The prevalence of ER-low-positive breast cancer and its relation to tumor characteristics in Syria

Figures & Tables

ER-staining intensity subtypes

Parameter		Low N=28 (23.33%)		High N=30 (25%)		P value

		n	%	n	%
Age, years	≤46	14	50	4	13.33	0.003
Age, years	>46	14	50	26	86.67	0.003
Tumor size, cm	≤2cm	10	35.71	6	23.33	0.189
	2.1 to 5	12	42.86	20	61.67
	>5	6	21.43	4	15
Diagnosis	IDC	26	92.86	26	86.67	0.695
	ILC	2	7.14	2	6.67
	Mucinous	0	0	2	6.67
Histological grade	I	0	0	0	0	0.05
	II	16	57.14	28	93.33
	III	6	42.86	2	6.67
Stage	I	0	0	2	6.67	0.009
	II	6	21.43	16	53.33
	III	22	78.57	12	40
Nodal stage, pN	1 to 4	2	7.14	14	46.67	0.001
Nodal stage, pN	>4	26	92.86	16	53.33	0.001
LNR	Low risk (0–0.2)	2	7.14	16	53.33	0.001
	Intermediate risk (>0.2–0.65)	22	78.57	12	40
	High risk (>0.65–1)	4	14.29	2	6.67

ER-staining intensity subtypes N=120

Parameter		Negative N=38 (31.67%)		Low N=28 (23.33%)		Moderate N=24 (20%)		High N=30 (25%)		P value

		n	%	n	%	n	%	n	%
Age, years	≤46	22	57.89	14	50	16	66.67	4	13.33	0.018
Age, years	>46	16	42.11	14	50	8	33.33	26	86.67	0.018
Tumor Size, cm	≤2cm	2	5.26	10	35.71	10	41.67	6	23.33	0.18
	2.1 to 5	30	78.95	12	42.86	12	50	20	61.67
	>5	6	15.79	6	21.43	2	8.33	4	15
Diagnosis	IDC	34	89.47	26	92.86	22	91.67	26	86.67	0.812
	ILC	4	10.53	2	7.14	0	0	2	6.67
	Mucinous	0	0	0	0	2	8.33	2	6.67
Histological grade	I	0	0	0	0	2	8.33	0	0	0.01
	II	34	89.47	16	57.14	22	91.67	28	93.33
	III	4	10.53	6	42.86	0	0	2	6.67
Stage	I	2	5.26	0	0	2	8.33	2	6.67	0.131
	II	24	63.16	6	21.43	10	41.67	16	53.33
	III	12	31.58	22	78.57	12	50	12	40
Nodal stage, pN	1 to 4	20	52.63	2	7.14	10	41.67	14	46.67	0.035
Nodal stage, pN	>4	18	47.37	26	92.86	14	58.33	16	53.33	0.035
LNR	Low risk (0–0.2)	20	52.63	2	7.14	10	41.67	16	53.33	0.046
	Intermediate risk (>0.2–0.65)	18	47.37	22	78.57	18	50	12	40
	High risk (>0.65–1)	0	0	4	14.29	2	8.33	2	6.67