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STAT3 and Nrf2 pathways modulate the protective effect of verapamil on lung injury of diabetic rats Cover

STAT3 and Nrf2 pathways modulate the protective effect of verapamil on lung injury of diabetic rats

Open Access
|Nov 2018

References

  1. Asmat U, Abad K, Ismail K. Diabetes mellitus and oxidative stress-A concise review. Saudi Pharm J 24, 547-553, 2016.10.1016/j.jsps.2015.03.013
  2. Balakumaran A, Campbell GA, Moslen MT. Calcium channel blockers induce thymic apoptosis in vivo in rats. Toxicol Appl Pharmacol 139, 122-127, 1996.10.1006/taap.1996.0150
  3. Brown DM, Donaldson K, Borm PJ, Schins RP, Dehnhardt M, Gilmour P, Stone V. Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles. Am J Physiol Lung Cell Mol Physiol 286, L344-L353, 2004.10.1152/ajplung.00139.2003
  4. Buege JA, Aust SD. Microsomal lipid peroxidation. Methods in enzymology 52, 302-310, 1978.10.1016/S0076-6879(78)52032-6
  5. Chawla A, Chawla R, Jaggi S. Microvasular and macrovascular complications in diabetes mellitus: Distinct or continuum? Indian J Endocrinol Metab 20, 546-551, 2016.10.4103/2230-8210.183480491184727366724
  6. Das R, Burke T, Van Wagoner DR, Plow EF. L-type calcium channel blockers exert an antiinflammatory effect by suppressing expression of plasminogen receptors on macrophages. Circ Res 105, 167-175, 2009.10.1161/CIRCRESAHA.109.200311274596919520970
  7. de Rekeneire N, Peila R, Ding J, Colbert LH, Visser M, Shorr RI, Harris TB. Diabetes, hyperglycemia, and inflammation in older individuals: the health, aging and body composition study. Diabetes Care 29, 1902-1908, 2006.10.2337/dc05-232716873800
  8. Godfraind T. Discovery and Development of Calcium Channel Blockers. Front Pharmacol 8, 286, 2017.10.3389/fphar.2017.00286544709528611661
  9. Hashioka S, Klegeris A, McGeer PL. Inhibition of human astrocyte and microglia neurotoxicity by calcium channel blockers. Neuropharmacology 63, 685-691, 2012.10.1016/j.neuropharm.2012.05.0332265908922659089
  10. Heiss EH, Schachner D, Zimmermann K, Dirsch VM. Glucose availability is a decisive factor for Nrf2-mediated gene expression. Redox Biol 21, 359-365, 2013.10.1016/j.redox.2013.06.001375770524024172
  11. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 95, 2409-2415, 1995.10.1172/JCI117936
  12. Hu JF, Zhang GJ, Wang L, Kang PF, Li J, Wang HJ, Gao Q, Chen YQ. Ethanol at low concentration attenuates diabetes induced lung injury in rats model. J Diabetes Res 107-152, 2014.10.1155/2014/107152
  13. Kalantarinia K, Awad AS, Siragy HM. Urinary and renal interstitial concentrations of TNF-alpha increase prior to the rise in albuminuria in diabetic rats.. Kidney Int 64, 1208-1213, 2003.10.1046/j.1523-1755.2003.00237.x
  14. Kedziora-Kornatowska K, Szram S, Kornatowski T, Szadujkis-Szadurski L, Kedziora J, Bartosz G. The effect of verapamil on the antioxidant defence system in diabetic kidney. Clin Chim Acta 322, 105-112, 2002.10.1016/S0009-8981(02)00167-5
  15. Khodneva Y, Shalev A, Frank SJ, Carson AP, Safford MM. Calcium channel blocker use is associated with lower fasting serum glucose among adults with diabetes from the REGARDS study. Diabetes Res Clin Pract 115, 115-121, 2016.2681889410.1016/j.diabres.2016.01.021
  16. Marklund S, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47, 469-474, 1974.10.1111/j.1432-1033.1974.tb03714.x
  17. Mashili F, Chibalin AV, Krook A, Zierath JR. Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin resistance in type 2 diabetes. Diabetes 62, 457-465, 2013.10.2337/db12-0337
  18. Mikawa K, Nishina K, Takao Y, Obara H. ONO-1714, a nitric oxide synthase inhibitor, attenuates endotoxin-induced acute lung injury in rabbits. Anesth Analg 97, 1751-1755, 2003.10.1213/01.ANE.0000086896.90343.13
  19. Miscia S, Marchisio M, Grilli A, Di Valerio V, Centurione L, Sabatino G, Garaci F, Zauli G, Bonvini E, Di Baldassarre A. Tumor necrosis factor alpha (TNF-alpha) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells. Cell Growth Differ 13, 13-18, 2002.
  20. Moron MS, Depierre JW, Mannervik B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochim Biophys Acta 582, 67-78, 1979.10.1016/0304-4165(79)90289-7
  21. Palanisamy GS, Kirk NM, Ackart DF, Shanley CA, Orme IM, Basaraba RJ. Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis. PLoS One 6, e26254, 2011.10.1371/journal.pone.0026254319654222028843
  22. Pitocco D, Fuso L, Conte EG, Zaccardi F, Condoluci C, Scavone G, Incalzi RA, Ghirlanda G. The diabetic lung--a new target organ. Rev Diabet Stud 9, 23-35, 2012.10.1900/RDS.2012.9.23344817122972442
  23. Poudel RR, Kafle NK. Verapamil in Diabetes. Indian J Endocrinol Metab 21, 788-789, 2017.10.4103/ijem.IJEM_190_17562855728989895
  24. Qu P, Roberts J, Li Y, Albrecht M, Cummings OW, Eble JN, Du H, Yan C. Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease. Lung Cancer 63, 341-347, 2009.10.1016/j.lungcan.2008.05.025266499918614255
  25. Said E, Zaitone SA, Eldosoky M, Elsherbiny NM. Nifuroxazide, a STAT3 inhibitor, mitigates inflammatory burden and protects against diabetes-induced nephropathy in rats. Chem Biol Interact 281, 111-120, 2018.10.1016/j.cbi.2017.12.03029291386
  26. Striessnig J, Ortner NJ, Pinggera A. Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets? Curr Mol Pharmacol 8, 110-122, 2015.10.2174/1874467208666150507105845538437125966690
  27. Tabur S, Oguz E, Sabuncu T, Korkmaz H, Celik H. The effects of calcium channel blockers on nephropathy and pigment epithelium-derived factor in the treatment of hypertensive patients with type 2 diabetes mellitus. Clin Exp Hypertens 37, 177-183, 2015.10.3109/10641963.2014.93396425050869
  28. Taghizadeh M, Rashidi AA, Taherian AA, Vakili Z, Mehran M. The protective effect of hydroalcoholic extract of Rosa canina (Dog Rose) fruit on liver function and structure in streptozotocin-induced diabetes in rats. J Diet Suppl 15, 624-635, 2018.2909565210.1080/19390211.2017.136920529095652
  29. Tan Y, Ichikawa T, Li J, Si Q, Yang H, Chen X, Cui T. Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo. Diabetes 60, 625-633, 2011.2127027210.2337/db10-1164302836421270272
  30. Tanaka Y, Kashiwagi A, Ogawa T, Abe N, Asahina T, Ikebuchi M, Shigeta Y. Effect of verapamil on cardiac protein kinase C activity in diabetic rats. Eur J Pharmacol 200, 353-356, 1991.
  31. VanGuilder H, Vrana K, FreemanW. Twenty-five years of quantitative PCR for gene expression analysis. Biotechniques 44, 619-626, 2008.10.2144/0001127761847403618474036
  32. World Health Organization, Global Report on Diabetes. Geneva, 2016. Accessed 30 August 2016.
  33. Xu G, Chen J, Jing G, Shalev A. Preventing beta-cell loss and diabetes with calcium channel blockers. Diabetes 61, 848-856, 2012.10.2337/db11-0955331435422442301
  34. Zhang F, Yang F, Zhao H, An Y. Curcumin alleviates lung injury in diabetic rats by inhibiting NF-kappaB pathway. Clin Exp Pharmacol Physiol 42, 956-963, 2015.10.1111/1440-1681.1243826111829
  35. Zhao J, Yu H, Liu Y, Gibson SA, Yan Z, Xu X, Qin H. Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol 311, L868-L880, 2016.10.1152/ajplung.00281.2016513053627638904
  36. Zheng H, Wu J, Jin Z, Yan LJ. Potential biochemical mechanisms of lung injury in diabetes. Aging Dis 8, 7-16, 2017.2820347810.14336/AD.2016.0627528738828203478
DOI: https://doi.org/10.2478/enr-2018-0024 | Journal eISSN: 1336-0329 | Journal ISSN: 1210-0668
Language: English
Page range: 192 - 198
Published on: Nov 22, 2018
Published by: Slovak Academy of Sciences, Mathematical Institute
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2018 Mervat Z. Mohamed, Heba M. Hafez, Hanaa H. Mohamed, Nagwa M. Zenhom, published by Slovak Academy of Sciences, Mathematical Institute
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.