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Topical use of ozone effectively alleviates the acute symptoms and quality of life of patients with moderate to severe bullous pemphigoid: a randomized controlled trial†

Frontiers of Nursing
Volume 8 (2021): Issue 3 (September 2021)
By:
Open Access
|Sep 2021

Figures & Tables

Figure 1

Research object screening flow chart. BPDAI, bullous pemphigoid disease area index.
Research object screening flow chart. BPDAI, bullous pemphigoid disease area index.

Figure 2

Different treatment vesicle dry scab, erosion drying time (day) box chart.
Different treatment vesicle dry scab, erosion drying time (day) box chart.

Figure 3

Contour plots of itch scores of the two groups at different times.
Contour plots of itch scores of the two groups at different times.

Figure 4

Sleep score profiles of the two groups at different times.
Sleep score profiles of the two groups at different times.

Figure 5

Comparison of DLQI scores before and after different treatments (score) box chart.
Comparison of DLQI scores before and after different treatments (score) box chart.

Comparison of basic data between two groups of patients_

IndexCasesGenderAge (years)BPDAI score
MaleFemale
Ozone group37181975.50 ± 7.65162.16 ± 23.37
Control group37162174.70 ± 8.18164.22 ± 22.12
t/χ2 0.218−0.3520.388
P 0.8160.7260.699

The test of different effect of BPDAI observation index_

IndicatorsVariableFP
BPDAI
Time of therapy813.319<0.001
Group16.562<0.001
Time*Group8.2170.001
Vesicle
Time of therapy558.974<0.001
Group0.2530.616
Time*Group0.2240.791
Erythema
Time of therapy259.040<0.001
Group16.944<0.001
Time*Group11.182<0.001
Skin lesion
Time of therapy366.323<0.001
Group0.0020.960
Time*Group0.3390.718
DOI: https://doi.org/10.2478/fon-2020-0024 | Journal eISSN: 2544-8994 | Journal ISSN: 2097-5368
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Language: English
Page range: 233 - 240
Submitted on: Apr 1, 2021
Accepted on: Jun 9, 2021
Published on: Sep 21, 2021
Published by: Shanxi Medical Periodical Press
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
bullous pemphigoid,
erosion,
erythema,
external use,
itch,
moderate-severe,
ozone,
quality of life
Related subjects:
Medicine,
Assistive professions, nursing

© 2021 Li Li, Li-Yun Sang, Wen-Guang Zhang, Tong Wang, Shu-Ping Guo, Hong-Zhou Cui, Hong-Ye Liu, published by Shanxi Medical Periodical Press
This work is licensed under the Creative Commons Attribution 4.0 License.

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