong Zhang, Yan Xu, published by Shanxi Medical Periodical Press
This work is licensed under the Creative Commons Attribution 4.0 License.