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Topical use of ozone effectively alleviates the acute symptoms and quality of life of patients with moderate to severe bullous pemphigoid: a randomized controlled trial† Cover

Topical use of ozone effectively alleviates the acute symptoms and quality of life of patients with moderate to severe bullous pemphigoid: a randomized controlled trial†

Frontiers of Nursing
Volume 8 (2021): Issue 3 (September 2021)
By: ,  ,  ,  ,  ,   and    
Open Access
|Sep 2021
Figures & tables

Figures & Tables

Figure 1

Research object screening flow chart. BPDAI, bullous pemphigoid disease area index.

Figure 2

Different treatment vesicle dry scab, erosion drying time (day) box chart.

Figure 3

Contour plots of itch scores of the two groups at different times.

Figure 4

Sleep score profiles of the two groups at different times.

Figure 5

Comparison of DLQI scores before and after different treatments (score) box chart.

Comparison of basic data between two groups of patients_

IndexCasesGenderAge (years)BPDAI score
MaleFemale
Ozone group37181975.50 ± 7.65162.16 ± 23.37
Control group37162174.70 ± 8.18164.22 ± 22.12
t/χ2 0.218−0.3520.388
P 0.8160.7260.699

The test of different effect of BPDAI observation index_

IndicatorsVariableFP
BPDAI
Time of therapy813.319<0.001
Group16.562<0.001
Time*Group8.2170.001
Vesicle
Time of therapy558.974<0.001
Group0.2530.616
Time*Group0.2240.791
Erythema
Time of therapy259.040<0.001
Group16.944<0.001
Time*Group11.182<0.001
Skin lesion
Time of therapy366.323<0.001
Group0.0020.960
Time*Group0.3390.718
DOI: https://doi.org/10.2478/fon-2020-0024 | Journal eISSN: 2544-8994 | Journal ISSN: 2097-5368
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Language: English
Page range: 233 - 240
Submitted on: Apr 1, 2021
Accepted on: Jun 9, 2021
Published on: Sep 21, 2021
Published by: Shanxi Medical Periodical Press
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
bullous pemphigoid,
erosion,
erythema,
external use,
itch,
moderate-severe,
ozone,
quality of life
Related subjects:
Medicine,
Assistive professions, nursing

© 2021 Li Li, Li-Yun Sang, Wen-Guang Zhang, Tong Wang, Shu-Ping Guo, Hong-Zhou Cui, Hong-Ye Liu, published by Shanxi Medical Periodical Press
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 8 (2021): Issue 3 (September 2021)
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