References
- Abbasi Z, Tabatabaei SRF, Mazaheri Y, Barati F, Morovvati, H. Effects of sesame oil on the reproductive parameters of diabetes mellitus-induced male rats. World J Mens Health 3, 141–149, 2013.10.5534/wjmh.2013.31.2.141
- Agarwal A, Saleh RA. Role of oxidants in male infertility: rationale, significance, and treatment. Urol Clin North Am 29, 817–828, 2002.10.1016/S0094-0143(02)00081-2
- Agarwal A, Said TM. Oxidative stress, DNA damage and apoptosis in male infertility: a clinical approach. BJU Int 95, 503–507, 2005.10.1111/j.1464-410X.2005.05328.x15705068
- Aktas C, Kanter M, Erboga M, Timurkan H. Effects of experimental diabetes on testis proliferations and apoptosis in rats. J Exp Clin Med 28, 94–98, 2011.10.5835/jecm.omu.28.03.001
- Almeida SA, Kempinas WG, Lamano Carvalho TL. Sexual behavior and fertility of male rats submitted to prolonged immobilization-induced stress. Braz J Med Biol Res 33, 1105–1109, 2000.10.1590/S0100-879X200000090001910973146
- Amaral S, Moreno AJ, Santos MS, Seica R, Ramalho-Santos J. Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes. Theriogenology 66, 2056–2067, 2006.10.1016/j.theriogenology.2006.06.00616860381
- Badalzadeh R, Layeghzadeh N, Alihemmati A, Mohammadi M. Beneficial effect of troxerutin on diabetes-induced vascular damages in rat aorta: histopathological alterations and antioxidation mechanism. Int J Endocrinol Metab 13, e25969, 2015.10.5812/ijem.25969438623125926856
- Badalzadeh R, Chodari L, Ghorbanzadeh V. Troxerutin, a bioflavonoid, improves oxidative stress in blood of streptozotocin-induced type-1 diabetic rats. IJPS 13, 75–86, 2017.
- Cai L, Chen S, Evans T, Deng DX, Mukherjee K, Chakrabarti S. Apoptotic germ-cell death and testicular damage in experimental diabetes: prevention by endothelin antagonism. Urol Res 28, 342–347, 2000.10.1007/s00240000013411127715
- Chandrashekar KN. Evidence of oxidative stress and mitochondrial dysfunctions in the testis of prepubertal diabetic rats. Int J Impot Res 21, 198–206, 2009.10.1038/ijir.2009.919444988
- Elangovan P, Jalaludeen AM, Ramakrishnan R, Pari L. Protective effect of troxerutin on nickel-induced testicular toxicity in Wistar rats. J Environ Pathol Toxicol Oncol 35, 133–146, 2016.10.1615/JEnvironPatholToxicolOncol.201601538427481491
- Fan SH, Zhang ZF, Zheng YL, Lu J, Wu DM, Shan Q, Hu B, Wang YY. Troxerutin protects the mouse kidney from d-galactose-caused injury through anti-inflammation and anti-oxidation. Int Immunopharmacol 9, 91–96, 2009.10.1016/j.intimp.2008.10.00819000936
- Farajdokht F, Amani M, Bavil FM, Alihemmati A, Mohaddes G, Babri S. Troxerutin protects hippocampal neurons against amyloid beta-induced oxidative stress and apoptosis. EXCLI J 16, 1081–1089, 2017.
- Feng SL, Li SH, Wang Y, Chen CC, Gao B. Effect of ligustrum fruit extract on reproduction in experimental diabetic rats. Asian J Androl 23, 71–73, 2001.
- Gao F, Gao E, Yue TL, Ohlstein EH, Lopez BL, Christopher TA, Ma XL. Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation 105, 1497–1502, 2002.10.1161/01.CIR.0000012529.00367.0F11914261
- Geetha R, Yogalakshmi B, Sreeja S, Bhavani K, Anuradha CV. Troxerutin suppresses lipid abnormalities in the heart of high-fat–high-fructose diet-fed mice. Mol Cell Biochem 387, 123–134, 2014.10.1007/s11010-013-1877-224173620
- Guneli E, Tugyan K, Ozturk H, Gumustekin M, Cilaker S, Uysal N. Effect of melatonin on testicular damage in streptozotocin-induced diabetes rats. Eur Surg Res 40, 354–360, 2008.10.1159/00011803218303272
- Hsia Y, Neubert AC, Rani F, Viner RM, Hindmarsh PC, Wong IC. An increase in the prevalence of type 1 and 2 diabetes in children and adolescents: results from prescription data from a UK general practice database. Br J Clin Pharmacol 67, 242–249, 2009.10.1111/j.1365-2125.2008.03347.x267038219260863
- Jalali M, Hassanipour M, Hajizadeh M, Khanamani Falahati Pour S, Khoshdel A, Roustai F, Rezai M, Mahmoodi M. Troxerutin chronic treatment protects against fructose-induced metabolic syndrome in male rats. IJML 4, 201–210, 2017.
- Jangir RN, Jain GC. Diabetes mellitus induced impairment of male reproductive functions: a review. Curr Diabetes Rev 10, 147–157, 2014.10.2174/157339981066614060611174524919656
- Kanter M, Aktas C, Erboga M. Protective effects of quercetin against apoptosis and oxidative stress in streptozotocin-induced diabetic rat testis. Food Chem Toxicol 50, 719–725, 2012.10.1016/j.fct.2011.11.05122166789
- Keyhanmanesh R, Hamidian G, Alipour MR, Ranjbar M, Oghbaei H. Protective effects of sodium nitrate against testicular apoptosis and spermatogenesis impairments in streptozotocin-induced diabetic male rats. Life Sci 211, 63–73, 2018.10.1016/j.lfs.2018.09.01930205097
- Keyhanmanesh R, Hamidian G, Alipour MR, Oghbaei H. Beneficial treatment effects of dietary nitrate supplementation on testicular injury in Streptozotocin-induced diabetic male rats. Reprod Biomed Online 39, 357–371, 2019.10.1016/j.rbmo.2018.11.02730952494
- Kheirollahi A, Abbaszadeh A, Anbari K, Rostami B, Ahangari A, Hasanvand A, Gholami M. Troxerutin protect sperm, seminiferous epithelium and pituitary-gonadal axis from torsion-detorsion injury: An experimental study. Int J Reprod Biomed 16, 315–322, 2018.10.29252/ijrm.16.5.315
- Kianifard D, Sadrkhanlou RA, Hasanzadeh S. The ultrastructural changes of the Sertoli and Leydig cells following streptozotocin induced diabetes. Iran J Basic Med Sci 15, 623–635, 2012.
- King AJ. The use of animal models in diabetes research. Br J Pharmacol 166, 877–894, 2012.10.1111/j.1476-5381.2012.01911.x341741522352879
- Kushwaha S, Jena GB. Enalapril reduces germ cell toxicity in streptozotocin-induced diabetic rat: investigation on possible mechanisms. Naunyn Schmiedebergs Arch Pharmacol 385, 111–124, 2012.10.1007/s00210-011-0707-x22071577
- La Vignera S, Condorelli RA, Di Mauro M, Lo Presti D, Mongioi LM, Russo G, Calogero AE. Reproductive function in male patients with type 1 diabetes mellitus. Andrology 3, 1082–1087, 2015.10.1111/andr.1209726446574
- Lu YX, Zhang Q, Li J, Sun YX, Wang LY, Cheng WM, Hu XY. Antidiabetic effects of total flavonoids from Litsea Coreana leve on fat-fed, streptozotocin-induced type 2 diabetic rats. Am J Chin Med 38, 713–725, 2010.10.1142/S0192415X1000818420626057
- Mokhtari B, Badalzadeh R, Alihemmati A, Mohammadi M. Phosphorylation of GSK-3β and reduction of apoptosis as targets of troxerutin effect on reperfusion injury of diabetic myocardium. Eur J Pharmacol 765, 316–321, 2015.10.1016/j.ejphar.2015.08.05626341011
- Muller D, Jones PM, Persaud SJ. Autocrine anti-apoptotic and proliferative effects of insulin in pancreatic β-cells. FEBS Lett 580, 6977–6980, 2006.10.1016/j.febslet.2006.11.06617161395
- Naderi R, Mohaddes G, Mohammadi M, Ghaznavi R, Ghyasi R, Vatankhah AM. Voluntary exercise protects heart from oxidative stress in diabetic rats. Adv Pharm Bull 5, 231–236, 2015.10.15171/apb.2015.032451709326236662
- Oghbaei H, Asl NA, Sheikhzadeh F. Can regular moderate exercise lead to changes in miRNA-146a and its adapter proteins in the kidney of streptozotocin-induced diabetic male rats? Endocr Regul 51, 145–152, 2017.10.1515/enr-2017-001528858844
- Oghbaei H, Alipour MR, Hamidian G, Ahmadi M, Ghorbanzadeh V, Keyhanmanesh R. Two months sodium nitrate supplementation alleviates testicular injury in streptozotocin-induced diabetic male rats. Exp Physiol 103, 1603–1617, 2018.10.1113/EP08719830088840
- Oghbaei H, Alipour MR, Mohaddes G, Hamidian GR, Keyhanmanesh R. Evaluation of ameliorative effect of sodium nitrate in experimental model of streptozotocin-induced diabetic neuropathy in male rats. Endocr Regul 53, 14–25, 2019.10.2478/enr-2019-000331517620
- Panat NA, Maurya DK, Ghaskadbi SS, Sandur SK. Troxerutin, a plant flavonoid, protects cells against oxidative stress-induced cell death through radical scavenging mechanism. Food Chem 194, 32–45, 2016.10.1016/j.foodchem.2015.07.07826471524
- Pari L, Monisha P, Mohamed Jalaludeen A. Beneficial role of diosgenin on oxidative stress in aorta of streptozotocin induced diabetic rats. Eur J Pharmacol 691, 143–150, 2012.10.1016/j.ejphar.2012.06.03822771295
- Pourmemar E, Majdi A, Haramshahi M, Talebi M, Karimi P, Sadigh-Eteghad S. Intranasal cerebrolysin attenuates learning and memory impairments in D-galactose-induced senescence in mice. Exp Gerontol 87, 16–22, 2017.10.1016/j.exger.2016.11.01127894939
- Sampath S, Karundevi B. Effect of troxerutin on insulin signaling molecules in the gastrocnemius muscle of high fat and sucrose-induced type-2 diabetic adult male rat. Mol Cell Biochem 395, 11–27, 2014.10.1007/s11010-014-2107-224880482
- Shrilatha B, Muralidhara. Occurrence of oxidative impairments, response of antioxidant defences and associated biochemical perturbations in male reproductive milieu in the Streptozotocin-diabetic rat. Int J Androl 30, 508–518, 2007.10.1111/j.1365-2605.2007.00748.x17573857
- Soudamani S, Malini T, Balasubramanian K. Effects of streptozotocin-diabetes and insulin replacement on the epididymis of prepubertal rats: histological and histomorphometric studies. Endocr Res 31, 81–98, 2005.10.1080/0743580050022919316353669
- Wu XH, Yang SH, Duan DY, Cheng HH, Bao YT, Zhang Y. Anti-apoptotic effect of insulin in the control of cell death and neurologic deficit after acute spinal cord injury in rats. J Neurotrauma 24, 1502–1512, 2007.10.1089/neu.2006.022817892411
- Yaghoubi A, Shahedi A, Akbari H, Nematollahi-Mahani SN. Do insulin replacement and omega3 protect the male reproductive function of the streptozotocin-induced diabetic mice? J Nutr Metab 2017, 6102985, 2017.10.1155/2017/6102985552318728770110
- Yu Y, Zheng G. Troxerutin protects against diabetic cardiomyopathy through NF-κB/AKT/IRS1 in a rat model of type 2 diabetes. Mol Med Rep 15, 3473–3478, 2017.10.3892/mmr.2017.6456543628428440404
- Zhang ZF, Shan Q, Zhuang J, Zhang YQ, Wang X, Fan SH, Lu J, Wu DM, Hu B, Zheng YL. Troxerutin inhibits 2, 2’, 4, 4’-tetrabromodiphenyl ether (BDE-47)-induced hepatocyte apoptosis by restoring proteasome function. Toxicol Lett 233, 246–257, 2015.10.1016/j.toxlet.2015.01.01725639565
- Zhang S, Yuan L, Zhang L, Li C, Li J. Prophylactic use of Troxerutin can delay the development of diabetic cognitive dysfunction and improve the expression of Nrf2 in the hippocampus on STZ diabetic rats. Behav Neurol 2018, 8678539, 2018.10.1155/2018/8678539592513729849815
- Zhao Y, Tan Y, Dai J, Li B, Guo L, Cui J, Wang G, Shi X, Zhang X, Mellen N, Li W. Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice. Toxicol Lett 200, 100–106, 2011.10.1016/j.toxlet.2010.11.00121078376