Nurses’ knowledge, perceptions, and behaviors regarding antineoplastic drugs: the mediating role of protective knowledge†

Characteristics	Number of participants, n (%)	Using warning labels				Using protective masks
Characteristics	Number of participants, n (%)	Yes, n (%)	No, n (%)	χ²/t	P	Single-layer surgical mask, n (%)	Double-layer surgical mask, n (%)	N95, n (%)	3M, n (%)	χ²/F	P
Age (years, Mean (SD))	30.19 (6.24)	32.35 (7.27)	29.87 (6.02)	2.36^a	0.019	30.19 (5.79)	30.63 (6.43)	29.92 (6.62)	28.92 (6.63)	0.37^b	0.775
BMI (kg/m²)				0.01^c	0.996					0.30^d	0.583
<18.5	62 (20.3)	8 (20.0)	54 (20.4)			23 (20.2)	19 (20.1)	15 (16.9)	5 (41.7)
18.5–23.9	206 (67.5)	27 (67.5)	179 (67.5)			82 (71.9)	58 (64.4)	60 (67.4)	6 (50.0)
≥24	37 (12.1)	5 (12.5)	32 (12.1)			9 (7.9)	13 (14.4)	14 (15.7)	1 (8.3)
Length of service (years)				4.73^c	0.094					1.00^d	0.317
<3.81	100 (32.8)	8 (20.0)	92 (34.7)			36 (31.6)	24 (26.7)	34 (38.2)	6 (0.5)
3.81–10.27	101 (33.1)	13 (32.5)	88 (33.2)			38 (33.3)	36 (40.0)	24 (27.0)	3 (0.25)
>10.27	104 (34.1)	19 (47.5)	85 (32.1)			40 (35.1)	30 (33.3)	31 (34.8)	3 (0.25)
Married				3.91^c	0.048					1.15^d	0.284
No	155 (50.8)	14 (35.0)	141 (53.2)			56 (49.1)	42 (46.7)	50 (56.2)	7 (58.3)
Yes	150 (49.2)	26 (65.0)	124 (46.8)			58 (50.9)	48 (53.3)	39 (43.8)	5 (41.7)
Education (Years)				2.37^c	0.124					3.61^d	0.057
<16	80 (26.2)	6 (15.0)	74 (27.9)			22 (19.3)	26 (28.9)	29 (32.6)	3 (25.0)
≥16	225 (73.8)	34 (85.0)	191 (72.1)			92 (80.7)	64 (71.1)	60 (67.4)	9 (75.0)
Department				18.91^c	<0.001					0.60^d	0.439
Gynaecology	61 (33.1)	17 (42.5)	84 (31.7)			32 (28.1)	34 (37.8)	34 (38.2)	1 (8.3)
Oncology	143 (20.0)	16 (40.0)	45 (17.0)			20 (17.5)	21 (23.3)	18 (20.2)	2 (16.7)
Other	101 (46.9)	7 (17.5)	136 (51.3)			62 (54.4)	35 (38.9)	37 (41.6)	9 (75.0

Note: BMI, body mass index;

a Statistics were estimated by t-test;

b Statistics were estimated by ANOVA;

c Statistics were estimated by the χ² test;

d Statistics were estimated by the Mantel-Haenszel χ² test.

Association matrix of protective training for AD exposure, protective knowledge, using warning labels and using protective masks.

Table 2

Association between protective training regarding AD exposure, protective knowledge, and use of warning labels.

Items	Protective knowledge (M, β, 95% CI)	Warning label use (Y, OR, 95% CI)
Items	Model 1 X→M	Model 2 X→Y	Model 3 X+M→Y
Protective training (X)
No	Reference	Reference	Reference
Yes	0.361 (0.173, 0.550)^***	4.270 (1.424, 12.806)^**	3.762 (1.242, 11.396)^*
Protective knowledge (M)			1.751 (1.019, 3.010)^*

Note: All effect sizes were adjusted for age, BMI, length of service, marital status, education, and department;

*** P < 0.001,

** P < 0.01,

* P < 0.05.

Mediation effect of protective knowledge on the association of protective training regarding AD exposure with warning label use.
*Note*: The proportion of mediation = 23.4%.

Table 3

Association between protective training regarding AD exposure, protective knowledge, and using protective masks.

Items	Protective knowledge (M, β, 95% CI)	Protective mask use (Y, OR, 95% CI)
Items	Model 1 X→M	Model 2 X→Y	Model 3 X+M→Y
Protective training (X)
No	Reference	Reference	Reference
Yes	0.361 (0.173, 0.550)^***	2.087 (1.314, 3.317)^**	1.836 (1.145, 2.944)^*
Protective knowledge (M)			1.545 (1.165, 2.047)^*

Note: All effect sizes were adjusted for age, BMI, length of service, marital status, education, and department;

*** P < 0.001,

** P < 0.01,

* P < 0.05.

Mediation effect of protective knowledge on the association of protective training regarding AD exposure with protective mask use.
*Note*: The proportion of mediation =27.2%.

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DOI: https://doi.org/10.2478/fon-2022-0017 | Journal eISSN: 2544-8994 | Journal ISSN: 2097-5368

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Language: English

Page range: 155 - 163

Submitted on: Dec 14, 2021

Accepted on: Feb 24, 2022

Published on: Aug 3, 2022

Published by: Shanxi Medical Periodical Press

In partnership with: Paradigm Publishing Services

Keywords:

antineoplastic drugs,

Chinese nurses,

developed city,

mediation,

occupational exposure

Related subjects:

Medicine,

Assistive professions, nursing

© 2022 Ning Liu, Hong Lu, Xiao-Qing Yi, Yang Yang, Xiao-Hong Huang, published by Shanxi Medical Periodical Press
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 9 (2022): Issue 2 (June 2022)

Nurses’ knowledge, perceptions, and behaviors regarding antineoplastic drugs: the mediating role of protective knowledge†

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Table 2

Figure 2

Table 3

Figure 3

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